Gene/Proteome Database (LMPD)

LMPD ID
LMP011051
Gene ID
826811
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
probable sodium/metabolite cotransporter BASS5
Gene Symbol
BAT5
Synonyms
BASS5; BAT5; bile acid transporter 5; BILE ACID:SODIUM SYMPORTER FAMILY PROTEIN 5; F16J13.100; F16J13_100
Alternate Names
probable sodium/metabolite cotransporter BASS5
Chromosome
4
Summary
Required for the biosynthesis of methionine-derived glucosinolates. Involved in the transport of 2-keto acids between chloroplasts and the cytosol.
Orthologs
View orthologs and multiple alignments for BAT5

Proteins

probable sodium/metabolite cotransporter BASS5
Refseq ID NP_974538
Protein GI 42572883
UniProt ID F4JPW1
mRNA ID NM_202809
Length 407
RefSeq Status REVIEWED
MGVISPTETLFLKSQHRLLQPRNYSYALAFHSTRRVANFPRNSFSSLGSCSVDFPLRSNPISQNSKSIHPWRRYVSESDSNELYHKKVSSIMETLKQAYSFIPHGILLSTILALVYPPSFTWFKPRYFVPGLGFMMFAVGINSNERDFLEALKRPDAIFAGYIGQYLIKPLLGYIFGVIAVSLFNLPTSIGAGIMLVSCVSGAQLSNYTTFLTDPSLAALSIVMTSISTATAVLVTPMLSLLLIGKKLPVDVFGMISSILQVVITPIAAGLLLNRLFPRLSNAIKPFLPALTVIDMSCCIGAPLALNIDSILSPFGATILFLVITFHLLAFVAGYFFTGFFFSKAPDVKALQRTISYETGMQSSLLALALATKFFQDPLVGVPPAISTVVMSLMGVSLVTIWKNRKE
probable sodium/metabolite cotransporter BASS5
Refseq ID NP_567385
Protein GI 18413732
UniProt ID F4JPW1
mRNA ID NM_117273
Length 273
RefSeq Status REVIEWED
MMFAVGINSNERDFLEALKRPDAIFAGYIGQYLIKPLLGYIFGVIAVSLFNLPTSIGAGIMLVSCVSGAQLSNYTTFLTDPSLAALSIVMTSISTATAVLVTPMLSLLLIGKKLPVDVFGMISSILQVVITPIAAGLLLNRLFPRLSNAIKPFLPALTVIDMSCCIGAPLALNIDSILSPFGATILFLVITFHLLAFVAGYFFTGFFFSKAPDVKALQRTISYETGMQSSLLALALATKFFQDPLVGVPPAISTVVMSLMGVSLVTIWKNRKE

Gene Information

Entrez Gene ID
826811
Gene Name
probable sodium/metabolite cotransporter BASS5
Gene Symbol
BAT5
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009941 IMP:UniProtKB C chloroplast envelope
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0009536 IDA:TAIR C plastid
GO:0008508 IEA:InterPro F bile acid:sodium symporter activity
GO:0005215 IMP:TAIR F transporter activity
GO:0019761 IMP:TAIR P glucosinolate biosynthetic process
GO:0033506 IMP:UniProtKB P glucosinolate biosynthetic process from homomethionine
GO:0009753 IEP:TAIR P response to jasmonic acid
GO:0009611 IDA:TAIR P response to wounding

REACTOME Pathway Links

REACTOME Pathway ID Description
6253667 SLC-mediated transmembrane transport
6253668 Transmembrane transport of small molecules
6254194 Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds

