Gene/Proteome Database (LMPD)

LMPD ID
LMP010851
Gene ID
824760
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phosphoinositide phospholipase C 7
Gene Symbol
AT3G55940
Alternate Names
phosphoinositide phospholipase C 7
Chromosome
3
EC Number
3.1.4.11

Proteins

phosphoinositide phospholipase C 7
Refseq ID NP_191153
Protein GI 15228780
UniProt ID Q9LY51
mRNA ID NM_115452
Length 584
RefSeq Status REVIEWED
MSKQTYKVCFCFRRRYRHTVSVAPAEIKTLFDNYSDKGLMTTDLLLRFLIDVQKQDKATKEEAQDIVNASSSLLHRNGLHLDAFFKYLFAVTNSPLSSLEVHQDMDAPLSHYFIYTGHNSYLTGNQLSSDCSELPIIEALKKGVRVIELDIWPNSDEDGIDVLHGRTLTSPVELIKCLRAIREHAFDVSDYPVVVTLEDHLTPKLQAKVAEMVTDIFGEMLFTPPSGECLKEFPSPAFLKKRIMISTKPPKEYKAATDDDLVKKGRDLGDKEVWGREVPSFIRRDRSVDKNDSNGDDDDDDDDDDDDDDGDDKIKKNAPPEYKHLIAIEAGKPKGGITECLKVDPDKVRRLSLSEEQLEKASEKYAKQIVRFTQRNLLRVYPKGTRITSSNYNPLIAWSHGAQMVAFNMQGLGRSLWVMQGMFRGNGGCGYIKKPDLLLKSNAVFDPEATLPVKTTLRVTIYMGEGWYYDFPHTHFDRYSPPDFYTRVGIAGVPADTVMKKTKTLEDNWIPAWDEVFEFPLTVPELALLRIEVHEYDMSEKDDFGGQICLPVWELRQGIRAVPLRNQDGVKCRSVKLLVRLEFV

Gene Information

Entrez Gene ID
824760
Gene Name
phosphoinositide phospholipase C 7
Gene Symbol
AT3G55940
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005886 IDA:TAIR C plasma membrane
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00562 Inositol phosphate metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
6254346 Signaling by FGFR1 fusion mutants

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR011992 EF-hand domain pair
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like

UniProt Annotations

Entry Information

Gene Name
phosphoinositide phospholipase C 7
Protein Entry
PLCD7_ARATH
UniProt ID
Q9LY51
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9LY51-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=2; IsoId=Q9LY51-2; Sequence=VSP_032149, VSP_032150; Note=No experimental confirmation available. Potentially inactive.;
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Cofactor Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. {ECO:0000250}.
Similarity Contains 1 C2 domain. {ECO:0000255|PROSITE- ProRule:PRU00041}.
Similarity Contains 1 EF-hand-like domain. {ECO:0000305}.
Similarity Contains 1 PI-PLC X-box domain. {ECO:0000255|PROSITE- ProRule:PRU00270}.
Similarity Contains 1 PI-PLC Y-box domain. {ECO:0000255|PROSITE- ProRule:PRU00271}.
Subcellular Location Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity Expressed in leaves, roots, flowers and siliques. {ECO:0000269|Ref.3}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010851 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15228780 RefSeq NP_191153 584 phosphoinositide phospholipase C 7

Identical Sequences to LMP010851 proteins

Reference Database Accession Length Protein Name
GI:15228780 EMBL CBF62905.1 584 unnamed protein product [Arabidopsis thaliana]
GI:15228780 EMBL CBU87781.1 584 unnamed protein product [Arabidopsis thaliana]
GI:15228780 EMBL CBU96728.1 584 unnamed protein product [Arabidopsis thaliana]
GI:15228780 GenBank AEE79459.1 584 phosphoinositide phospholipase C 7 [Arabidopsis thaliana]
GI:15228780 GenBank AGX54716.1 584 Sequence 9788 from patent US 8541208
GI:15228780 GenBank AGX64156.1 584 Sequence 28422 from patent US 8541208

Related Sequences to LMP010851 proteins

Reference Database Accession Length Protein Name
GI:15228780 GenBank EFH52602.1 585 hypothetical protein ARALYDRAFT_486035 [Arabidopsis lyrata subsp. lyrata]
GI:15228780 GenBank EOA23711.1 584 hypothetical protein CARUB_v10016918mg [Capsella rubella]
GI:15228780 RefSeq XP_002876343.1 585 hypothetical protein ARALYDRAFT_486035 [Arabidopsis lyrata subsp. lyrata]
GI:15228780 RefSeq XP_006290813.1 584 hypothetical protein CARUB_v10016918mg [Capsella rubella]
GI:15228780 RefSeq XP_010516186.1 581 PREDICTED: phosphoinositide phospholipase C 7-like isoform X2 [Camelina sativa]
GI:15228780 RefSeq XP_010427395.1 584 PREDICTED: phosphoinositide phospholipase C 7 [Camelina sativa]