Gene/Proteome Database (LMPD)

LMPD ID
LMP010767
Gene ID
839315
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
peroxisome biogenesis protein 6
Gene Symbol
PEX6
Synonyms
F10O3.18; F10O3_18; peroxin 6; PEX6
Alternate Names
peroxisome biogenesis protein 6
Chromosome
1
Summary
Encodes an apparent ATPase similar to yeast and human protein required for peroxisomal biogenesis. May facilitate recycling of PEX5, the peroxisomal matrix protein receptor, and thereby promote peroxisomal matrix protein import.
Orthologs
View orthologs and multiple alignments for PEX6

Proteins

peroxisome biogenesis protein 6
Refseq ID NP_171799
Protein GI 22329309
UniProt ID Q8RY16
mRNA ID NM_100181
Length 941
RefSeq Status REVIEWED
MVERRNPLVLSSTRSTLRSVLNSSQPSSADGDRVLNKDGDLLRGNARLSAGILRWRKDGENVSDAKLDSLDDSALVGLSTQLLKRLSINSGSLVVVKNIEIGIQRVAQVVVLDPPKTTLEDASLTQVPVSDSLHTMLVFPTYDLMGQQLLDQEVAYLSPMLAFNLSLHISCLKSLVHRGNGVLEKYFEAKCDEEFIGKSAEDGSKIGLDLEPVSQVPGYASHLRVSFVKIPECGTIPSLKVNSSFEAEERQGLIDSALQKYFGTDRQLSRGDIFRIYIDWNCGSSICNPCSQRLCSESDDYIYFKVIAMEPSNERFLRVNHSQTALVLGGTVSSGLPPDLLVYRSKVPMPLQEETVNILASVLSPPLCPSALASKLRVAVLLHGIPGCGKRTVVKYVARRLGLHVVEFSCHSLLASSERKTSTALAQTFNMARRYSPTILLLRHFDVFKNLGSQDGSLGDRVGVSFEIASVIRELTEPVSNGDSSMEEKSNSNFSENEVGKFRGHQVLLIASAESTEGISPTIRRCFSHEIRMGSLNDEQRSEMLSQSLQGVSQFLNISSDEFMKGLVGQTSGFLPRDLQALVADAGANLYISQESETKKINSLSDDLHGVDIHQASQIDNSTEKLTAKEDFTKALDRSKKRNASALGAPKVPNVKWDDVGGLEDVKTSILDTVQLPLLHKDLFSSGLRKRSGVLLYGPPGTGKTLLAKAVATECSLNFLSVKGPELINMYIGESEKNVRDIFEKARSARPCVIFFDELDSLAPARGASGDSGGVMDRVVSQMLAEIDGLSDSSQDLFIIGASNRPDLIDPALLRPGRFDKLLYVGVNADASYRERVLKALTRKFKLSEDVSLYSVAKKCPSTFTGADMYALCADAWFQAAKRKVSKSDSGDMPTEEDDPDSVVVEYVDFIKAMDQLSPSLSITELKKYEMLRDQFQGRSS

Gene Information

Entrez Gene ID
839315
Gene Name
peroxisome biogenesis protein 6
Gene Symbol
PEX6
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0006635 IMP:TAIR P fatty acid beta-oxidation
GO:0016558 IMP:TAIR P protein import into peroxisome matrix

KEGG Pathway Links

KEGG Pathway ID Description
ath04146 Peroxisome
ko04146 Peroxisome

Domain Information

InterPro Annotations

Accession Description
IPR003593 AAA+ ATPase domain
IPR003960 ATPase, AAA-type, conserved site
IPR003959 ATPase, AAA-type, core
IPR027417 P-loop containing nucleoside triphosphate hydrolase

UniProt Annotations

Entry Information

Gene Name
peroxisome biogenesis protein 6
Protein Entry
PEX6_ARATH
UniProt ID
Q8RY16
Species
Arabidopsis

Comments

Comment Type Description
Function Involved in peroxisomal-targeting signal one (PTS1) and peroxisomal-targeting signal two (PTS2) protein import. Required for jasmonate biosynthesis. Necessary for the developmental elimination of obsolete peroxisome matix proteins. May form heteromeric AAA ATPase complexes required for the import of proteins. May be involved in PEX5 recycling. {ECO:0000269|PubMed:14745029, ECO:0000269|PubMed:17478547, ECO:0000269|PubMed:17544464, ECO:0000269|PubMed:19246395, ECO:0000269|PubMed:20969679}.
Sequence Caution Sequence=AAD25809.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the AAA ATPase family. {ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000250}.
Subunit May form a AAA complex with PEX1. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010767 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
22329309 RefSeq NP_171799 941 peroxisome biogenesis protein 6

Identical Sequences to LMP010767 proteins

Reference Database Accession Length Protein Name
GI:22329309 EMBL CBC76323.1 941 unnamed protein product [Arabidopsis thaliana]
GI:22329309 EMBL CBC65111.1 941 unnamed protein product [Arabidopsis thaliana]
GI:22329309 EMBL CBC87042.1 941 unnamed protein product [Arabidopsis thaliana]
GI:22329309 EMBL CBC71072.1 941 unnamed protein product [Arabidopsis thaliana]
GI:22329309 EMBL CBC51710.1 941 unnamed protein product [Arabidopsis thaliana]
GI:22329309 GenBank AEE27513.1 941 peroxisome biogenesis protein 6 [Arabidopsis thaliana]

Related Sequences to LMP010767 proteins

Reference Database Accession Length Protein Name
GI:22329309 EMBL CAW66705.1 983 unnamed protein product [Arabidopsis thaliana]
GI:22329309 EMBL CAW52307.1 983 unnamed protein product [Arabidopsis thaliana]
GI:22329309 EMBL CAW53442.1 983 unnamed protein product [Arabidopsis thaliana]
GI:22329309 EMBL CAW48903.1 983 unnamed protein product [Arabidopsis thaliana]
GI:22329309 EMBL CAW69839.1 983 unnamed protein product [Arabidopsis thaliana]
GI:22329309 EMBL CAW60180.1 983 unnamed protein product [Arabidopsis thaliana]