Gene/Proteome Database (LMPD)

LMPD ID
LMP010952
Gene ID
842901
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
acyl activating enzyme 12
Gene Symbol
AAE12
Synonyms
acyl activating enzyme 12; F12P19.6; F12P19_6
Alternate Names
acyl activating enzyme 12
Chromosome
1
EC Number
6.2.1.-

Proteins

acyl activating enzyme 12
Refseq ID NP_176764
Protein GI 15218840
UniProt ID Q9SS00
mRNA ID NM_105261
Length 578
RefSeq Status REVIEWED
MDNLALCEANNVPLTPITFLKRASECYPNRTSIIYGKTRFTWPQTYDRCCRLAASLISLNIGKNDVVSVVAPNTPAMYEMHFAVPMAGAVLNPINTRLDATSIAAILRHAKPKILFIYRSFEPLAREILQLLSSEDSNLNLPVIFIHEIDFPKRVSSEESDYECLIQRGEPTPLLLARMFCIQDEHDPISLNYTSGTTADPKGVVISHRGAYLSTLSAIIGWEMGTCPVYLWTLPMFHCNGWTFTWGTAARGGTSVCMRHVTAPEIYKNIEMHNVTHMCCVPTVFNILLKGNSLDLSHRSGPVHVLTGGSPPPAALVKKVQRLGFQVMHAYGLTEATGPVLFCEWQDEWNRLPENQQMELKARQGLSILGLTEVDVRNKETQESVPRDGKTMGEIVMKGSSIMKGYLKNPKATYEAFKHGWLNSGDVGVIHPDGHVEIKDRSKDIIISGGENISSVEVENIIYKYPKVLETAVVAMPHPTWGETPCAFVVLEKGETNNEDREDKLVTKERDLIEYCRENLPHFMCPRKVVFLDELPKNGNGKILKPKLRDIAKGLVAEDEVNVRSKVQRPVEHFTSRL

Gene Information

Entrez Gene ID
842901
Gene Name
acyl activating enzyme 12
Gene Symbol
AAE12
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005777 IEA:UniProtKB-KW C peroxisome
GO:0016874 IEA:UniProtKB-KW F ligase activity
GO:0006631 IEA:UniProtKB-KW P fatty acid metabolic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6443 benzoate biosynthesis I (CoA-dependent, beta-oxidative)
PWY-283 benzoate degradation II (aerobic and anaerobic)

Domain Information

InterPro Annotations

Accession Description
IPR025110 AMP-binding enzyme C-terminal domain
IPR000873 AMP-dependent synthetase/ligase

UniProt Annotations

Entry Information

Gene Name
acyl activating enzyme 12
Protein Entry
AAE12_ARATH
UniProt ID
Q9SS00
Species
Arabidopsis

Comments

Comment Type Description
Function May act as an acid--thiol ligase that activates carboxylic acids by forming acyl-CoAs. {ECO:0000250}.
Similarity Belongs to the ATP-dependent AMP-binding enzyme family. {ECO:0000305}.
Subcellular Location Peroxisome {ECO:0000305}.
Tissue Specificity Expressed at low levels in leaves. {ECO:0000269|PubMed:12805634}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010952 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15218840 RefSeq NP_176764 578 acyl activating enzyme 12

Identical Sequences to LMP010952 proteins

Reference Database Accession Length Protein Name
GI:15218840 EMBL CBD30337.1 578 unnamed protein product [Arabidopsis thaliana]
GI:15218840 GenBank AAF06050.1 578 Similar to gb|X94625 amp-binding protein from Brassica napus and is a member of the PF|00501 AMP-binding enzymes [Arabidopsis thaliana]
GI:15218840 GenBank ACX18934.1 578 Sequence 46937 from patent US 7569389
GI:15218840 GenBank AEE34437.1 578 acyl activating enzyme 12 [Arabidopsis thaliana]
GI:15218840 SwissProt Q9SS00.1 578 RecName: Full=Probable acyl-activating enzyme 12, peroxisomal [Arabidopsis thaliana]

Related Sequences to LMP010952 proteins

Reference Database Accession Length Protein Name
GI:15218840 EMBL CBD30336.1 580 unnamed protein product [Arabidopsis thaliana]
GI:15218840 GenBank AAK91428.1 578 At1g65890/F12P19_6 [Arabidopsis thaliana]
GI:15218840 GenBank AAL31150.1 578 At1g65890/F12P19_6 [Arabidopsis thaliana]
GI:15218840 GenBank AAP03023.1 578 acyl-activating enzyme 12 [Arabidopsis thaliana]
GI:15218840 GenBank ACX18933.1 594 Sequence 46936 from patent US 7569389
GI:15218840 SwissProt Q9SS01.1 580 RecName: Full=Benzoate--CoA ligase, peroxisomal; AltName: Full=Acyl-activating enzyme 20; AltName: Full=Protein BENZOYLOXYGLUCOSINOLATE 1 [Arabidopsis thaliana]