Gene/Proteome Database (LMPD)

LMPD ID
LMP010846
Gene ID
819999
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phosphoinositide phospholipase C 2
Gene Symbol
PLC2
Synonyms
ATPLC2; phospholipase C 2; PLC2
Chromosome
3
Summary
Phosphoinositide-specific phospholipase C (PI-PLC), catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate into inositol 1,4,5-trisphosphate and diacylglycerol.
Orthologs
View orthologs and multiple alignments for PLC2

Proteins

phosphoinositide phospholipase C 2
Refseq ID NP_001154596
Protein GI 238479688
UniProt ID F4IX90
mRNA ID NM_001161124
Length 552
RefSeq Status REVIEWED
MSKQTYKVCFCFRRRFRYTASEAPREIKTIFEKYSENGVMTVDHLHRFLIDVQKQDKATREDAQSIINSASSLLHRNGLHLDAFFKYLFGDNNPPLALHKVHHDMDAPISHYFIFTGHNSYLTGNQLSSDCSEVPIIDALKKGVRVIELDIWPNSNKDDIDVLHGMTLTTPVGLIKCLKAIRAHAFDVSDYPVVVTLEDHLTPDLQSKVAEMVTEIFGEILFTPPVGESLKEFPSPNSLKRRIIISTKPPKEYKEGKDVEVVQKGKDLGDEEVWGREVPSFIQRNKSEAKDDLDGNDDDDDDDDEDKSKINAPPQYKHLIAIHAGKPKGGITECLKVDPDKVRRLSLSEEQLEKAAEKYAKQIVRFTQHNLLRIYPKGTRVTSSNYNPLVGWSHGAQMVAFNMQGYGRSLWLMQGMFRANGGCGYIKKPDLLLKSGSDSDIFDPKATLPVKTTLRVGIAGVPGDTVMKKTKTLEDNWIPAWDEVFEFPLTVPELALLRLEVHEYDMSEKDDFGGQTCLPVWELSEGIRAFPLHSRKGEKYKSVKLLVKVEFV
phosphoinositide phospholipase C 2
Refseq ID NP_001030660
Protein GI 79313161
UniProt ID Q39033
mRNA ID NM_001035583
Length 581
RefSeq Status REVIEWED
MSKQTYKVCFCFRRRFRYTASEAPREIKTIFEKYSENGVMTVDHLHRFLIDVQKQDKATREDAQSIINSASSLLHRNGLHLDAFFKYLFGDNNPPLALHKVHHDMDAPISHYFIFTGHNSYLTGNQLSSDCSEVPIIDALKKGVRVIELDIWPNSNKDDIDVLHGMTLTTPVGLIKCLKAIRAHAFDVSDYPVVVTLEDHLTPDLQSKVAEMVTEIFGEILFTPPVGESLKEFPSPNSLKRRIIISTKPPKEYKEGKDVEVVQKGKDLGDEEVWGREVPSFIQRNKSEAKDDLDGNDDDDDDDDEDKSKINAPPQYKHLIAIHAGKPKGGITECLKVDPDKVRRLSLSEEQLEKAAEKYAKQIVRFTQHNLLRIYPKGTRVTSSNYNPLVGWSHGAQMVAFNMQGYGRSLWLMQGMFRANGGCGYIKKPDLLLKSGSDSDIFDPKATLPVKTTLRVTVYMGEGWYFDFRHTHFDQYSPPDFYTRVGIAGVPGDTVMKKTKTLEDNWIPAWDEVFEFPLTVPELALLRLEVHEYDMSEKDDFGGQTCLPVWELSEGIRAFPLHSRKGEKYKSVKLLVKVEFV
phosphoinositide phospholipase C 2
Refseq ID NP_187464
Protein GI 15231929
UniProt ID Q39033
mRNA ID NM_111686
Length 581
RefSeq Status REVIEWED
MSKQTYKVCFCFRRRFRYTASEAPREIKTIFEKYSENGVMTVDHLHRFLIDVQKQDKATREDAQSIINSASSLLHRNGLHLDAFFKYLFGDNNPPLALHKVHHDMDAPISHYFIFTGHNSYLTGNQLSSDCSEVPIIDALKKGVRVIELDIWPNSNKDDIDVLHGMTLTTPVGLIKCLKAIRAHAFDVSDYPVVVTLEDHLTPDLQSKVAEMVTEIFGEILFTPPVGESLKEFPSPNSLKRRIIISTKPPKEYKEGKDVEVVQKGKDLGDEEVWGREVPSFIQRNKSEAKDDLDGNDDDDDDDDEDKSKINAPPQYKHLIAIHAGKPKGGITECLKVDPDKVRRLSLSEEQLEKAAEKYAKQIVRFTQHNLLRIYPKGTRVTSSNYNPLVGWSHGAQMVAFNMQGYGRSLWLMQGMFRANGGCGYIKKPDLLLKSGSDSDIFDPKATLPVKTTLRVTVYMGEGWYFDFRHTHFDQYSPPDFYTRVGIAGVPGDTVMKKTKTLEDNWIPAWDEVFEFPLTVPELALLRLEVHEYDMSEKDDFGGQTCLPVWELSEGIRAFPLHSRKGEKYKSVKLLVKVEFV

