Gene/Proteome Database (LMPD)
LMPD ID
LMP010780
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phosphatidylcholine:diacylglycerol cholinephosphotransferase
Gene Symbol
Synonyms
REDUCED OLEATE DESATURATION 1; ROD1
Alternate Names
phosphatidylcholine:diacylglycerol cholinephosphotransferase
Chromosome
3
EC Number
2.7.8.-
Summary
Functions as phosphatidylcholine:diacylglycerol cholinephosphotransferase, a major reaction for the transfer of 18:1 into phosphatidylcholine for desaturation and also for the reverse transfer of 18:2 and 18:3 into the triacylglycerols synthesis pathway
Orthologs
Proteins
| phosphatidylcholine:diacylglycerol cholinephosphotransferase | |
|---|---|
| Refseq ID | NP_566527 |
| Protein GI | 18400910 |
| UniProt ID | Q9LVZ7 |
| mRNA ID | NM_112452 |
| Length | 301 |
| RefSeq Status | REVIEWED |
| MSAAAAETDVSLRRRSNSLNGNHTNGVAIDGTLDNNNRRVGDTNTHMDISAKKTDNGYANGVGGGGWRSKASFTTWTARDIVYVVRYHWIPCMFAAGLLFFMGVEYTLQMIPARSEPFDLGFVVTRSLNRVLASSPDLNTVLAALNTVFVGMQTTYIVWTWLVEGRARATIAALFMFTCRGILGYSTQLPLPQDFLGSGVDFPVGNVSFFLFFSGHVAGSMIASLDMRRMQRLRLAMVFDILNVLQSIRLLGTRGHYTIDLAVGVGAGILFDSLAGKYEEMMSKRHLGTGFSLISKDSLVN | |
Gene Information
Entrez Gene ID
Gene Name
phosphatidylcholine:diacylglycerol cholinephosphotransferase
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0004142 | IDA:TAIR | F | diacylglycerol cholinephosphotransferase activity |
| GO:0006657 | IDA:GOC | P | CDP-choline pathway |
| GO:0046470 | IMP:TAIR | P | phosphatidylcholine metabolic process |
BIOCYC Pathway Links
Domain Information
InterPro Annotations
| Accession | Description |
|---|
UniProt Annotations
Entry Information
Gene Name
phosphatidylcholine:diacylglycerol cholinephosphotransferase
Protein Entry
PDCT1_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Biophysicochemical Properties | Kinetic parameters: Vmax=4.5 nmol/min/mg enzyme with phosphatidylcholine as substrate (at 23 degrees Celsius) {ECO:0000269|PubMed:19833868}; pH dependence: Optimum pH is 6.5-7 at 23 degrees Celsius. {ECO:0000269|PubMed:19833868}; |
| Biophysicochemical Properties | Kinetic parameters: Vmax=4.5 nmol/min/mg enzyme with phosphatidylcholine as substrate (at 23 degrees Celsius) {ECO:0000269|PubMed:19833868}; pH dependence: Optimum pH is 6.5-7 at 23 degrees Celsius. {ECO:0000269|PubMed:19833868}; |
| Disruption Phenotype | Reduction by 40 percents of 18:2 and 18:3 triacylglycerols (TAG) accumulation in seeds. {ECO:0000269|PubMed:19833868, ECO:0000269|PubMed:22932756}. |
| Function | Functions as phosphatidylcholine:diacylglycerol cholinephosphotransferase that catalyzes the transfer of the phosphocholine headgroup from phosphatidylcholine (PC) to diacylglycerol, a major reaction for the transfer of 18:1 into phosphatidylcholine for desaturation and also for the reverse transfer of 18:2 and 18:3 into the triacylglycerols synthesis pathway. {ECO:0000269|PubMed:19833868, ECO:0000269|PubMed:22371508, ECO:0000269|PubMed:22932756}. |
| Sequence Caution | Sequence=AAK49592.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; |
| Similarity | Belongs to the phosphatidylcholine:diacylglycerol cholinephosphotransferase family. {ECO:0000305}. |
| Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP010780 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 18400910 | RefSeq | NP_566527 | 301 | phosphatidylcholine:diacylglycerol cholinephosphotransferase |
Identical Sequences to LMP010780 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:18400910 | DBBJ | BAB02313.1 | 301 | unnamed protein product [Arabidopsis thaliana] |
| GI:18400910 | GenBank | AAM63365.1 | 301 | unknown [Arabidopsis thaliana] |
| GI:18400910 | GenBank | AEE75730.1 | 301 | phosphatidylcholine:diacylglycerol cholinephosphotransferase [Arabidopsis thaliana] |
| GI:18400910 | SwissProt | Q9LVZ7.1 | 301 | RecName: Full=Phosphatidylcholine:diacylglycerol cholinephosphotransferase 1; Short=AtPDCT1; AltName: Full=Protein REDUCED OLEATE DESATURATION 1 [Arabidopsis thaliana] |
Related Sequences to LMP010780 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:18400910 | GenBank | AAK49592.1 | 255 | AT3g15820/MSJ11_22 [Arabidopsis thaliana] |
| GI:18400910 | GenBank | AAO42798.1 | 255 | At3g15820/MSJ11_22 [Arabidopsis thaliana] |
| GI:18400910 | GenBank | EFH59224.1 | 301 | hypothetical protein ARALYDRAFT_897881 [Arabidopsis lyrata subsp. lyrata] |
| GI:18400910 | RefSeq | XP_002882965.1 | 301 | hypothetical protein ARALYDRAFT_897881 [Arabidopsis lyrata subsp. lyrata] |
| GI:18400910 | RefSeq | XP_010503493.1 | 324 | PREDICTED: phosphatidylcholine:diacylglycerol cholinephosphotransferase 1-like [Camelina sativa] |
| GI:18400910 | RefSeq | XP_010487422.1 | 297 | PREDICTED: phosphatidylcholine:diacylglycerol cholinephosphotransferase 1-like [Camelina sativa] |