Gene/Proteome Database (LMPD)

LMPD ID
LMP011143
Gene ID
822389
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
ARM repeat superfamily protein
Gene Symbol
RST1
Synonyms
RESURRECTION1; RST1
Alternate Names
ARM repeat superfamily protein
Chromosome
3
Summary
A novel protein, did not show high similarity to any protein of known function; reveals a novel genetic connection between lipid synthesis and embryo development. Expressed in all tissues examined including leaves, flowers, roots, stems, and siliques, but accumulation levels were not correlated with the degree to which different organs appeared affected by the mutation. Mutant plants showed alterations in the cuticular wax profiles and embryo development.
Orthologs
View orthologs and multiple alignments for RST1

Proteins

ARM repeat superfamily protein
Refseq ID NP_189404
Protein GI 42565251
UniProt ID Q7XZF5
mRNA ID NM_113683
Length 1841
RefSeq Status REVIEWED
MASYATLLEKTRVPQPSIQRFAVISVFSKLRSAPEQFGSEAEAGREAISFCLTSESITVVDQSVHELCRLVSDSVLDLSRGLLELQSALEGCDSKLVSLFVKGLGFLIRIGYERNNGNWKFNSTENHPFVRIQSSRVETQTELLHQVSLFVMHNRRLGMVGVCEFLEPFLNFTILRIPLSDSSSSLFARELISSMASLCCSSRHEALPIFRLLMRCLKYIPGNNLEVIVKILVDAYTVVVRDLVGTGLEVTEVHLLGVQLVDGVLFLCASPHVQTTEQESVIESLKHLLAVQKDLGLAYSHDLSLVVLSLVFMLAKSTVEHEQLCILKFLLFLLKWKTESENLSVKDAAGSSVESLLLFPITALMSSPSKSIKVAASKVLSIVENFLVTVSNAPKIEVHTSKGDSPLSRVGSVVFRFMQQLWHQNDYTPSTSSFLRVAYTNGSEKQETYLGPVTWNSLLREHAERFWDKKKLSASFCLSQEIPILLGAVAGVMVMHPSLGADAIGSLTIIGGIDSKMSVPLLLAVLYFSNLLSRTNVPCQSLLSKLLGLLPSLAAQQVMIPLVVQTITPMLRKDAKGLLYATAIRLLCQTWVVNDRAFSSLQEVLRPQGFIEYISERHICISMAASIHDVCKRHPDRGVDLILSVQACIESQNCPVRALGFQSLSHLCEADVIDFYTAWDVIKKHAQHIKLDPLLAYSVCHLLKWGAMDAEAYPEDAENVLNILWEIGSSMQKPHDSQWTKARVSAIVALGQYEVSFMENKFSDFNKNCTYLLFSETNAEILNALEDLSIKIMIHEHSVRRRYVREKKVPGSKIEKLLDVIPQVIFPAGKEIKTGELPGAALLCLSYNPRDVKFGSSRSFHDVHFQYEEAFRVVVKSLQLSRNISLALISLQSLKAFMRRWMRANILSIDATTKELSSDKTSKATNNIMKSLVHMAEEALPRCAENIALALGALCAALPAASHNIKASASKFLLSWLLEHEHEHRQWTAGISLGLISSSLHVTDHKQKFQNISGLLEVLCSSKSTLVKGACGVGLGFSCQDLLTRTEASASSDIDSDSYRNQEERLLGRIVRLLSSILHGFLHTPCDILESLSALFPPGEEDNVIGLPQLLDESSDDFDDDTWGIAGLIIGLGMSVGAIYRAGKKDAVVKIKNLIVSWIPYADSLKQTSGSNSKVSVRLFSVGSCLALPIVITFCQKVELFDAHEVDDIIGCFKDLISELLIVRKSGALRKRLLMASCIGAGDLLGSVLNEGIHPVKIESVKELLELFKKCYSGLYPPVAHFGGMLGVVNVLGAGAGNLVYSHPRPRAPPASSEENEISYVSGPLLSNAYFTQQLTPVVQEIFLIAQNTKDRQLQHYAAWAISILRTYMRSGESSSLSNENQSDDSDRNSISHNVPEHTMVMKLAQGLTNPSFPLAGSPLNIGTMASALRCLSHAPRLPNLDWGATIRRLMKQETQTDVTQSGDVPKEITLREECFKFSLAHASEFDELLAFLDELSELSRFKALEESLQSCLLCHLGGLMRIFSGSRMNKLFDDVSCFVVSLSSDQTYSCDQKSSLRVSCWKGLSQCLEETSLESSEYVTKIEKCIELLFAVLPVASQSPRADQMGSVKEWSEAVTCLQKSHRDWLYKFLQVSNLEPGNEKTNFQGDLKKIQAKAKLAKLGSVPFSELGKLKAIILNCEESDIWDVLIEIVAALHHAEGGIKRQWLIDAVEISCVSSHPSTAIIFVGLLSSICCEYMPFLNLDRSTVLSDMSVTVTSLLSDPSYEVVTEPFISFLWTSLERVYSFATESDANARLSSQQIAQSERDKAPMLVKVMHYICVAFRDHLPLEKQLRLASMDMS

