Gene/Proteome Database (LMPD)

LMPD ID
LMP010760
Gene ID
817175
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
peroxin 10
Gene Symbol
PEX10
Synonyms
ATPEX10; peroxin 10; PEX10; T9J22.2
Alternate Names
peroxin 10
Chromosome
2

Proteins

peroxin 10
Refseq ID NP_565621
Protein GI 18401101
UniProt ID Q9SYU4
mRNA ID NM_128192
Length 381
RefSeq Status REVIEWED
MRLNGDSGPGQDEPGSSGFHGGIRRFPLAAQPEIMRAAEKDDQYASFIHEACRDAFRHLFGTRIALAYQKEMKLLGQMLYYVLTTGSGQQTLGEEYCDIIQVAGPYGLSPTPARRALFILYQTAVPYIAERISTRAATQAVTFDESDEFFGDSHIHSPRMIDLPSSSQVETSTSVVSRLNDRLMRSWHRAIQRWPVVLPVAREVLQLVLRANLMLFYFEGFYYHISKRASGVRYVFIGKQLNQRPRYQILGVFLLIQLCILAAEGLRRSNLSSITSSIQQASIGSYQTSGGRGLPVLNEEGNLITSEAEKGNWSTSDSTSTEAVGKCTLCLSTRQHPTATPCGHVFCWSCIMEWCNEKQECPLCRTPNTHSSLVCLYHSDF

Gene Information

Entrez Gene ID
817175
Gene Name
peroxin 10
Gene Symbol
PEX10
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IDA:TAIR C cytosol
GO:0005779 IEA:InterPro C integral component of peroxisomal membrane
GO:0005777 IDA:TAIR C peroxisome
GO:0004842 IDA:TAIR F ubiquitin-protein transferase activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0010381 IMP:TAIR P attachment of peroxisome to chloroplast
GO:0009793 IMP:TAIR P embryo development ending in seed dormancy
GO:0006635 IMP:TAIR P fatty acid beta-oxidation
GO:0007031 IMP:TAIR P peroxisome organization
GO:0009853 IMP:TAIR P photorespiration
GO:0016558 IMP:TAIR P protein import into peroxisome matrix
GO:0006513 IDA:TAIR P protein monoubiquitination

KEGG Pathway Links

KEGG Pathway ID Description
ath04146 Peroxisome
ko04146 Peroxisome

Domain Information

InterPro Annotations

Accession Description
IPR025654 Peroxisome biogenesis factor 10
IPR006845 Pex, N-terminal
IPR001841 Zinc finger, RING-type
IPR017907 Zinc finger, RING-type, conserved site
IPR013083 Zinc finger, RING/FYVE/PHD-type

UniProt Annotations

Entry Information

Gene Name
peroxin 10
Protein Entry
PEX10_ARATH
UniProt ID
Q9SYU4
Species
Arabidopsis

Comments

Comment Type Description
Cofactor Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000269|PubMed:23336935};
Developmental Stage Increased expression in early post- germinative growth.
Disruption Phenotype Embryo lethality at the heart stage. {ECO:0000269|PubMed:12883010, ECO:0000269|PubMed:14576288, ECO:0000269|PubMed:17215364}.
Function Involved in the formation of peroxisomes, lipid bodies and protein bodies. Required for normal-shaped peroxisomes that can physically associate with the outer membrane of the chloroplast envelope. Not involved in beta-oxidation and glyoxylate cycle. Acts as an E3 ubiquitin-protein ligase. {ECO:0000269|PubMed:12883010, ECO:0000269|PubMed:14576288, ECO:0000269|PubMed:17215364, ECO:0000269|PubMed:17478547, ECO:0000269|PubMed:20679226, ECO:0000269|PubMed:23336935}.
Induction Up-regulated by hydrogen peroxide. {ECO:0000269|PubMed:11118212}.
Interaction Q9SRQ3:PEX19-1; NbExp=2; IntAct=EBI-1151983, EBI-1151789;
Miscellaneous Travels directly from the cytosol to the peroxisomes.
Sequence Caution Sequence=AAM14959.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the pex2/pex10/pex12 family. {ECO:0000305}.
Similarity Contains 1 RING-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00175}.
Subcellular Location Peroxisome {ECO:0000269|PubMed:14576288, ECO:0000269|PubMed:16169966}. Peroxisome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Subunit Interacts (via C-terminus) with PEX19-1. {ECO:0000269|PubMed:16923726}.
Tissue Specificity Expressed in roots, stems, leaves, flowers and siliques. {ECO:0000269|PubMed:14576288}.
Web Resource Name=PlantsUBQ; Note=A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants; URL="http://plantsubq.genomics.purdue.edu/";

Identical and Related Proteins

Unique RefSeq proteins for LMP010760 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18401101 RefSeq NP_565621 381 peroxin 10

Identical Sequences to LMP010760 proteins

Reference Database Accession Length Protein Name
GI:18401101 EMBL CCF77182.1 381 unnamed protein product [Arabidopsis thaliana]
GI:18401101 GenBank AEC07828.1 381 peroxin 10 [Arabidopsis thaliana]
GI:18401101 GenBank AEQ40483.1 381 Sequence 1044 from patent US 8030546
GI:18401101 GenBank AFC08186.1 381 Sequence 298 from patent US 8110725
GI:18401101 GenBank AGM80172.1 381 Sequence 298 from patent US 8426678
GI:18401101 GenBank AGM82870.1 381 Sequence 46 from patent US 8426685

Related Sequences to LMP010760 proteins

Reference Database Accession Length Protein Name
GI:18401101 EMBL CAB87983.1 381 Pex10p [Arabidopsis thaliana]
GI:18401101 GenBank AAM64667.1 381 putative peroxisome assembly protein PER8 [Arabidopsis thaliana]
GI:18401101 GenBank EFH57037.1 388 hypothetical protein ARALYDRAFT_481492 [Arabidopsis lyrata subsp. lyrata]
GI:18401101 RefSeq XP_002880778.1 388 hypothetical protein ARALYDRAFT_481492 [Arabidopsis lyrata subsp. lyrata]
GI:18401101 RefSeq XP_010417423.1 385 PREDICTED: peroxisome biogenesis factor 10-like [Camelina sativa]
GI:18401101 RefSeq XP_010472664.1 385 PREDICTED: peroxisome biogenesis factor 10 [Camelina sativa]