Gene/Proteome Database (LMPD)

LMPD ID
LMP010865
Gene ID
827587
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phospholipase A1-IIgamma
Gene Symbol
AT4G18550
Synonyms
F28J12.210; F28J12_210
Alternate Names
phospholipase A1-IIgamma
Chromosome
4
EC Number
3.1.1.-

Proteins

phospholipase A1-IIgamma
Refseq ID NP_193590
Protein GI 15233922
UniProt ID O49523
mRNA ID NM_117969
Length 419
RefSeq Status REVIEWED
MKRKKKEEEEEKLIVTREFAKRWRDLSGQNHWKGMLQPLDQDLREYIIHYGEMAQAGYDTFNINTESQFAGASIYSRKDFFAKVGLEIAHPYTKYKVTKFIYATSDIHVPESFLLFPISREGWSKESNWMGYVAVTDDQGTALLGRRDIVVSWRGSVQPLEWVEDFEFGLVNAIKIFGERNDQVQIHQGWYSIYMSQDERSPFTKTNARDQVLREVGRLLEKYKDEEVSITICGHSLGAALATLSATDIVANGYNRPKSRPDKSCPVTAFVFASPRVGDSDFRKLFSGLEDIRVLRTRNLPDVIPIYPPIGYSEVGDEFPIDTRKSPYMKSPGNLATFHCLEGYLHGVAGTQGTNKADLFRLDVERAIGLVNKSVDGLKDECMVPGKWRVLKNKGMAQQDDGSWELVDHEIDDNEDLDF

Gene Information

Entrez Gene ID
827587
Gene Name
phospholipase A1-IIgamma
Gene Symbol
AT4G18550
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IDA:UniProtKB C cytoplasm
GO:0047372 IDA:TAIR F acylglycerol lipase activity
GO:0008970 IDA:UniProtKB F phosphatidylcholine 1-acylhydrolase activity
GO:0046340 IDA:TAIR P diacylglycerol catabolic process
GO:0019915 IMP:TAIR P lipid storage
GO:0052651 IDA:TAIR P monoacylglycerol catabolic process
GO:0010187 IMP:UniProtKB P negative regulation of seed germination

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6803 phosphatidylcholine acyl editing
LIPASYN-PWY phospholipases
LIPASYN-PWY phospholipases
LIPAS-PWY triacylglycerol degradation

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR002921 Fungal lipase-like domain

UniProt Annotations

Entry Information

Gene Name
phospholipase A1-IIgamma
Protein Entry
DSEL_ARATH
UniProt ID
O49523
Species
Arabidopsis

Comments

Comment Type Description
Biophysicochemical Properties pH dependence: Optimum pH is 5-6 with 1,3-DAG as substrate and at 30 degrees Celsius. {ECO:0000269|PubMed:21477884};
Disruption Phenotype Mildly fast-growing seedlings regardless of the presence of an exogenous carbon source, accompanied by a better beta-oxidation and mobilization of seed storage oils. {ECO:0000269|PubMed:21477884}.
Function Acylhydrolase that catalyzes the hydrolysis of 1,3- diacylglycerol (1,3-DAG) and 1-monoacylglycerol (1-MAG) at the sn- 1 position. High activity toward 1,3-DAG and 1-MAG, but low activity toward 1,2-diacylglycerol (1,2-DAG) and 1- lysophosphatidylcholine (1-LPC), and no activity toward phosphatidylcholine (PC), monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG), triacylglycerol (TAG) and 2- monoacylglycerol (2-MAG). May be involved in the negative regulation of seedling establishment by inhibiting the breakdown, beta-oxidation and mobilization of seed storage oils. {ECO:0000269|PubMed:21477884}.
Sequence Caution Sequence=BAC42692.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Similarity Belongs to the AB hydrolase superfamily. Lipase family. {ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21477884}.
Tissue Specificity Expressed in seedlings, stems and siliques, and, to a lower extent, in flowers. {ECO:0000269|PubMed:21477884}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010865 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15233922 RefSeq NP_193590 419 phospholipase A1-IIgamma

Identical Sequences to LMP010865 proteins

Reference Database Accession Length Protein Name
GI:15233922 EMBL CAB78857.1 419 lipase-like protein [Arabidopsis thaliana]
GI:15233922 GenBank ABN04794.1 419 At4g18550 [Arabidopsis thaliana]
GI:15233922 GenBank ACW96919.1 419 Sequence 17007 from patent US 7569389
GI:15233922 GenBank ACW97979.1 419 Sequence 18450 from patent US 7569389
GI:15233922 GenBank AEE84060.1 419 alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]
GI:15233922 SwissProt O49523.1 419 RecName: Full=Phospholipase A1-IIgamma; AltName: Full=DAD1-like seedling establishment-related lipase; Short=AtDSEL; Short=Phospholipase DSEL [Arabidopsis thaliana]

Related Sequences to LMP010865 proteins

Reference Database Accession Length Protein Name
GI:15233922 GenBank AAW01404.1 418 Sequence 12 from patent US 6774284
GI:15233922 GenBank ACW97977.1 436 Sequence 18448 from patent US 7569389
GI:15233922 GenBank ACW97978.1 428 Sequence 18449 from patent US 7569389
GI:15233922 RefSeq XP_010434519.1 435 PREDICTED: phospholipase A1-IIgamma-like isoform X2 [Camelina sativa]
GI:15233922 RefSeq XP_010439839.1 435 PREDICTED: phospholipase A1-IIgamma-like [Camelina sativa]
GI:15233922 RefSeq XP_010496242.1 435 PREDICTED: phospholipase A1-IIgamma [Camelina sativa]