Gene/Proteome Database (LMPD)

LMPD ID
LMP010632
Gene ID
829306
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
Monogalactosyldiacylglycerol synthase 1
Gene Symbol
MGD1
Synonyms
F11C18.2; MGD1; MGDA; monogalactosyl diacylglycerol synthase 1; MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE; MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE A
Alternate Names
Monogalactosyldiacylglycerol synthase 1
Chromosome
4
EC Number
2.4.1.46
Summary
Encodes an A-type monogalactosyldiacylglycerol (MGDG) synthase. It represents the isoform responsible for the bulk of MGDG synthesis in Arabidopsis.
Orthologs
View orthologs and multiple alignments for MGD1

Proteins

Monogalactosyldiacylglycerol synthase 1
Refseq ID NP_194906
Protein GI 15236072
UniProt ID O81770
mRNA ID NM_119327
Length 533
RefSeq Status REVIEWED
MQNPSTVTQESAAPVFDFFPRLRGLTSRNRSPCSNSDGYALSSSNALYFNGFRTLPSRRMGKTLASLSFNTKSSAGSSLRRFISDFNSFIRFHCDKVVPESFASVGGVGLSSDENGIRENGTGGVLGEEGLPLNGVEADRPKKVLILMSDTGGGHRASAEAIRAAFNQEFGDEYQVFITDLWTDHTPWPFNQLPRSYNFLVKHGTLWKMTYYGTSPRIVHQSNFAATSTFIAREIAQGLMKYQPDIIISVHPLMQHVPLRVLRSKGLLKKIVFTTVITDLSTCHPTWFHKLVTRCYCPSTEVAKRAQKAGLETSQIKVYGLPVRPSFVKPVRPKVELRRELGMDENLPAVLLMGGGEGMGPIEATARALADALYDKNLGEAVGQVLIICGRNKKLQSKLSSLDWKIPVQVKGFITKMEECMGACDCIITKAGPGTIAEAMIRGLPIILNGYIAGQEAGNVPYVVENGCGKFSKSPKEISKIVADWFGPASKELEIMSQNALRLAKPEAVFKIVHDMHELVRKKNSLPQLSCTA
Monogalactosyldiacylglycerol synthase 1
Refseq ID NP_849482
Protein GI 30689152
UniProt ID O81770
mRNA ID NM_179151
Length 504
RefSeq Status REVIEWED
MQNPSTVTQESAAPVFDFFPRLRGLTSRNRSPCSNSDGYALSSSNALYFNGFRTLPSRRMGKTLASLSFNTKSSAGSSLRRFISDFNSFIRFHCDKVVPESFASVGGVGLSSDENGIRENGTGGVLGEEGLPLNGVEADRPKKVLILMSDTGGGHRASAEAIRAAFNQEFGDEYQVFITDLWTDHTPWPFNQLPRSYNFLVKHGTLWKMTYYGTSPRIVHQSNFAATSTFIAREIAQGLMKYQPDIIISVHPLMQHVPLRVLRSKGLLKKIVFTTVITDLSTCHPTWFHKLVTRCYCPSTEVAKRAQKAGLETSQIKVYGLPVRPSFVKPVRPKVELRRELGMDENLPAVLLMGGGEGMGPIEATARALADALYDKNLGEAVGQVLIICGRNKKLQSKLSSLDWKIPVQVKGFITKMEECMGACDCIITKAGPGTIAEAMIRGLPIILNGYIAGQVSRECTVRGGKRMWEILKITERDIEDCSGLVWTGIERVGDNVTECIEAG

Gene Information

Entrez Gene ID
829306
Gene Name
Monogalactosyldiacylglycerol synthase 1
Gene Symbol
MGD1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009941 IDA:TAIR C chloroplast envelope
GO:0009706 IDA:TAIR C chloroplast inner membrane
GO:0009536 IDA:TAIR C plastid
GO:0046509 IMP:TAIR F 1,2-diacylglycerol 3-beta-galactosyltransferase activity
GO:0035250 TAS:TAIR F UDP-galactosyltransferase activity
GO:0008194 IDA:TAIR F UDP-glycosyltransferase activity
GO:0030246 IEA:InterPro F carbohydrate binding
GO:0009793 IMP:TAIR P embryo development ending in seed dormancy
GO:0009247 IDA:TAIR P glycolipid biosynthetic process
GO:0030259 IEA:InterPro P lipid glycosylation
GO:0010027 IMP:TAIR P thylakoid membrane organization

KEGG Pathway Links

KEGG Pathway ID Description
ath00561 Glycerolipid metabolism
ath01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-401 glycolipid biosynthesis
PWY-5410 traumatin and (Z)-3-hexen-1-yl acetate biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR009695 Diacylglycerol glucosyltransferase, N-terminal
IPR007235 Glycosyl transferase, family 28, C-terminal

