Gene/Proteome Database (LMPD)

LMPD ID
LMP010821
Gene ID
824569
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phosphatidylinositol:ceramide inositolphosphotransferase 1
Gene Symbol
AtIPCS1
Synonyms
Arabidopsis Inositol phosphorylceramide synthase 1; AtIPCS1
Alternate Names
phosphatidylinositol:ceramide inositolphosphotransferase 1
Chromosome
3
EC Number
2.7.8.-
Summary
Inositol phosphorylceramide synthase
Orthologs
View orthologs and multiple alignments for AtIPCS1

Proteins

phosphatidylinositol:ceramide inositolphosphotransferase 1
Refseq ID NP_190970
Protein GI 15232394
UniProt ID Q9M325
mRNA ID NM_115262
Length 305
RefSeq Status REVIEWED
MTLYIRREASKLWRRFCSEITTEIGLLAENWKYLLAGLLCQYIHGLAARGVHYIHRPGPTLQDSGFFVLPELGQDKGFISETVFTCVFLSFFLWTFHPFIVKSKKIYTVLIWCRVLAFLVACQFLRVITFYSTQLPGPNYHCREGSELARLPRPHNVLEVLLLNFPRGVIYGCGDLIFSSHMIFTLVFVRTYQKYGSKRFIKLLGWVIAILQSLLIIASRKHYTVDVVVAWYTVNLVVFFLDKKLPELPDRTTALLPVISKDRTKEESHKLLNGNGVDPADRRPRAQVNGKDSNGGHTDNATNGT

Gene Information

Entrez Gene ID
824569
Gene Name
phosphatidylinositol:ceramide inositolphosphotransferase 1
Gene Symbol
AtIPCS1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0045140 IDA:TAIR F inositol phosphoceramide synthase activity
GO:0030148 IDA:TAIR P sphingolipid biosynthetic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5129 sphingolipid biosynthesis (plants)

Domain Information

InterPro Annotations

Accession Description
IPR025749 Sphingomyelin synthase-like domain

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol:ceramide inositolphosphotransferase 1
Protein Entry
IPCS1_ARATH
UniProt ID
Q9M325
Species
Arabidopsis

Comments

Comment Type Description
Function Catalyzes the transfer of the phosphorylinositol group from phosphatidylinositol (PI) to phytoceramide, an essential step in sphingolipid biosynthesis. {ECO:0000269|PubMed:20309609}.
Similarity Belongs to the sphingomyelin synthase family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed at low levels in roots, leaves, stems, flowers and siliques. {ECO:0000269|PubMed:20309609}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010821 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15232394 RefSeq NP_190970 305 phosphatidylinositol:ceramide inositolphosphotransferase 1

Identical Sequences to LMP010821 proteins

Reference Database Accession Length Protein Name
GI:15232394 EMBL CAW93368.1 305 unnamed protein product [Arabidopsis thaliana]
GI:15232394 EMBL CBD12189.1 305 unnamed protein product [Arabidopsis thaliana]
GI:15232394 EMBL CBC95353.1 305 unnamed protein product [Arabidopsis thaliana]
GI:15232394 EMBL CBD02144.1 305 unnamed protein product [Arabidopsis thaliana]
GI:15232394 EMBL CBC92958.1 305 unnamed protein product [Arabidopsis thaliana]
GI:15232394 GenBank AEE79176.1 305 phosphatidylinositol:ceramide inositolphosphotransferase 1 [Arabidopsis thaliana]

Related Sequences to LMP010821 proteins

Reference Database Accession Length Protein Name
GI:15232394 GenBank EFH52495.1 305 hypothetical protein ARALYDRAFT_906800 [Arabidopsis lyrata subsp. lyrata]
GI:15232394 GenBank EOA25642.1 305 hypothetical protein CARUB_v10018990mg [Capsella rubella]
GI:15232394 RefSeq XP_002876236.1 305 hypothetical protein ARALYDRAFT_906800 [Arabidopsis lyrata subsp. lyrata]
GI:15232394 RefSeq XP_006292744.1 305 hypothetical protein CARUB_v10018990mg [Capsella rubella]
GI:15232394 RefSeq XP_010504191.1 305 PREDICTED: phosphatidylinositol:ceramide inositolphosphotransferase 1 [Camelina sativa]
GI:15232394 RefSeq XP_010427066.1 305 PREDICTED: phosphatidylinositol:ceramide inositolphosphotransferase 1-like [Camelina sativa]