Gene Information

Entrez Gene ID
822389
Gene Name
ARM repeat superfamily protein
Gene Symbol
RST1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IEA:UniProtKB-KW C plasma membrane
GO:0043447 IMP:UniProtKB P alkane biosynthetic process
GO:0006952 IEA:UniProtKB-KW P defense response
GO:0006629 IEA:UniProtKB-KW P lipid metabolic process
GO:0048316 IMP:UniProtKB P seed development

Domain Information

InterPro Annotations

Accession Description
IPR016024 Armadillo-type fold
IPR022542 Domain of unknown function DUF3730

UniProt Annotations

Entry Information

Gene Name
ARM repeat superfamily protein
Protein Entry
RST1_ARATH
UniProt ID
Q7XZF5
Species
Arabidopsis

Comments

Comment Type Description
Disruption Phenotype Shrunken non viable seeds due to arrested embryo development when homozygous. Alteration in cuticular waxes with elevated amounts of cutin monomers in leaves. Susceptibility to the obligate biotrophic fungus E.cichoracearum and increased resistance to the necrotrophic fungi B.cinerea and A.brassicicola. {ECO:0000269|PubMed:16183838, ECO:0000269|PubMed:19625635}.
Function Involved in cuticular wax formation. Required for the synthesis of alkanes from wax precursors. May play a role in acyl- CoA reduction to aldehydes. {ECO:0000269|PubMed:16183838, ECO:0000269|PubMed:19625635}.
Sequence Caution Sequence=BAB02691.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Subcellular Location Cell membrane {ECO:0000305|PubMed:19625635}; Multi-pass membrane protein {ECO:0000305|PubMed:19625635}.
Tissue Specificity Expressed in the vasculature of leaves, petioles and hypocotyls, anthers of mature flowers and siliques. Expressed at low levels in roots and stems. {ECO:0000269|PubMed:16183838, ECO:0000269|PubMed:19625635}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011143 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
42565251 RefSeq NP_189404 1841 ARM repeat superfamily protein

Identical Sequences to LMP011143 proteins

Reference Database Accession Length Protein Name
GI:42565251 GenBank AEE77350.1 1841 ARM repeat superfamily protein [Arabidopsis thaliana]
GI:42565251 SwissProt Q7XZF5.2 1841 RecName: Full=Protein RST1; AltName: Full=Protein RESURRECTION 1 [Arabidopsis thaliana]

Related Sequences to LMP011143 proteins

Reference Database Accession Length Protein Name
GI:42565251 DBBJ BAB02691.1 1868 unnamed protein product [Arabidopsis thaliana]
GI:42565251 GenBank AAP74222.1 1841 RST1 [Arabidopsis thaliana]
GI:42565251 GenBank EFH51655.1 1847 hypothetical protein ARALYDRAFT_484555 [Arabidopsis lyrata subsp. lyrata]
GI:42565251 RefSeq XP_002875396.1 1847 hypothetical protein ARALYDRAFT_484555 [Arabidopsis lyrata subsp. lyrata]
GI:42565251 RefSeq XP_010502773.1 1849 PREDICTED: protein RST1 [Camelina sativa]
GI:42565251 RefSeq XP_010514478.1 1846 PREDICTED: protein RST1-like [Camelina sativa]