UniProt Annotations

Entry Information

Gene Name
Monogalactosyldiacylglycerol synthase 1
Protein Entry
MGDG1_ARATH
UniProt ID
O81770
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=O81770-1; Sequence=Displayed; Name=2; IsoId=O81770-2; Sequence=VSP_035387, VSP_035388; Note=Derived from EST data. No experimental confirmation available.;
Biophysicochemical Properties pH dependence: Optimum pH is 7.5.;
Catalytic Activity UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol = UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol.
Developmental Stage Highly expressed throughout whole developmental stages. Transient increase in embryos at the globular stage. {ECO:0000269|PubMed:11553816, ECO:0000269|PubMed:17940034}.
Disruption Phenotype Plants show defects in chloroplast biogenesis and a dwarf and albino phenotype. The amount of monogalactosyldiacylglycerol was reduced by 98% in the mutant leaves, indicating that MGD2/MGD3 cannot compensate for loss of MGD1 function. {ECO:0000269|PubMed:10869420}.
Function Involved in the synthesis of the major structural component of photosynthetic membranes. Required for proper thylakoid membrane biogenesis. Does not discriminate between prokaryotic (18:1/16:0) or eukaryotic (18:2/18:2) 1,2- diacylglycerol species, but operates with some preference for the prokaryotic one. {ECO:0000269|PubMed:10869420, ECO:0000269|PubMed:11171188, ECO:0000269|PubMed:11553816, ECO:0000269|PubMed:17940034}.
Induction Induced by illumination and cytokinin treatment in etiolated seedlings. Not induced by phosphate deprivation. {ECO:0000269|PubMed:11553816, ECO:0000269|PubMed:14730084}.
Similarity Belongs to the glycosyltransferase 28 family. {ECO:0000305}.
Subcellular Location Plastid, chloroplast inner membrane {ECO:0000305|PubMed:11171188, ECO:0000305|PubMed:11553816}.
Subunit Homodimer. {ECO:0000250}.
Tissue Specificity Expressed in roots, stems, leaves, flowers, siliques and seeds. {ECO:0000269|PubMed:11171188, ECO:0000269|PubMed:11553816, ECO:0000269|PubMed:14730084}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010632 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15236072 RefSeq NP_194906 533 Monogalactosyldiacylglycerol synthase 1
30689152 RefSeq NP_849482 504 Monogalactosyldiacylglycerol synthase 1

Identical Sequences to LMP010632 proteins

Reference Database Accession Length Protein Name
GI:15236072 GenBank ABA30499.1 533 Sequence 10 from patent US 6924092
GI:15236072 GenBank ACW85293.1 533 Sequence 1200 from patent US 7569389
GI:15236072 GenBank ACW87403.1 533 Sequence 4084 from patent US 7569389
GI:15236072 GenBank AEE85956.1 533 Monogalactosyldiacylglycerol synthase 1 [Arabidopsis thaliana]
GI:30689152 GenBank AEE85957.1 504 Monogalactosyldiacylglycerol synthase 1 [Arabidopsis thaliana]
GI:15236072 GenBank AHL38670.1 533 glycosyltransferase, partial [Arabidopsis thaliana]
GI:15236072 SwissProt O81770.1 533 RecName: Full=Monogalactosyldiacylglycerol synthase 1, chloroplastic; Short=AtMGD1; AltName: Full=MGDG synthase type A; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010632 proteins

Reference Database Accession Length Protein Name
GI:30689152 EMBL CAA19745.1 533 monogalactosyldiacylglycerol synthase - like protein [Arabidopsis thaliana]
GI:30689152 EMBL CAB79896.1 533 monogalactosyldiacylglycerol synthase-like protein [Arabidopsis thaliana]
GI:15236072 GenBank ACW85292.1 567 Sequence 1199 from patent US 7569389
GI:15236072 GenBank EFH45572.1 533 hypothetical protein ARALYDRAFT_913288 [Arabidopsis lyrata subsp. lyrata]
GI:30689152 GenBank AEE85956.1 533 Monogalactosyldiacylglycerol synthase 1 [Arabidopsis thaliana]
GI:15236072 GenBank EOA17918.1 533 hypothetical protein CARUB_v10006327mg [Capsella rubella]
GI:15236072 RefSeq XP_002869313.1 533 hypothetical protein ARALYDRAFT_913288 [Arabidopsis lyrata subsp. lyrata]
GI:15236072 RefSeq XP_006285020.1 533 hypothetical protein CARUB_v10006327mg [Capsella rubella]
GI:30689152 RefSeq XP_010432819.1 505 PREDICTED: monogalactosyldiacylglycerol synthase 1, chloroplastic-like isoform X2 [Camelina sativa]
GI:30689152 RefSeq XP_010437995.1 505 PREDICTED: monogalactosyldiacylglycerol synthase 1, chloroplastic-like isoform X2 [Camelina sativa]
GI:15236072 RefSeq XP_010447539.1 533 PREDICTED: monogalactosyldiacylglycerol synthase 1, chloroplastic isoform X1 [Camelina sativa]
GI:30689152 RefSeq XP_010447540.1 504 PREDICTED: monogalactosyldiacylglycerol synthase 1, chloroplastic isoform X2 [Camelina sativa]