Gene/Proteome Database (LMPD)

LMPD ID
LMP010970
Gene ID
843500
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
choline kinase 1
Gene Symbol
CK1
Synonyms
ATCK1; CHOLINE KINASE; choline kinase 1; CK; CK1; F14O23.8; F14O23_8
Alternate Names
choline kinase 1
Chromosome
1
EC Number
2.7.1.32
Summary
Encodes choline kinase. mRNA levels are increased in response to wounding.
Orthologs
View orthologs and multiple alignments for CK1

Proteins

choline kinase 1
Refseq ID NP_177315
Protein GI 15217543
UniProt ID Q9M9H6
mRNA ID NM_105828
Length 346
RefSeq Status REVIEWED
MAIKTKTSLIPSCSSPEDLKRVLQTLGSSWGDVVEDLERLEVVPLKGAMTNEVYQINWPTLNGEDVHRKVLVRIYGDGVDLFFNRGDEIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTLSADDLRVAETSDFIAAKLREFHKLDMPGPKNVLLWERLRTWLKEAKNLASPIEMDKYRLEGLENEINLLEERLTRDDQEIGFCHNDLQYGNVMIDEVTNAITIIDYEYSSFNPIAYDIANHFCEMAANYHSDTPHVLDYTLYPGEGERRRFISTYLGSTGNATSDKEVERLLKDAESYTLANHIFWGLWGIISGHVNKIEFDYMEYARQRFEQYWLRKPLLLEG

Gene Information

Entrez Gene ID
843500
Gene Name
choline kinase 1
Gene Symbol
CK1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004103 ISS:TAIR F choline kinase activity
GO:0006657 ISS:GOC P CDP-choline pathway
GO:0009611 IEP:TAIR P response to wounding

KEGG Pathway Links

KEGG Pathway ID Description
ath00564 Glycerophospholipid metabolism
ath_M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE

REACTOME Pathway Links

REACTOME Pathway ID Description
6254221 Synthesis of PC
6254314 Synthesis of PE

Domain Information

InterPro Annotations

Accession Description
IPR026712 Choline/Ethanolamine kinase
IPR007521 Choline kinase, N-terminal
IPR011009 Protein kinase-like domain

UniProt Annotations

Entry Information

Gene Name
choline kinase 1
Protein Entry
CK1_ARATH
UniProt ID
Q9M9H6
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + choline = ADP + phosphocholine.
Function Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylcholine biosynthesis (By similarity). {ECO:0000250}.
Induction By wounding, and salt and osmotic stresses. {ECO:0000269|PubMed:15147879, ECO:0000269|PubMed:9342878}.
Pathway Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphocholine from choline: step 1/1.
Sequence Caution Sequence=AAG51828.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the choline/ethanolamine kinase family. {ECO:0000305}.
Tissue Specificity Expressed in roots. Expressed at low levels in cauline leaves and flowers. {ECO:0000269|PubMed:9342878}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010970 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15217543 RefSeq NP_177315 346 choline kinase 1

Identical Sequences to LMP010970 proteins

Reference Database Accession Length Protein Name
GI:15217543 DBBJ BAF01619.1 346 choline kinase like protein [Arabidopsis thaliana]
GI:15217543 DBBJ BAF02205.1 346 choline kinase like protein [Arabidopsis thaliana]
GI:15217543 EMBL CAW88557.1 346 unnamed protein product [Arabidopsis thaliana]
GI:15217543 EMBL CBC91140.1 346 unnamed protein product [Arabidopsis thaliana]
GI:15217543 EMBL CBD32536.1 346 unnamed protein product [Arabidopsis thaliana]
GI:15217543 GenBank AEE35220.1 346 choline kinase 1 [Arabidopsis thaliana]

Related Sequences to LMP010970 proteins

Reference Database Accession Length Protein Name
GI:15217543 GenBank AAG51828.1 330 putative choline kinase; 4535-2895 [Arabidopsis thaliana]
GI:15217543 GenBank EFH63642.1 347 hypothetical protein ARALYDRAFT_895010 [Arabidopsis lyrata subsp. lyrata]
GI:15217543 GenBank EOA34450.1 348 hypothetical protein CARUB_v10021986mg [Capsella rubella]
GI:15217543 GenBank ESQ28039.1 348 hypothetical protein EUTSA_v10018799mg [Eutrema salsugineum]
GI:15217543 RefSeq XP_002887383.1 347 hypothetical protein ARALYDRAFT_895010 [Arabidopsis lyrata subsp. lyrata]
GI:15217543 RefSeq XP_006301552.1 348 hypothetical protein CARUB_v10021986mg [Capsella rubella]