Gene/Proteome Database (LMPD)

LMPD ID
LMP010831
Gene ID
828703
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phosphatidylserine decarboxylase 3
Gene Symbol
PSD3
Synonyms
F20B18.80; F20B18_80; phosphatidylserine decarboxylase 3; PSD3
Alternate Names
phosphatidylserine decarboxylase 3
Chromosome
4
EC Number
4.1.1.65
Summary
Encodes the major form of the two non-mitochondrail phosphatidylserine decarboxylase. Located at the ER.
Orthologs
View orthologs and multiple alignments for PSD3

Proteins

phosphatidylserine decarboxylase 3
Refseq ID NP_567736
Protein GI 186513660
UniProt ID A4GNA8
mRNA ID NM_118730
Length 635
RefSeq Status REVIEWED
MGNGNSTETKESRRSKMRKKIQNFRSRRRLSRPGSGSVSGLASQRSVSADDFAGIALLTLIGAEMKFKDKWLACVSFGEQTFRSEISDSTEKPIWNSEKKLLLEKNGPSLARISVFETNRLLKNNIVGYCELDLLDFVVQEPDSTCKSFDLLDPASSNVVGSMFVSCSVEDPVETETCFAKRILSIVDYDEDGKLSFSEFSDLMNAFGNVVAANKKEELFKAADLNGDGVVTIDELAALLAVQQEQEPIINSCPVCGEALQLDKLNAMIHMTLCFDEGTGNQMTGGFLTDRQASYGWMFKLSEWTHLSTYDVGLNTGSSASHIVVIDRKTKRLVEELIDSKIVMSMRAIYQSKIGLRLMDQGAKEILQNLSEKQGKKMNSVESAQNIPSFLEFFKDQINMAEVKYPLDHFKTFNEFFVRELKPGARPIACMDQDDVAVSAADCRLMAFQSVDDSTRFWIKGRKFSIKGLLGNDVQSDAFLDGSLVIFRLAPQDYHRFHSPVSGVIEKFVNVSGSLYTVNPIAVNSKYCNVFTENKRTIVIISTAEFGKVAFVAIGATMVGSISFVRQEGDHVKKGDELGYFSFGGSTVICVFEKDSIKIDEDLLANSARSLETLVTVGMQLGVSFPKLENCVLEP

Gene Information

Entrez Gene ID
828703
Gene Name
phosphatidylserine decarboxylase 3
Gene Symbol
PSD3
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004609 IDA:TAIR F phosphatidylserine decarboxylase activity
GO:0006646 IEA:UniProtKB-UniPathway P phosphatidylethanolamine biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00564 Glycerophospholipid metabolism
ath01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5669 phosphatidylethanolamine biosynthesis I
PHOSLIPSYN2-PWY phospholipid biosynthesis II

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR018247 EF-Hand 1, calcium-binding site
IPR002048 EF-hand domain
IPR011992 EF-hand domain pair
IPR003817 Phosphatidylserine decarboxylase-related

UniProt Annotations

Entry Information

Gene Name
phosphatidylserine decarboxylase 3
Protein Entry
PSD3_ARATH
UniProt ID
A4GNA8
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Phosphatidyl-L-serine = phosphatidylethanolamine + CO(2).
Cofactor Name=pyruvoyl group; Xref=ChEBI:CHEBI:45360; Evidence={ECO:0000250};
Disruption Phenotype No visible phenotype under normal growth conditions. {ECO:0000269|PubMed:17449644}.
Function Catalyzes the biosynthesis of phosphatidylethanolamine (PE) from phosphatidylserine. Contributes only to a minor proportion of PE production. {ECO:0000269|PubMed:17449644}.
Pathway Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.
Sequence Caution Sequence=CAB39662.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB79452.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the phosphatidylserine decarboxylase family. {ECO:0000305}.
Similarity Contains 2 EF-hand domains. {ECO:0000255|PROSITE- ProRule:PRU00448}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305|PubMed:17449644}; Peripheral membrane protein {ECO:0000305|PubMed:17449644}.
Tissue Specificity Expressed in roots, leaves, stems and flowers. {ECO:0000269|PubMed:17449644}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010831 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
186513660 RefSeq NP_567736 635 phosphatidylserine decarboxylase 3

Identical Sequences to LMP010831 proteins

Reference Database Accession Length Protein Name
GI:186513660 GenBank ABO26297.1 635 phosphatidylserine decarboxylase [Arabidopsis thaliana]
GI:186513660 GenBank ADT59622.1 635 Sequence 134 from patent US 7847156
GI:186513660 GenBank AEE85138.1 635 phosphatidylserine decarboxylase 3 [Arabidopsis thaliana]
GI:186513660 SwissProt A4GNA8.1 635 RecName: Full=Phosphatidylserine decarboxylase proenzyme 3; Contains: RecName: Full=Phosphatidylserine decarboxylase 3 beta chain; Contains: RecName: Full=Phosphatidylserine decarboxylase 3 alpha chain [Arabidopsis thaliana]

Related Sequences to LMP010831 proteins

Reference Database Accession Length Protein Name
GI:186513660 GenBank EFH45897.1 636 phosphatidylserine decarboxylase [Arabidopsis lyrata subsp. lyrata]
GI:186513660 RefSeq XP_002869638.1 636 phosphatidylserine decarboxylase [Arabidopsis lyrata subsp. lyrata]
GI:186513660 RefSeq XP_006285267.1 637 hypothetical protein CARUB_v10006639mg [Capsella rubella]
GI:186513660 RefSeq XP_010433568.1 635 PREDICTED: phosphatidylserine decarboxylase proenzyme 3-like [Camelina sativa]
GI:186513660 RefSeq XP_010438816.1 635 PREDICTED: phosphatidylserine decarboxylase proenzyme 3 [Camelina sativa]
GI:186513660 RefSeq XP_010448343.1 635 PREDICTED: phosphatidylserine decarboxylase proenzyme 3 [Camelina sativa]