Gene/Proteome Database (LMPD)

LMPD ID
LMP011060
Gene ID
839094
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
Gene Symbol
AT1G25054
Synonyms
F5A9.8; F5A9_8
Alternate Names
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
Chromosome
1
EC Number
3.5.1.-

Proteins

UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
Refseq ID NP_173884
Protein GI 240254165
UniProt ID P0DKB8
mRNA ID NM_102322
Length 369
RefSeq Status REVIEWED
MLQIRIKKAKSAIRSHLFIGKDLALLLEIISDPAFYPIEDVESMRLPVTVKATKPSFLVIWIRYSSAASSPTVSLNPSGRLQQTLAGSVEVKGKSLHSGKFSTVKLNPEIAGAGRFFEFRSRFIPASIEFAQESPLCTTLLKDELKIRTVEHLLSALEAKGVDNCRIQIESESSDDREVEVPIFDGSAKEWVDAIQGVGINAAQNHDGESVEKMVAHVNKPVYVCKNDTFVAAFPALETRITCGIDFPQVPAIGCQWFSWRPIHESSFAKDIASSRTFCVYEEVERMREAGLIKGGSLDNAIVCSAEHGWMNPPLRFDDEACRHKILDLIGDLSLVSRGGNGGLPVAHIVAYKAGHALHTDLARHLTMD
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
Refseq ID NP_001117349
Protein GI 240254167
UniProt ID P0DKB9
mRNA ID NM_001123877
Length 326
RefSeq Status REVIEWED
MRLPVTVKATKPSFLVIWIRYSSAASSPTVSLNPSGRLQQTLAGSVEVKGKSLHSGKFSTVKLNPEIAGAGRFFEFRSRFIPASIEFAQESPLCTTLLKDELKIRTVEHLLSALEAKGVDNCRIQIESESSDDREVEVPIFDGSAKEWVDAIQGVGINAAQNHDGESVEKMVAHVNKPVYVCKNDTFVAAFPALETRITCGIDFPQVPAIGCQWFSWRPIHESSFAKDIASSRTFCVYEEVERMREAGLIKGGSLDNAIVCSAEHGWMNPPLRFDDEACRHKILDLIGDLSLVSRGGNGGLPVAHIVAYKAGHALHTDLARHLTMD

Gene Information

Entrez Gene ID
839094
Gene Name
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
Gene Symbol
AT1G25054
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:UniProtKB C mitochondrion
GO:0008759 IMP:UniProtKB F UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GO:0009245 IEA:UniProtKB-KW P lipid A biosynthetic process
GO:2001289 IMP:UniProtKB P lipid X metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR020568 Ribosomal protein S5 domain 2-type fold
IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase
IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal
IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal

UniProt Annotations

Entry Information

Gene Name
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
Protein Entry
LPXC1_ARATH
UniProt ID
P0DKB9
Species
Arabidopsis

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=F4IAT8-1; Sequence=Displayed; Name=2; IsoId=F4IAT8-2; Sequence=VSP_022944, VSP_022945; Note=May be due to a competing donor splice site. No experimental confirmation available.; Name=3; IsoId=F4IAT8-3; Sequence=VSP_034100; Note=May be due to intron retention. No experimental confirmation available.;
Catalytic Activity UDP-3-O-(3-hydroxytetradecanoyl)-N- acetylglucosamine + H(2)O = UDP-3-O-(3-hydroxytetradecanoyl)- glucosamine + acetate.
Function Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential). {ECO:0000305}.
Miscellaneous Plants silencing LPXC do not have altered morphology compared to wild-type plants when grown under normal growth conditions, but they do not accumulate 2,3- diacylglucosamine-1-phosphate. {ECO:0000305|PubMed:21709257}.
Pathway Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. {ECO:0000269|PubMed:21709257}.
Sequence Caution Sequence=AAG03124.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At1g24793 and At1g24800.; Evidence={ECO:0000305};
Similarity Belongs to the LpxC family. {ECO:0000305}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:21709257}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011060 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
240254165 RefSeq NP_173884 369 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
240254167 RefSeq NP_001117349 326 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase

Identical Sequences to LMP011060 proteins

Reference Database Accession Length Protein Name
GI:240254165 GenBank AEE30567.1 369 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254165 GenBank AEE30573.1 369 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254165 RefSeq NP_173878.6 369 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254167 RefSeq NP_001185090.1 326 UDP-3-O-acyl N-acetylglycosamine deacetylase family protein [Arabidopsis thaliana]
GI:240254167 SwissProt P0DKB7.1 326 RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2; AltName: Full=Protein LIPID X C2; Short=AtLpxC2; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 2; Flags: Precursor [Arabidopsis thaliana]
GI:240254167 SwissProt P0DKB8.1 326 RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3; AltName: Full=Protein LIPID X C3; Short=AtLpxC3; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 3; Flags: Precursor [Arabidopsis thaliana]
GI:240254167 SwissProt P0DKB9.1 326 RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 4; AltName: Full=Protein LIPID X C4; Short=AtLpxC4; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 4; Flags: Precursor [Arabidopsis thaliana]
GI:240254167 SwissProt F4IAT8.2 326 RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1; AltName: Full=Protein LIPID X C1; Short=AtLpxC1; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 1; Flags: Precursor [Arabidopsis thaliana]
GI:240254167 SwissProt F4IAW1.2 326 RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5; AltName: Full=Protein LIPID X C5; Short=AtLpxC5; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 5; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP011060 proteins

Reference Database Accession Length Protein Name
GI:240254165 GenBank AEE30562.1 326 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254167 GenBank AEE30567.1 369 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254167 GenBank AEE30573.1 369 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254165 GenBank AEE30574.1 326 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254165 GenBank AEE30582.1 326 UDP-3-O-acyl N-acetylglycosamine deacetylase family protein [Arabidopsis thaliana]
GI:240254167 GenBank AEE30586.1 371 probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5 [Arabidopsis thaliana]
GI:240254165 GenBank AEE30586.1 371 probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5 [Arabidopsis thaliana]
GI:240254165 RefSeq NP_173874.2 326 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254167 RefSeq NP_173884.5 369 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254167 RefSeq NP_173878.6 369 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana]
GI:240254167 RefSeq NP_849706.3 371 probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5 [Arabidopsis thaliana]
GI:240254165 RefSeq NP_849706.3 371 probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5 [Arabidopsis thaliana]