Domain Information

InterPro Annotations

Accession Description
IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3

UniProt Annotations

Entry Information

Gene Name
probable sodium/metabolite cotransporter BASS5
Protein Entry
BASS5_ARATH
UniProt ID
F4JPW1
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=F4JPW1-1; Sequence=Displayed; Name=2; IsoId=F4JPW1-2; Sequence=VSP_044057; Note=No experimental confirmation available.;
Disruption Phenotype No visible phenotype under normal growth conditions, but plants contain reduced levels of aliphatic glucosinolates. {ECO:0000269|PubMed:19542295, ECO:0000269|PubMed:19633020}.
Function Plastidic transporter involved in the biosynthesis of aliphatic glucosinolates by translocating the biosynthetic intermediates of Met-derived glucosinolates across chloroplast membranes. Transports short chain (C2) alpha-keto acids, such as 4-methylsulfanyl-2-oxobutanoic acid, from the cytosol to the chloroplast where they are subjected to chain elongation cycles. Functions also in the transport of chain-elongated (C3 to C8) Met derivatives from the chloroplast to the cytosol. Does not seem to be involved in the transport of indole-derived glucosinolates. {ECO:0000269|PubMed:19542295, ECO:0000269|PubMed:19633020}.
Induction By wounding and methyl jasmonate (MeJa). Down-regulated by salicylic acid (SA). {ECO:0000269|PubMed:19542295}.
Sequence Caution Sequence=AAK91464.1; Type=Frameshift; Positions=127; Evidence={ECO:0000305}; Sequence=CAB40944.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB78246.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305|PubMed:19542295}; Multi-pass membrane protein {ECO:0000305|PubMed:19542295}. Plastid, chloroplast envelope {ECO:0000305|PubMed:19542295}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:19542295}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011051 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
42572883 RefSeq NP_974538 407 probable sodium/metabolite cotransporter BASS5
18413732 RefSeq NP_567385 273 probable sodium/metabolite cotransporter BASS5

Identical Sequences to LMP011051 proteins

Reference Database Accession Length Protein Name
GI:18413732 GenBank AAK91464.1 273 AT4g12030/F16J13_100 [Arabidopsis thaliana]
GI:18413732 GenBank AAM19874.1 273 AT3g20560/K10D20_9 [Arabidopsis thaliana]
GI:18413732 GenBank ACW85590.1 273 Sequence 1606 from patent US 7569389
GI:42572883 GenBank AEE83087.1 407 probable sodium/metabolite cotransporter BASS5 [Arabidopsis thaliana]
GI:18413732 GenBank AEE83088.1 273 probable sodium/metabolite cotransporter BASS5 [Arabidopsis thaliana]
GI:42572883 GenBank AGD27176.1 407 Sequence 24632 from patent US 8343764
GI:42572883 SwissProt F4JPW1.1 407 RecName: Full=Probable sodium/metabolite cotransporter BASS5, chloroplastic; AltName: Full=Bile acid transporter 5; AltName: Full=Bile acid-sodium symporter family protein 5; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP011051 proteins

Reference Database Accession Length Protein Name
GI:42572883 GenBank EFH48898.1 409 bile acid:sodium symporter family protein [Arabidopsis lyrata subsp. lyrata]
GI:18413732 GenBank AEE83087.1 407 probable sodium/metabolite cotransporter BASS5 [Arabidopsis thaliana]
GI:18413732 GenBank AGD27176.1 407 Sequence 24632 from patent US 8343764
GI:42572883 GenBank EOA22917.1 412 hypothetical protein CARUB_v10003651mg [Capsella rubella]
GI:18413732 RefSeq NP_974538.1 407 probable sodium/metabolite cotransporter BASS5 [Arabidopsis thaliana]
GI:42572883 RefSeq XP_002872639.1 409 bile acid:sodium symporter family protein [Arabidopsis lyrata subsp. lyrata]
GI:42572883 RefSeq XP_006290019.1 412 hypothetical protein CARUB_v10003651mg [Capsella rubella]
GI:18413732 RefSeq XP_010433847.1 409 PREDICTED: probable sodium/metabolite cotransporter BASS5, chloroplastic isoform X1 [Camelina sativa]
GI:42572883 RefSeq XP_010433847.1 409 PREDICTED: probable sodium/metabolite cotransporter BASS5, chloroplastic isoform X1 [Camelina sativa]
GI:18413732 RefSeq XP_010433855.1 400 PREDICTED: probable sodium/metabolite cotransporter BASS5, chloroplastic isoform X2 [Camelina sativa]
GI:42572883 RefSeq XP_010422170.1 409 PREDICTED: probable sodium/metabolite cotransporter BASS5, chloroplastic isoform X1 [Camelina sativa]
GI:18413732 SwissProt F4JPW1.1 407 RecName: Full=Probable sodium/metabolite cotransporter BASS5, chloroplastic; AltName: Full=Bile acid transporter 5; AltName: Full=Bile acid-sodium symporter family protein 5; Flags: Precursor [Arabidopsis thaliana]