Gene/Proteome Database (LMPD)

LMPD ID
LMP010944
Gene ID
843840
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
lysophosphatidyl acyltransferase 4
Gene Symbol
LPAT4
Synonyms
F25A4.2; F25A4_2; LPAT4; lysophosphatidyl acyltransferase 4
Alternate Names
lysophosphatidyl acyltransferase 4
Chromosome
1
EC Number
2.3.1.51

Proteins

lysophosphatidyl acyltransferase 4
Refseq ID NP_565098
Protein GI 18410753
UniProt ID Q8L4Y2
mRNA ID NM_106159
Length 378
RefSeq Status REVIEWED
MEVCGDLKSDNLKNRPLTPLRILRGLMILLVFLSTAFMFLLYFAPIAALGLRLLSVQQSRKVVSLIFGLWLALWPYLFETVNGTTVVFSGDIIPVEKRVLLIANHRTEVDWMYLWNIALRKGCLGYIKYVLKSSLMKLPIFGWGFHVLEFIPVERKREVDEPVLLQMLSSFKDPQEPLWLALFPEGTDFTEEKCKRSQKFAAEVGLPALSNVLLPKTRGFGVCLEVLHNSLDAVYDLTIAYKPRCPSFMDNVFGTDPSEVHIHVRRVLLKEIPANEAESSAWLMDSFKLKDKLLSDFNAQGKFPNQRPEEELSVLKCIATFAGVISLTVVFIYLTLYSHSCFKVYACLSGTYLTFATYYKFQPSPGCFREDSCKVKNH
lysophosphatidyl acyltransferase 4
Refseq ID NP_974144
Protein GI 42572107
UniProt ID Q8L4Y2
mRNA ID NM_202415
Length 378
RefSeq Status REVIEWED
Protein sequence is identical to GI:18410753 (mRNA isoform)

Gene Information

Entrez Gene ID
843840
Gene Name
lysophosphatidyl acyltransferase 4
Gene Symbol
LPAT4
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0003841 IEA:UniProtKB-EC F 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0016024 IEA:UniProtKB-UniPathway P CDP-diacylglycerol biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00561 Glycerolipid metabolism
ath00564 Glycerophospholipid metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
6254313 Acyl chain remodeling of CL
6253800 Synthesis of PA

Domain Information

InterPro Annotations

Accession Description
IPR002123 Phospholipid/glycerol acyltransferase

UniProt Annotations

Entry Information

Gene Name
lysophosphatidyl acyltransferase 4
Protein Entry
LPAT4_ARATH
UniProt ID
Q8L4Y2
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.
Domain The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}.
Function May convert lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position (By similarity). Has no activity when expressed in bacteria or yeast. {ECO:0000250}.
Pathway Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.
Sequence Caution Sequence=AAD55275.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAG51931.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Widely expressed at low level. {ECO:0000269|PubMed:15772283}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010944 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18410753 RefSeq NP_565098 378 lysophosphatidyl acyltransferase 4

Identical Sequences to LMP010944 proteins

Reference Database Accession Length Protein Name
GI:18410753 GenBank AAM61283.1 378 putative acyl-CoA:1-acylglycerol-3-phosphate acyltransferase [Arabidopsis thaliana]
GI:18410753 GenBank AAN65123.1 378 putative acyl-CoA:1-acylglycerol-3-phosphate acyltransferase [Arabidopsis thaliana]
GI:18410753 GenBank AEE35662.1 378 lysophosphatidyl acyltransferase 4 [Arabidopsis thaliana]
GI:18410753 GenBank AEE35663.1 378 lysophosphatidyl acyltransferase 4 [Arabidopsis thaliana]
GI:18410753 RefSeq NP_974144.1 378 lysophosphatidyl acyltransferase 4 [Arabidopsis thaliana]
GI:18410753 SwissProt Q8L4Y2.1 378 RecName: Full=Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4; AltName: Full=Lysophosphatidyl acyltransferase 4 [Arabidopsis thaliana]

Related Sequences to LMP010944 proteins

Reference Database Accession Length Protein Name
GI:18410753 GenBank EFH63828.1 379 hypothetical protein ARALYDRAFT_476640 [Arabidopsis lyrata subsp. lyrata]
GI:18410753 GenBank EOA33409.1 378 hypothetical protein CARUB_v10020475mg [Capsella rubella]
GI:18410753 RefSeq XP_002887569.1 379 hypothetical protein ARALYDRAFT_476640 [Arabidopsis lyrata subsp. lyrata]
GI:18410753 RefSeq XP_006300511.1 378 hypothetical protein CARUB_v10020475mg [Capsella rubella]
GI:18410753 RefSeq XP_010416360.1 379 PREDICTED: probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4 [Camelina sativa]
GI:18410753 RefSeq XP_010416361.1 379 PREDICTED: probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4 [Camelina sativa]