Gene/Proteome Database (LMPD)

LMPD ID
LMP010971
Gene ID
843772
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
choline kinase
Gene Symbol
AT1G74320
Synonyms
F1O17.1; F1O17_1
Alternate Names
choline kinase
Chromosome
1
EC Number
2.7.1.32
Summary
encodes a choline kinase, whose expression is induced by high salt and mannitol.
Orthologs
View orthologs and multiple alignments for AT1G74320

Proteins

choline kinase
Refseq ID NP_177572
Protein GI 22330627
UniProt ID Q8L518
mRNA ID NM_106092
Length 350
RefSeq Status REVIEWED
MTMGGTEKNVENKQYRLPREVKEALQAIASEWEDVIDSKALQVIPLKGAMTNEVFQIKWPTREKGPSRKVLVRIYGEGVEIFFDREDEIRTFEFMSKHGHGPLLLGRFGNGRIEEFLHARTLSACDLRDPEISGRIATRMKEFHGLEMPGAKKALLWDRLRNWLTACKRLASPEEAKSFRLDVMEMEINMLEKSLFDNDENIGFCHNDLQYGNIMMDEETKAITIIDYEYSCYNPVAYDIANHFCEMAADYHTETPHIMDYSKYPGVEERQRFLKTYMSYSDEKPSDTMVKKLLEDVEKYTLASHLIWGLWGIISEHVNEIDFDYMEYARQRFEQYWLTKPRLLAASEHK

Gene Information

Entrez Gene ID
843772
Gene Name
choline kinase
Gene Symbol
AT1G74320
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004103 IEA:UniProtKB-EC F choline kinase activity

KEGG Pathway Links

KEGG Pathway ID Description
ath00564 Glycerophospholipid metabolism
ath_M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE

REACTOME Pathway Links

REACTOME Pathway ID Description
6254221 Synthesis of PC
6254314 Synthesis of PE

Domain Information

InterPro Annotations

Accession Description
IPR026712 Choline/Ethanolamine kinase
IPR011009 Protein kinase-like domain

UniProt Annotations

Entry Information

Gene Name
choline kinase
Protein Entry
CK2_ARATH
UniProt ID
Q8L518
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + choline = ADP + phosphocholine.
Function Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylcholine biosynthesis (By similarity). {ECO:0000250}.
Induction By wounding, and salt and osmotic stresses. {ECO:0000269|PubMed:15147879}.
Pathway Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphocholine from choline: step 1/1.
Sequence Caution Sequence=AAG52400.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Similarity Belongs to the choline/ethanolamine kinase family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010971 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
22330627 RefSeq NP_177572 350 choline kinase

Identical Sequences to LMP010971 proteins

Reference Database Accession Length Protein Name
GI:22330627 EMBL CAW88575.1 350 unnamed protein product [Arabidopsis thaliana]
GI:22330627 EMBL CBC91156.1 350 unnamed protein product [Arabidopsis thaliana]
GI:22330627 GenBank AAM98234.1 350 putative choline kinase [Arabidopsis thaliana]
GI:22330627 GenBank AAP42750.1 350 At1g74320 [Arabidopsis thaliana]
GI:22330627 GenBank AEE35577.1 350 protein kinase domain-containing protein [Arabidopsis thaliana]
GI:22330627 SwissProt Q8L518.1 350 RecName: Full=Probable choline kinase 2 [Arabidopsis thaliana]

Related Sequences to LMP010971 proteins

Reference Database Accession Length Protein Name
GI:22330627 EMBL CAW88590.1 348 unnamed protein product [Arabidopsis thaliana]
GI:22330627 EMBL CBC91170.1 348 unnamed protein product [Arabidopsis thaliana]
GI:22330627 GenBank AAG52400.1 348 putative choline kinase; 11757-10052 [Arabidopsis thaliana]
GI:22330627 GenBank EFH63795.1 348 hypothetical protein ARALYDRAFT_895300 [Arabidopsis lyrata subsp. lyrata]
GI:22330627 GenBank EOA35372.1 350 hypothetical protein CARUB_v10020564mg [Capsella rubella]
GI:22330627 RefSeq XP_002887536.1 348 hypothetical protein ARALYDRAFT_895300 [Arabidopsis lyrata subsp. lyrata]