Gene/Proteome Database (LMPD)

LMPD ID
LMP010978
Gene ID
823579
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
fatty acyl-CoA reductase 4
Gene Symbol
FAR4
Synonyms
fatty acid reductase 4
Alternate Names
fatty acyl-CoA reductase 4
Chromosome
3
EC Number
1.2.1.n2
Summary
Encodes a member of the eight-member gene family encoding alcohol-forming fatty acyl-CoA reductases (FARs) identified in Arabidopsis thaliana. Three of the FARs, FAR1 (At5g22500), FAR4 (At3g44540) and FAR5 (At3g44550), are shown to generate the fatty alcohols found in root, seed coat, and wound-induced leaf tissue.
Orthologs
View orthologs and multiple alignments for FAR4

Proteins

fatty acyl-CoA reductase 4
Refseq ID NP_190040
Protein GI 79432534
UniProt ID Q9LXN3
mRNA ID NM_114322
Length 493
RefSeq Status REVIEWED
MDSNCIQFLHDKTILVTGVPGFLAKVFVEKILRIQPKVKKLFLLLRAADNESAMQRFHSEVLEKDLFRVLKNALGDENLKAFITEKVVPIPGDISVDNLGVKGSDLLQHMWNEIDIIVNVAATTNFDERYDVGLSVNTFGPLNVLNFAKKCVKGQLLLHVSTAYVRGEKSGLLHEKTFHMGETLNGHRKLVIETEMELMKQKLKELQKQNCSEEEISQSMKDLGMSRAKLHGWPNTYVFTKSMGEMLLGNYRENLPIVIIRPTMITSTFSEPFPGWIEGLRTIDSVIVAYGKGRLKCFLADPNSVLDLIPVDMVANAMVTAAAIHAGKLGSQTVYHVGSSCKNPITFEQIHDLAASYFTKNPLVRRDGSSILVSKGTILSTMAQFSFYMTLRYKLPLQMLRLIYVIYPWWNGNKYKDIDRKIKLAMRLVDLYRPYVLFKGIFDDTNTEKLRLKRKEINKEMYGLFEFDPKSIDWEDYMTTIHIPGLITYVLKK
fatty acyl-CoA reductase 4
Refseq ID NP_001030809
Protein GI 79314181
UniProt ID Q9LXN3
mRNA ID NM_001035732
Length 433
RefSeq Status REVIEWED
MDSNCIQFLHDKTILVTGVPGFLAKVFVEKILRIQPKVKKLFLLLRAADNESAMQRFHSEVLEKDLFRVLKNALGDENLKAFITEKVVPIPGDISVDNLGVKGSDLLQHMWNEIDIIVNVAATTNFDERYDVGLSVNTFGPLNVLNFAKKCVKGQLLLHVSTAYVRGEKSGLLHEKTFHMGETLNGHRKLVIETEMELMKQKLKELQKQNCSEEEISQSMKDLGMSRAKLHGWPNTYVFTKSMGEMLLGNYRENLPIVIIRPTMITSTFSEPFPGWIEGLRTIDSVIVAYGKGRLKCFLADPNSVLDLIPVDMVANAMVTAAAIHAGKLGSQTVYHVGSSCKNPITFEQIHDLAASYFTKNPLVRRDGSSILVSKGTILSTMAQFSFYMTLRYKLPLQTLTARLSWRCGWSTSTDLMSCLRAYLTIRILRNCG

Gene Information

Entrez Gene ID
823579
Gene Name
fatty acyl-CoA reductase 4
Gene Symbol
FAR4
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0080019 IEA:InterPro F fatty-acyl-CoA reductase (alcohol-forming) activity
GO:0050062 IDA:TAIR F long-chain-fatty-acyl-CoA reductase activity
GO:0006629 IEA:UniProtKB-KW P lipid metabolic process
GO:0009651 IEP:TAIR P response to salt stress
GO:0009611 IMP:TAIR P response to wounding
GO:0010345 IMP:TAIR P suberin biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00073 Cutin, suberine and wax biosynthesis
ath04146 Peroxisome
ko04146 Peroxisome

REACTOME Pathway Links

REACTOME Pathway ID Description
6254165 Plasmalogen biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR026055 Fatty acyl-CoA reductase
IPR013120 Male sterility, NAD-binding
IPR016040 NAD(P)-binding domain

UniProt Annotations

Entry Information

Gene Name
fatty acyl-CoA reductase 4
Protein Entry
FACR4_ARATH
UniProt ID
Q9LXN3
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9LXN3-1; Sequence=Displayed; Note=Derived from EST data. No experimental confirmation available.; Name=2; IsoId=Q9LXN3-2; Sequence=VSP_037566, VSP_037567;
Catalytic Activity Hexadecanal + CoA + NADP(+) = hexadecanoyl-CoA + NADPH.
Function Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. {ECO:0000250}.
Similarity Belongs to the fatty acyl-CoA reductase family. {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010978 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
79432534 RefSeq NP_190040 493 fatty acyl-CoA reductase 4
79314181 RefSeq NP_001030809 433 fatty acyl-CoA reductase 4

Identical Sequences to LMP010978 proteins

Reference Database Accession Length Protein Name
GI:79314181 DBBJ BAE99400.1 433 acyl CoA reductase - protein [Arabidopsis thaliana]
GI:79432534 EMBL CAB88536.1 493 acyl CoA reductase-protein [Arabidopsis thaliana]
GI:79314181 GenBank ACF22894.1 433 At3g44540 [Arabidopsis thaliana]
GI:79432534 GenBank ACX17748.1 493 Sequence 45336 from patent US 7569389
GI:79432534 GenBank AEE77912.1 493 fatty acid reductase 4 [Arabidopsis thaliana]
GI:79314181 GenBank AEE77913.1 433 fatty acid reductase 4 [Arabidopsis thaliana]
GI:79432534 SwissProt Q9LXN3.1 493 RecName: Full=Probable fatty acyl-CoA reductase 4 [Arabidopsis thaliana]

Related Sequences to LMP010978 proteins

Reference Database Accession Length Protein Name
GI:79314181 EMBL CAB88536.1 493 acyl CoA reductase-protein [Arabidopsis thaliana]
GI:79314181 GenBank ACX17748.1 493 Sequence 45336 from patent US 7569389
GI:79432534 GenBank ACX21298.1 489 Sequence 50130 from patent US 7569389
GI:79432534 GenBank EFH51930.1 493 oxidoreductase, acting on the CH-CH group of donors [Arabidopsis lyrata subsp. lyrata]
GI:79314181 GenBank AEE77912.1 493 fatty acid reductase 4 [Arabidopsis thaliana]
GI:79432534 GenBank EOA12263.1 493 hypothetical protein CARUB_v10007993mg [Capsella rubella]
GI:79432534 GenBank EOA23870.1 493 hypothetical protein CARUB_v10017087mg [Capsella rubella]
GI:79314181 RefSeq NP_190040.3 493 fatty acyl-CoA reductase 4 [Arabidopsis thaliana]
GI:79432534 RefSeq XP_002875671.1 493 oxidoreductase, acting on the CH-CH group of donors [Arabidopsis lyrata subsp. lyrata]
GI:79432534 RefSeq XP_006290972.1 493 hypothetical protein CARUB_v10017087mg [Capsella rubella]
GI:79314181 RefSeq XP_010514784.1 433 PREDICTED: probable fatty acyl-CoA reductase 4 isoform X2 [Camelina sativa]
GI:79314181 SwissProt Q9LXN3.1 493 RecName: Full=Probable fatty acyl-CoA reductase 4 [Arabidopsis thaliana]