Gene/Proteome Database (LMPD)

LMPD ID
LMP010950
Gene ID
829075
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Gene Symbol
AT4G29540
Synonyms
T16L4.50; T16L4_50
Alternate Names
probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Chromosome
4
EC Number
2.3.1.129

Proteins

probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Refseq ID NP_194683
Protein GI 30688366
UniProt ID Q9SU91
mRNA ID NM_119099
Length 334
RefSeq Status REVIEWED
MISLLKAREKLLSPLVSSTIRRLSSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFMSTETVSLSFEERLTELDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWLDSTT
probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Refseq ID NP_001031749
Protein GI 79325527
UniProt ID Q9SU91
mRNA ID NM_001036672
Length 336
RefSeq Status REVIEWED
MISLLKAREKLLSPLVSSTIRRLSSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWLDSTT

Gene Information

Entrez Gene ID
829075
Gene Name
probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Gene Symbol
AT4G29540
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:TAIR C mitochondrion
GO:0008780 IDA:TAIR F acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
GO:0009245 IEA:UniProtKB-KW P lipid A biosynthetic process
GO:2001289 IMP:TAIR P lipid X metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
NAGLIPASYN-PWY lipid IVA biosynthesis
KDO-NAGLIPASYN-PWY superpathway of (KDO)2-lipid A biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR001451 Bacterial transferase hexapeptide repeat
IPR011004 Trimeric LpxA-like
IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal

UniProt Annotations

Entry Information

Gene Name
probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Protein Entry
LPXA_ARATH
UniProt ID
Q9SU91
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9SU91-1; Sequence=Displayed; Name=2; IsoId=Q9SU91-2; Sequence=VSP_045743; Note=No experimental confirmation available.;
Catalytic Activity (R)-3-hydroxytetradecanoyl-[acyl-carrier- protein] + UDP-N-acetyl-alpha-D-glucosamine = [acyl-carrier- protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetyl-alpha-D- glucosamine. {ECO:0000269|PubMed:22545860}.
Disruption Phenotype No visible phenotype under normal growth conditions, but plants lacking LPXA accumulate very low levels of 2,3-diacylglucosamine-1-phosphate. {ECO:0000269|PubMed:21709257}.
Function Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential). {ECO:0000305}.
Pathway Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. {ECO:0000269|PubMed:21709257}.
Similarity Belongs to the transferase hexapeptide repeat family. LpxA subfamily. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:21709257}.
Subunit Homotrimer. {ECO:0000269|PubMed:22545860}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010950 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
79325527 RefSeq NP_001031749 336 probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
30688366 RefSeq NP_194683 334 probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

Identical Sequences to LMP010950 proteins

Reference Database Accession Length Protein Name
GI:79325527 DBBJ BAD43226.1 336 UDP-N-acetylglucosamine O-acyltransferase - like protein [Arabidopsis thaliana]
GI:79325527 EMBL CAB45314.1 336 UDP-N-acetylglucosamine O-acyltransferase-like protein [Arabidopsis thaliana]
GI:79325527 EMBL CAB79712.1 336 UDP-N-acetylglucosamine O-acyltransferase-like protein [Arabidopsis thaliana]
GI:30688366 GenBank AAN13071.1 334 putative UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis thaliana]
GI:30688366 GenBank AEE85641.1 334 probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis thaliana]
GI:79325527 GenBank AEE85642.1 336 probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis thaliana]
GI:79325527 SwissProt Q9SU91.1 336 RecName: Full=Probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, mitochondrial; Short=UDP-N-acetylglucosamine acyltransferase; AltName: Full=Protein LIPID X A; Short=AtLpxA; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP010950 proteins

Reference Database Accession Length Protein Name
GI:30688366 DBBJ BAD43226.1 336 UDP-N-acetylglucosamine O-acyltransferase - like protein [Arabidopsis thaliana]
GI:30688366 EMBL CAB45314.1 336 UDP-N-acetylglucosamine O-acyltransferase-like protein [Arabidopsis thaliana]
GI:30688366 EMBL CAB79712.1 336 UDP-N-acetylglucosamine O-acyltransferase-like protein [Arabidopsis thaliana]
GI:79325527 GenBank AAN13071.1 334 putative UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis thaliana]
GI:79325527 GenBank EFH45686.1 336 acyl--UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis lyrata subsp. lyrata]
GI:79325527 GenBank AEE85641.1 334 probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis thaliana]
GI:30688366 GenBank AEE85642.1 336 probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis thaliana]
GI:79325527 GenBank EOA15562.1 334 hypothetical protein CARUB_v10005206mg [Capsella rubella]
GI:79325527 RefSeq NP_194683.2 334 probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis thaliana]
GI:30688366 RefSeq NP_001031749.1 336 probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis thaliana]
GI:79325527 RefSeq XP_002869427.1 336 acyl--UDP-N-acetylglucosamine O-acyltransferase [Arabidopsis lyrata subsp. lyrata]
GI:30688366 SwissProt Q9SU91.1 336 RecName: Full=Probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, mitochondrial; Short=UDP-N-acetylglucosamine acyltransferase; AltName: Full=Protein LIPID X A; Short=AtLpxA; Flags: Precursor [Arabidopsis thaliana]