Gene/Proteome Database (LMPD)

LMPD ID
LMP011230
Gene ID
839891
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
pyruvate dehydrogenase E1 beta
Gene Symbol
PDH-E1 BETA
Synonyms
pyruvate dehydrogenase E1 beta
Alternate Names
pyruvate dehydrogenase E1 beta
Chromosome
1
EC Number
1.2.4.1
Summary
Encodes a putative plastid pyruvate dehydrogenase E1 beta subunit that is distinct from the mitochondrial pyruvate dehydrogenase E1 beta subunit.
Orthologs
View orthologs and multiple alignments for PDH-E1 BETA

Proteins

pyruvate dehydrogenase E1 beta
Refseq ID NP_174304
Protein GI 15220670
UniProt ID Q9C6Z3
mRNA ID NM_102751
Length 406
RefSeq Status REVIEWED
MSSIIHGAGAATTTLSTFNSVDSKKLFVAPSRTNLSVRSQRYIVAGSDASKKSFGSGLRVRHSQKLIPNAVATKEADTSASTGHELLLFEALQEGLEEEMDRDPHVCVMGEDVGHYGGSYKVTKGLADKFGDLRVLDTPICENAFTGMGIGAAMTGLRPVIEGMNMGFLLLAFNQISNNCGMLHYTSGGQFTIPVVIRGPGGVGRQLGAEHSQRLESYFQSIPGIQMVACSTPYNAKGLMKAAIRSENPVILFEHVLLYNLKEKIPDEDYVCNLEEAEMVRPGEHITILTYSRMRYHVMQAAKTLVNKGYDPEVIDIRSLKPFDLHTIGNSVKKTHRVLIVEECMRTGGIGASLTAAINENFHDYLDAPVMCLSSQDVPTPYAGTLEEWTVVQPAQIVTAVEQLCQ

Gene Information

Entrez Gene ID
839891
Gene Name
pyruvate dehydrogenase E1 beta
Gene Symbol
PDH-E1 BETA
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IDA:TAIR C chloroplast
GO:0009941 IDA:TAIR C chloroplast envelope
GO:0009570 IDA:TAIR C chloroplast stroma
GO:0010240 TAS:TAIR C plastid pyruvate dehydrogenase complex
GO:0004739 TAS:TAIR F pyruvate dehydrogenase (acetyl-transferring) activity
GO:0006633 TAS:TAIR P fatty acid biosynthetic process
GO:0006096 IEA:UniProtKB-KW P glycolytic process

KEGG Pathway Links

KEGG Pathway ID Description
ath01200 Carbon metabolism
ath00020 Citrate cycle (TCA cycle)
ath00010 Glycolysis / Gluconeogenesis
ath_M00307 Pyruvate oxidation, pyruvate => acetyl-CoA

Domain Information

InterPro Annotations

Accession Description
IPR029061 Thiamin diphosphate-binding fold
IPR005476 Transketolase, C-terminal
IPR009014 Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II
IPR005475 Transketolase-like, pyrimidine-binding domain

UniProt Annotations

Entry Information

Gene Name
pyruvate dehydrogenase E1 beta
Protein Entry
ODPB2_ARATH
UniProt ID
Q9C6Z3
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2).
Cofactor Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250};
Function The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). {ECO:0000250}.
Subcellular Location Plastid, chloroplast {ECO:0000305}.
Subunit Tetramer of 2 alpha and 2 beta subunits. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011230 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15220670 RefSeq NP_174304 406 pyruvate dehydrogenase E1 beta

Identical Sequences to LMP011230 proteins

Reference Database Accession Length Protein Name
GI:15220670 EMBL CCA64977.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 EMBL CCA78237.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 EMBL CCA78599.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 EMBL CDH47860.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 EMBL CDI44196.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 GenBank AEE31181.1 406 pyruvate dehydrogenase E1 beta [Arabidopsis thaliana]

Related Sequences to LMP011230 proteins

Reference Database Accession Length Protein Name
GI:15220670 EMBL CCA64616.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 EMBL CCA64978.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 EMBL CCA78238.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 EMBL CCA78600.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 EMBL CDI44197.1 406 unnamed protein product [Arabidopsis thaliana]
GI:15220670 GenBank AAB86804.1 406 pyruvate dehydrogenase E1 beta subunit [Arabidopsis thaliana]