Gene/Proteome Database (LMPD)
LMPD ID
LMP010707
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
fatty acid desaturase 7
Gene Symbol
Synonyms
CHLOROPLAST PRECURSOR; FAD7; FADD; fatty acid desaturase 7; FATTY ACID DESATURASE D; OMEGA-3 FATTY ACID DESATURASE
Alternate Names
fatty acid desaturase 7
Chromosome
3
EC Number
1.14.19.-
Summary
Chloroplastic enzyme responsible for the synthesis of 16:3 and 18:3 fatty acids from galactolipids, sulpholipids and phosphatidylglycerol. Uses ferredoxin as electron donor. Gene expression is induced by wounding in shoot and root. The wound-response in shoot is independent of jasmonic acid mediated pathway whereas the root response is mediated by jasmonic acid.
Orthologs
Proteins
| fatty acid desaturase 7 | |
|---|---|
| Refseq ID | NP_187727 |
| Protein GI | 15229692 |
| UniProt ID | P46310 |
| mRNA ID | NM_111953 |
| Length | 446 |
| RefSeq Status | REVIEWED |
| MANLVLSECGIRPLPRIYTTPRSNFLSNNNKFRPSLSSSSYKTSSSPLSFGLNSRDGFTRNWALNVSTPLTTPIFEESPLEEDNKQRFDPGAPPPFNLADIRAAIPKHCWVKNPWKSLSYVVRDVAIVFALAAGAAYLNNWIVWPLYWLAQGTMFWALFVLGHDCGHGSFSNDPKLNSVVGHLLHSSILVPYHGWRISHRTHHQNHGHVENDESWHPMSEKIYNTLDKPTRFFRFTLPLVMLAYPFYLWARSPGKKGSHYHPDSDLFLPKERKDVLTSTACWTAMAALLVCLNFTIGPIQMLKLYGIPYWINVMWLDFVTYLHHHGHEDKLPWYRGKEWSYLRGGLTTLDRDYGLINNIHHDIGTHVIHHLFPQIPHYHLVEATEAAKPVLGKYYREPDKSGPLPLHLLEILAKSIKEDHYVSDEGEVVYYKADPNLYGEVKVRAD | |
Gene Information
Entrez Gene ID
Gene Name
fatty acid desaturase 7
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0009507 | IDA:TAIR | C | chloroplast |
| GO:0009941 | IDA:TAIR | C | chloroplast envelope |
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0009528 | IEA:UniProtKB-KW | C | plastid inner membrane |
| GO:0042170 | TAS:TAIR | C | plastid membrane |
| GO:0016717 | IEA:InterPro | F | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
| GO:0006633 | IMP:TAIR | P | fatty acid biosynthetic process |
| GO:0009409 | IMP:TAIR | P | response to cold |
| GO:0006636 | IEA:UniProtKB-UniPathway | P | unsaturated fatty acid biosynthetic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ath01040 | Biosynthesis of unsaturated fatty acids |
| ath01212 | Fatty acid metabolism |
BIOCYC Pathway Links
Domain Information
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Domain | The histidine box domains may contain the active site and/or be involved in metal ion binding. |
| Function | Chloroplast omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol. |
| Pathway | Lipid metabolism; polyunsaturated fatty acid biosynthesis. |
| Similarity | Belongs to the fatty acid desaturase family. {ECO:0000305}. |
| Subcellular Location | Plastid, chloroplast inner membrane {ECO:0000269|PubMed:12766230}; Multi-pass membrane protein {ECO:0000269|PubMed:12766230}. |
| Tissue Specificity | Most abundant in leaves and seedlings. |
Identical and Related Proteins
Unique RefSeq proteins for LMP010707 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 15229692 | RefSeq | NP_187727 | 446 | fatty acid desaturase 7 |
Identical Sequences to LMP010707 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15229692 | EMBL | CBD33397.1 | 446 | unnamed protein product [Arabidopsis thaliana] |
| GI:15229692 | EMBL | CBD04730.1 | 446 | unnamed protein product [Arabidopsis thaliana] |
| GI:15229692 | GenBank | ADR85396.1 | 446 | Sequence 71 from patent US 7736884 |
| GI:15229692 | GenBank | ADS39951.1 | 446 | Sequence 10 from patent US 7790959 |
| GI:15229692 | GenBank | AEE75009.1 | 446 | fatty acid desaturase 7 [Arabidopsis thaliana] |
| GI:15229692 | GenBank | AFX49064.1 | 446 | Sequence 50897 from patent US 8299318 |
Related Sequences to LMP010707 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15229692 | GenBank | AAK63867.1 | 446 | AT3g11170/F9F8_4 [Arabidopsis thaliana] |
| GI:15229692 | GenBank | AAM26725.1 | 446 | AT3g11170/F9F8_4 [Arabidopsis thaliana] |
| GI:15229692 | GenBank | EFH58976.1 | 446 | hypothetical protein ARALYDRAFT_478456 [Arabidopsis lyrata subsp. lyrata] |
| GI:15229692 | GenBank | EOA30563.1 | 449 | hypothetical protein CARUB_v10013689mg [Capsella rubella] |
| GI:15229692 | RefSeq | XP_002882717.1 | 446 | hypothetical protein ARALYDRAFT_478456 [Arabidopsis lyrata subsp. lyrata] |
| GI:15229692 | RefSeq | XP_006297665.1 | 449 | hypothetical protein CARUB_v10013689mg [Capsella rubella] |