Gene/Proteome Database (LMPD)
LMPD ID
LMP010802
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phosphatidylinositol-4-phosphate 5-kinase 5
Gene Symbol
Synonyms
phosphatidylinositol- 4-phosphate 5-kinase 5; PIP5K5; T3K9.2; T3K9_2
Alternate Names
phosphatidylinositol-4-phosphate 5-kinase 5
Chromosome
2
EC Number
2.7.1.68
Summary
Encodes a protein with phosphatidylinositol-4-phosphate 5-kinase activity that plays a role in pollen tip growth. The enzyme localizes to the apical plasma membrane and adjacent cytosolic region of pollen tubes. Overexpression of this gene leads to increased deposition of pectin in the cell wall at the tip of the pollen tube and causes altered pollen tube morphology.
Orthologs
Proteins
| phosphatidylinositol-4-phosphate 5-kinase 5 | |
|---|---|
| Refseq ID | NP_181654 |
| Protein GI | 15227305 |
| UniProt ID | Q9SLG9 |
| mRNA ID | NM_129686 |
| Length | 772 |
| RefSeq Status | REVIEWED |
| MSKDQSYVLKAWEVTVRKTQQAKKRANSVFGTVSVAPHTDNDTTTDDNDDETTTNRSSLEEFYHAERVLPNGDYYTGQWYDSFPHGHGKYLWTDGCMYIGDWYNGKTMGNGKFGWPSGATYEGEFKSGYMDGIGTYTGPSGDAYKGQWVMNLKHGHGVKSFANGDAYDGEWRRGLQEGQGKYQWSDGSYYIGEWKNGTICGKGSFVWTNGNRYDGFWDEGFPRGNGTFKWDNGSFYVGHWSKDPEEMNGTYYPSGNEGNLEWDPKDLFNNLSEYTICSGERVPTLPSQKKLSVWNSSKRIEKPRRTSVDGRVSVGVDRAFEKMNMWGNEIGEGGADMRKELDAELMRLDAEGLQSLKSSPVPMKLPKAGRKQGETISKGHRNYELMLNLQLGIRHSVGRQAPAASLDLKPSAFDPKDKIWRRFPREGTKYTPPHQSTEFKWKDYCPLVFRSLRKLFKVDPADYMLSICGNDALRELSSPGKSGSFFYLTNDDRYMIKTMKKSETKVLLGMLAAYYNHVRAFENSLVIRFFGLHCVKLNGPTQKKVRFVIMGNLFCSKYSVHRRFDLKGSSLGRTTDKPESEIDSNTILKDLDLNFIFRLQKAWYQEFIRQIDKDCEFLEQERIMDYSLLVGIHFREASVAGELIPSGARTPIGESEEESGPRLSRAEVDELLSDPSRWASIRLGTNMPARAERTMRKNDSELQLVGEPTGEFYEVVMIFGIIDILQDYDISKKLEHAYKSIQYDPSSISAVDPRQYSRRFRDFIFKVFTDDN | |
Gene Information
Entrez Gene ID
Gene Name
phosphatidylinositol-4-phosphate 5-kinase 5
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0016324 | IDA:TAIR | C | apical plasma membrane |
| GO:0005829 | IDA:TAIR | C | cytosol |
| GO:0090406 | IDA:TAIR | C | pollen tube |
| GO:0016308 | IDA:TAIR | F | 1-phosphatidylinositol-4-phosphate 5-kinase activity |
| GO:0005524 | IEA:UniProtKB-KW | F | ATP binding |
| GO:0046488 | IDA:TAIR | P | phosphatidylinositol metabolic process |
| GO:0046854 | IDA:GOC | P | phosphatidylinositol phosphorylation |
| GO:0009827 | IMP:TAIR | P | plant-type cell wall modification |
| GO:0009846 | IGI:TAIR | P | pollen germination |
| GO:0009860 | IGI:TAIR | P | pollen tube growth |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ath04144 | Endocytosis |
| ath00562 | Inositol phosphate metabolism |
| ath01100 | Metabolic pathways |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 6254333 | Synthesis of PIPs at the plasma membrane |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR003409 | MORN motif |
| IPR023610 | Phosphatidylinositol-4-phosphate 5-kinase |
| IPR027483 | Phosphatidylinositol-4-phosphate 5-kinase, C-terminal |
| IPR027484 | Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain |
| IPR002498 | Phosphatidylinositol-4-phosphate 5-kinase, core |
| IPR016034 | Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup |
| IPR017163 | Phosphatidylinositol-4-phosphate 5-kinase, plant |
UniProt Annotations
Entry Information
Gene Name
phosphatidylinositol-4-phosphate 5-kinase 5
Protein Entry
PI5K5_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | ATP + 1-phosphatidyl-1D-myo-inositol 4- phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. |
| Similarity | Contains 1 PIPK domain. {ECO:0000255|PROSITE- ProRule:PRU00781}. |
| Similarity | Contains 8 MORN repeats. {ECO:0000305}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP010802 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 15227305 | RefSeq | NP_181654 | 772 | phosphatidylinositol-4-phosphate 5-kinase 5 |
Identical Sequences to LMP010802 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15227305 | GenBank | AAK49397.1 | 772 | phosphatidylinositol-4-phosphate 5-kinase [Arabidopsis thaliana] |
| GI:15227305 | GenBank | AAM14925.1 | 772 | putative phosphatidylinositol-4-phosphate 5-kinase [Arabidopsis thaliana] |
| GI:15227305 | GenBank | AEC09944.1 | 772 | phosphatidylinositol-4-phosphate 5-kinase 5 [Arabidopsis thaliana] |
| GI:15227305 | SwissProt | Q9SLG9.1 | 772 | RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase 5; Short=AtPIP5K5; AltName: Full=1-phosphatidylinositol 4-phosphate kinase 5; AltName: Full=Diphosphoinositide kinase 5; AltName: Full=PtdIns(4)P-5-kinase 5 [Arabidopsis thaliana] |
Related Sequences to LMP010802 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15227305 | GenBank | EFH56174.1 | 772 | phosphatidylinositol-4-phosphate 5-kinase family protein [Arabidopsis lyrata subsp. lyrata] |
| GI:15227305 | GenBank | EOA28546.1 | 772 | hypothetical protein CARUB_v10024770mg [Capsella rubella] |
| GI:15227305 | RefSeq | XP_002879915.1 | 772 | phosphatidylinositol-4-phosphate 5-kinase family protein [Arabidopsis lyrata subsp. lyrata] |
| GI:15227305 | RefSeq | XP_006295648.1 | 772 | hypothetical protein CARUB_v10024770mg [Capsella rubella] |
| GI:15227305 | RefSeq | XP_010505886.1 | 772 | PREDICTED: phosphatidylinositol 4-phosphate 5-kinase 5-like [Camelina sativa] |
| GI:15227305 | RefSeq | XP_010517609.1 | 772 | PREDICTED: phosphatidylinositol 4-phosphate 5-kinase 5 [Camelina sativa] |