Gene/Proteome Database (LMPD)
LMPD ID
LMP010705
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
fatA acyl-ACP thioesterase
Gene Symbol
Synonyms
AtFaTA; FaTA; fatA acyl-ACP thioesterase
Alternate Names
fatA acyl-ACP thioesterase
Chromosome
3
EC Number
3.1.2.14
Summary
Encodes a FatA acyl-ACP thioesterase
Orthologs
Proteins
| fatA acyl-ACP thioesterase | |
|---|---|
| Refseq ID | NP_189147 |
| Protein GI | 15230256 |
| UniProt ID | Q42561 |
| mRNA ID | NM_113415 |
| Length | 362 |
| RefSeq Status | REVIEWED |
| MLKLSCNVTDSKLQRSLLFFSHSYRSDPVNFIRRRIVSCSQTKKTGLVPLRAVVSADQGSVVQGLATLADQLRLGSLTEDGLSYKEKFVVRSYEVGSNKTATVETIANLLQEVGCNHAQSVGFSTDGFATTTTMRKLHLIWVTARMHIEIYKYPAWGDVVEIETWCQSEGRIGTRRDWILKDSVTGEVTGRATSKWVMMNQDTRRLQKVSDDVRDEYLVFCPQEPRLAFPEENNRSLKKIPKLEDPAQYSMIGLKPRRADLDMNQHVNNVTYIGWVLESIPQEIVDTHELQVITLDYRRECQQDDVVDSLTTTTSEIGGTNGSATSGTQGHNDSQFLHLLRLSGDGQEINRGTTLWRKKPSS | |
Gene Information
Entrez Gene ID
Gene Name
fatA acyl-ACP thioesterase
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0009507 | IEA:UniProtKB-KW | C | chloroplast |
| GO:0016297 | IDA:TAIR | F | acyl-[acyl-carrier-protein] hydrolase activity |
| GO:0016295 | IEA:UniProtKB-EC | F | myristoyl-[acyl-carrier-protein] hydrolase activity |
| GO:0004320 | IEA:UniProtKB-EC | F | oleoyl-[acyl-carrier-protein] hydrolase activity |
| GO:0016296 | IEA:UniProtKB-EC | F | palmitoyl-[acyl-carrier-protein] hydrolase activity |
| GO:0006633 | IGI:UniProtKB | P | fatty acid biosynthetic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ath00061 | Fatty acid biosynthesis |
Domain Information
UniProt Annotations
Entry Information
Gene Name
fatA acyl-ACP thioesterase
Protein Entry
FATA1_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Biophysicochemical Properties | Kinetic parameters: KM=13.9 uM for myristoyl-ACP (14:0-ACP) {ECO:0000269|PubMed:12061798}; KM=8.9 uM for myristoleoyl-ACP (14:1-ACP) {ECO:0000269|PubMed:12061798}; KM=4.9 uM for palmitoyl-ACP (16:0-ACP) {ECO:0000269|PubMed:12061798}; KM=4.9 uM for palmitoleoyl-ACP (16:1-ACP) {ECO:0000269|PubMed:12061798}; KM=5.0 uM for stearoyl-ACP (18:0-ACP) {ECO:0000269|PubMed:12061798}; KM=3.1 uM for oleoyl-ACP (18:1-ACP) {ECO:0000269|PubMed:12061798}; Note=The catalytic efficiency for 18:1 is at least 20-fold higher than for other substrates.; |
| Catalytic Activity | Oleoyl-[acyl-carrier-protein] + H(2)O = [acyl- carrier-protein] + oleate. {ECO:0000269|PubMed:12061798}. |
| Function | Plays an essential role in chain termination during de novo fatty acid synthesis. Possesses high thioesterase activity for oleoyl-ACP versus other acyl-ACPs. Substrate preference is 18:1 > 18:0 > 16:1. {ECO:0000269|PubMed:12061798, ECO:0000269|PubMed:22002626}. |
| Similarity | Belongs to the acyl-ACP thioesterase family. {ECO:0000305}. |
| Subcellular Location | Plastid, chloroplast {ECO:0000305}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP010705 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 15230256 | RefSeq | NP_189147 | 362 | fatA acyl-ACP thioesterase |
Identical Sequences to LMP010705 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15230256 | DBBJ | BAB02069.1 | 362 | acyl carrier protein thioesterase [Arabidopsis thaliana] |
| GI:15230256 | DBBJ | BAD43868.1 | 362 | acyl-(acyl carrier protein) thioesterase [Arabidopsis thaliana] |
| GI:15230256 | GenBank | AEE76980.1 | 362 | fatA acyl-ACP thioesterase [Arabidopsis thaliana] |
| GI:15230256 | GenBank | AGF22771.1 | 362 | Sequence 67 from patent US 8372610 |
| GI:15230256 | GenBank | AGV92056.1 | 362 | Sequence 208 from patent US 8530221 |
| GI:15230256 | SwissProt | Q42561.1 | 362 | RecName: Full=Oleoyl-acyl carrier protein thioesterase 1, chloroplastic; AltName: Full=18:0-acyl-carrier protein thioesterase; Short=18:0-ACP thioesterase; AltName: Full=Acyl-[acyl-carrier-protein] hydrolase; Flags: Precursor [Arabidopsis thaliana] |
Related Sequences to LMP010705 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15230256 | GenBank | EFH61940.1 | 360 | fata acyl-acp thioesterase [Arabidopsis lyrata subsp. lyrata] |
| GI:15230256 | GenBank | AFQ60946.1 | 368 | chloroplast acyl-ACP thioesterase A [Camelina sativa] |
| GI:15230256 | GenBank | EOA30882.1 | 363 | hypothetical protein CARUB_v10014026mg [Capsella rubella] |
| GI:15230256 | RefSeq | XP_002885681.1 | 360 | fata acyl-acp thioesterase [Arabidopsis lyrata subsp. lyrata] |
| GI:15230256 | RefSeq | XP_006297984.1 | 363 | hypothetical protein CARUB_v10014026mg [Capsella rubella] |
| GI:15230256 | RefSeq | XP_010466931.1 | 368 | PREDICTED: oleoyl-acyl carrier protein thioesterase 1, chloroplastic [Camelina sativa] |