Gene Information

Entrez Gene ID
819999
Gene Name
phosphoinositide phospholipase C 2
Gene Symbol
PLC2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR011992 EF-hand domain pair
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like

UniProt Annotations

Entry Information

Gene Name
phosphoinositide phospholipase C 2
Protein Entry
PLCD2_ARATH
UniProt ID
Q39033
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP010846 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
79313161 RefSeq NP_001030660 581 phosphoinositide phospholipase C 2
15231929 RefSeq NP_187464 581 phosphoinositide phospholipase C 2
238479688 RefSeq NP_001154596 552 phosphoinositide phospholipase C 2

Identical Sequences to LMP010846 proteins

Reference Database Accession Length Protein Name
GI:15231929 EMBL CBU87769.1 581 unnamed protein product [Arabidopsis thaliana]
GI:79313161 EMBL CBU87769.1 581 unnamed protein product [Arabidopsis thaliana]
GI:15231929 EMBL CBU96716.1 581 unnamed protein product [Arabidopsis thaliana]
GI:79313161 EMBL CBU96716.1 581 unnamed protein product [Arabidopsis thaliana]
GI:15231929 GenBank AEE74640.1 581 phosphoinositide phospholipase C 2 [Arabidopsis thaliana]
GI:79313161 GenBank AEE74640.1 581 phosphoinositide phospholipase C 2 [Arabidopsis thaliana]
GI:15231929 GenBank AEE74641.1 581 phosphoinositide phospholipase C 2 [Arabidopsis thaliana]
GI:79313161 GenBank AEE74641.1 581 phosphoinositide phospholipase C 2 [Arabidopsis thaliana]
GI:238479688 GenBank AEE74642.1 552 phosphoinositide phospholipase C 2 [Arabidopsis thaliana]
GI:15231929 GenBank AGX54704.1 581 Sequence 9764 from patent US 8541208
GI:79313161 GenBank AGX54704.1 581 Sequence 9764 from patent US 8541208
GI:15231929 GenBank AGX64144.1 581 Sequence 28398 from patent US 8541208
GI:79313161 GenBank AGX64144.1 581 Sequence 28398 from patent US 8541208

Related Sequences to LMP010846 proteins

Reference Database Accession Length Protein Name
GI:238479688 EMBL CBU87769.1 581 unnamed protein product [Arabidopsis thaliana]
GI:238479688 EMBL CBU96716.1 581 unnamed protein product [Arabidopsis thaliana]
GI:238479688 GenBank AAG50827.1 581 phosphoinositide specific phospholipase (AtPLC2) [Arabidopsis thaliana]
GI:238479688 GenBank AEE74641.1 581 phosphoinositide phospholipase C 2 [Arabidopsis thaliana]
GI:15231929 GenBank EOA30191.1 584 hypothetical protein CARUB_v10013310mg [Capsella rubella]
GI:79313161 GenBank EOA30191.1 584 hypothetical protein CARUB_v10013310mg [Capsella rubella]
GI:15231929 GenBank KFK38259.1 581 phosphoinositide phospholipase c 2 [Arabis alpina]
GI:79313161 GenBank KFK38259.1 581 phosphoinositide phospholipase c 2 [Arabis alpina]
GI:238479688 RefSeq NP_001030660.1 581 phosphoinositide phospholipase C 2 [Arabidopsis thaliana]
GI:15231929 RefSeq XP_006297293.1 584 hypothetical protein CARUB_v10013310mg [Capsella rubella]
GI:79313161 RefSeq XP_006297293.1 584 hypothetical protein CARUB_v10013310mg [Capsella rubella]
GI:79313161 RefSeq XP_010461812.1 584 PREDICTED: phosphoinositide phospholipase C 2 [Camelina sativa]
GI:15231929 RefSeq XP_010461812.1 584 PREDICTED: phosphoinositide phospholipase C 2 [Camelina sativa]
GI:15231929 RefSeq XP_010464460.1 586 PREDICTED: phosphoinositide phospholipase C 2-like [Camelina sativa]
GI:79313161 RefSeq XP_010464460.1 586 PREDICTED: phosphoinositide phospholipase C 2-like [Camelina sativa]
GI:79313161 RefSeq XP_010486390.1 585 PREDICTED: phosphoinositide phospholipase C 2-like isoform X1 [Camelina sativa]
GI:15231929 RefSeq XP_010486390.1 585 PREDICTED: phosphoinositide phospholipase C 2-like isoform X1 [Camelina sativa]
GI:238479688 SwissProt Q39033.1 581 RecName: Full=Phosphoinositide phospholipase C 2; AltName: Full=Phosphoinositide phospholipase PLC2; Short=AtPLC2; Short=PI-PLC2 [Arabidopsis thaliana]