Gene/Proteome Database (LMPD)

LMPD ID
LMP011196
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
putative geranylgeranyl pyrophosphate synthase 8
Gene Symbol
Alternate Names
putative geranylgeranyl pyrophosphate synthase 8
Chromosome
3
EC Number
2.5.1.-

Proteins

putative geranylgeranyl pyrophosphate synthase 8
Refseq ID NP_188069
Protein GI 15231869
UniProt ID Q9LRR0
mRNA ID NM_112311
Length 284
RefSeq Status REVIEWED
MRLSTFRSVPLREPLTVQEAVRYSLLAGGKRVRPLLCIAVCELVGGDEATAMSAACAVEMIHTSSLIHDDLPCMDNADLRRGKPTNHKVFGEDMAVLAGDALLALAFEHMTVVSSGLVASERMIRAVVELARAIGTKGLVAGQVVDLSSERLNPHDVGLERLEFIHLHKTAALLEAAAVIGAIMGGGTEEEIEKLRKYARCIGLLFQVVDDILDVTKSTEELGKTAGKDVMAGKLTYPRLIGLERSREVAEKLSREAEEQLLGFESDKAAPLVALASYISCRND

Gene Information

Entrez Gene ID
Gene Name
putative geranylgeranyl pyrophosphate synthase 8
Gene Symbol
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IEA:UniProtKB-KW C chloroplast
GO:0004161 IEA:UniProtKB-EC F dimethylallyltranstransferase activity
GO:0004311 IEA:UniProtKB-EC F farnesyltranstransferase activity
GO:0004337 IEA:UniProtKB-EC F geranyltranstransferase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0016117 IEA:UniProtKB-KW P carotenoid biosynthetic process
GO:0045337 IEA:UniProtKB-UniPathway P farnesyl diphosphate biosynthetic process
GO:0033384 IEA:UniProtKB-UniPathway P geranyl diphosphate biosynthetic process
GO:0033386 IEA:UniProtKB-UniPathway P geranylgeranyl diphosphate biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath01100 Metabolic pathways
ath00900 Terpenoid backbone biosynthesis
ko00900 Terpenoid backbone biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR008949 Isoprenoid synthase domain
IPR000092 Polyprenyl synthetase
IPR017446 Polyprenyl synthetase-related

UniProt Annotations

Entry Information

Gene Name
putative geranylgeranyl pyrophosphate synthase 8
Protein Entry
GGPP8_ARATH
UniProt ID
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
Catalytic Activity Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
Catalytic Activity Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)-farnesyl diphosphate.
Caution Could be the product of a pseudogene. {ECO:0000305}.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 3 Mg(2+) ions per subunit. {ECO:0000250};
Function Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate. {ECO:0000250}.
Pathway Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
Pathway Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
Pathway Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1.
Sequence Caution Sequence=AEE75533.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AEE75533.1; Type=Frameshift; Positions=85; Evidence={ECO:0000305}; Sequence=BAB01343.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAB01343.1; Type=Frameshift; Positions=85; Evidence={ECO:0000305};
Similarity Belongs to the FPP/GGPP synthase family. {ECO:0000305}.
Subcellular Location Plastid, chloroplast {ECO:0000305}.
Subunit Monomer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011196 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15231869 RefSeq NP_188069 284 putative geranylgeranyl pyrophosphate synthase 8

Identical Sequences to LMP011196 proteins

Reference Database Accession Length Protein Name
GI:15231869 GenBank AEE75533.1 284 putative geranylgeranyl pyrophosphate synthase 8 [Arabidopsis thaliana]

Related Sequences to LMP011196 proteins

Reference Database Accession Length Protein Name
GI:15231869 DBBJ BAB02387.1 360 geranylgeranyl pyrophosphate synthase [Arabidopsis thaliana]
GI:15231869 DBBJ BAB01343.1 306 geranyl geranyl pyrophosphate synthase-like protein [Arabidopsis thaliana]
GI:15231869 EMBL CBF64798.1 306 unnamed protein product [Arabidopsis thaliana]
GI:15231869 EMBL CBU89669.1 306 unnamed protein product [Arabidopsis thaliana]
GI:15231869 GenBank AGX56671.1 306 Sequence 13680 from patent US 8541208
GI:15231869 SwissProt Q9LRR0.2 361 RecName: Full=Putative geranylgeranyl pyrophosphate synthase 8, chloroplastic; Short=GGPP synthase 8; Short=GGPS8; AltName: Full=(2E,6E)-farnesyl diphosphate synthase 8; AltName: Full=Dimethylallyltranstransferase 8; AltName: Full=Farnesyl diphosphate synthase 8; AltName: Full=Farnesyltranstransferase 8; AltName: Full=Geranyltranstransferase 8; Flags: Precursor [Arabidopsis thaliana]