Gene/Proteome Database (LMPD)

LMPD ID
LMP011213
Gene ID
841525
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
phosphatidylinositol 4-kinase alpha 2
Gene Symbol
AT1G51040
Synonyms
F23H24.10; F23H24_10
Alternate Names
phosphatidylinositol 4-kinase alpha 2
Chromosome
1
EC Number
2.7.1.67

Proteins

phosphatidylinositol 4-kinase alpha 2
Refseq ID NP_175516
Protein GI 15223705
UniProt ID Q9C680
mRNA ID NM_103983
Length 525
RefSeq Status REVIEWED
MERLNELCDIIEQNPKQFLDKLPWICQQCPQSKLLRAESPRFSQSHLNAILAVTRILSKIVDTTDENAKFVVLDFLQTVPKSFHRSFWPYSLSLESISAFYCSFLGYVSCLSQLMVEGYLLRAAQRSDIFAHTLIWHLQGESVEEIVKDGAFDKNASFQEILSDVRQHIVDGFTPKALNFFSREFDFFEKVTSISGALLPLPKEERVAGIRRELEKIKMQGEDLYLPTAPNKLVRVIQVDSGIPLQSAAKVPIMITFNVVDLDGDHNDVKPQACIFKVGDDCRQDVLALQVISLLGDIFQAVGLNLYLFPYGVLPTVVPNTRSRSQMGETTDGGLYEIFQQNYGLVGSTTFETARANFLISSAGYAVASLLLQPKDRHNGNLLFDDVGRLVHIDFGFILETSPGGNMRFENAHFKLSHEMTQLLDPSGVMKSKTWHQFVSLCVKGYLAARRYMDEIISTVQMMLESGLPCFSRGDPIGNLRKRFHPEMSEREAALFMINVCTDAYNKWTTAGYDLIQYLQQGVEK

Gene Information

Entrez Gene ID
841525
Gene Name
phosphatidylinositol 4-kinase alpha 2
Gene Symbol
AT1G51040
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IDA:TAIR C chloroplast
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0004430 ISS:UniProtKB F 1-phosphatidylinositol 4-kinase activity
GO:0048015 IEA:InterPro P phosphatidylinositol-mediated signaling

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6352 3-phosphoinositide biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
6254334 PI Metabolism
6254336 Synthesis of PIPs at the ER membrane
6254337 Synthesis of PIPs at the Golgi membrane

Domain Information

InterPro Annotations

Accession Description
IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
IPR015433 Phosphatidylinositol Kinase
IPR011009 Protein kinase-like domain

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol 4-kinase alpha 2
Protein Entry
P4KA2_ARATH
UniProt ID
Q9C680
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate.
Function Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate. {ECO:0000250}.
Similarity Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. {ECO:0000305}.
Similarity Contains 1 PI3K/PI4K domain. {ECO:0000255|PROSITE- ProRule:PRU00269}.
Subcellular Location Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011213 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15223705 RefSeq NP_175516 525 phosphatidylinositol 4-kinase alpha 2

Identical Sequences to LMP011213 proteins

Reference Database Accession Length Protein Name
GI:15223705 GenBank AAG50530.1 525 phosphatidylinositol 4-kinase, putative [Arabidopsis thaliana]
GI:15223705 GenBank AEE32615.1 525 phosphatidylinositol 4-kinase alpha 2 [Arabidopsis thaliana]
GI:15223705 SwissProt Q9C680.1 525 RecName: Full=Phosphatidylinositol 4-kinase alpha 2; Short=PI4-kinase alpha 2; Short=PtdIns-4-kinase alpha 2; AltName: Full=Phosphatidylinositol 4-OH kinase alpha2; Short=AtPI4Kalpha2; Short=PI-4Kalpha2 [Arabidopsis thaliana]

Related Sequences to LMP011213 proteins

Reference Database Accession Length Protein Name
GI:15223705 GenBank EOA36778.1 1894 hypothetical protein CARUB_v10008074mg [Capsella rubella]
GI:15223705 GenBank ESQ30552.1 2028 hypothetical protein EUTSA_v10011177mg [Eutrema salsugineum]
GI:15223705 RefSeq XP_006303880.1 1894 hypothetical protein CARUB_v10008074mg [Capsella rubella]
GI:15223705 RefSeq XP_006393266.1 2028 hypothetical protein EUTSA_v10011177mg [Eutrema salsugineum]
GI:15223705 RefSeq XP_010463373.1 1908 PREDICTED: phosphatidylinositol 4-kinase alpha 1-like [Camelina sativa]
GI:15223705 RefSeq XP_010479560.1 1946 PREDICTED: phosphatidylinositol 4-kinase alpha 1-like [Camelina sativa]