Gene/Proteome Database (LMPD)
LMPD ID
LMP011239
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
receptor-like protein kinase HERK 1
Gene Symbol
Synonyms
hercules receptor kinase 1; HERK1
Alternate Names
receptor-like protein kinase HERK 1
Chromosome
3
EC Number
2.7.11.-
Summary
Encodes HERCULES1 (HERK1), a receptor kinase regulated by Brassinosteroids and required for cell elongation during vegetative growth.
Orthologs
Proteins
| receptor-like protein kinase HERK 1 | |
|---|---|
| Refseq ID | NP_190214 |
| Protein GI | 15231393 |
| UniProt ID | Q9LX66 |
| mRNA ID | NM_114497 |
| Length | 830 |
| RefSeq Status | REVIEWED |
| MGIEKFETFILISTISILLCICHGFTPVDNYLINCGSPTNGTLMGRIFLSDKLSSKLLTSSKEILASVGGNSGSDIYHTARVFTEVSSYKFSVTRGRHWVRLYFNPFDYQNFKMGSAKFAVSSQSHVLLSDFTVTSSKVVKEYSLNVTTNDLVLTFTPSSGSFAFVNAIEVISIPDTLITGSPRFVGNPAQFPDMSMQGLETIHRVNMGGPLVASNNDTLTRTWVPDSEFLLEKNLAKSMSKFSTVNFVPGYATEDSAPRTVYGSCTEMNSADNPNSIFNVTWEFDVDPGFQYYFRFHFCDIVSLSLNQLYFNLYVDSMVAATDIDLSTLVDNTLAGAYSMDFVTQTPKGSNKVRVSIGPSTVHTDYPNAIVNGLEIMKMNNSKGQLSTGTFVPGSSSSSKSNLGLIVGSAIGSLLAVVFLGSCFVLYKKRKRGQDGHSKTWMPFSINGTSMGSKYSNGTTLTSITTNANYRIPFAAVKDATNNFDESRNIGVGGFGKVYKGELNDGTKVAVKRGNPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENNEMILIYEYMENGTVKSHLYGSGLPSLTWKQRLEICIGAARGLHYLHTGDSKPVIHRDVKSANILLDENFMAKVADFGLSKTGPELDQTHVSTAVKGSFGYLDPEYFRRQQLTDKSDVYSFGVVLFEVLCARPVIDPTLPREMVNLAEWAMKWQKKGQLDQIIDQSLRGNIRPDSLRKFAETGEKCLADYGVDRPSMGDVLWNLEYALQLQEAVIDGEPEDNSTNMIGELPPQINNFSQGDTSVNVPGTAGRFEESSIDDLSGVSMSKVFSQLVKSEGR | |
Gene Information
Entrez Gene ID
Gene Name
receptor-like protein kinase HERK 1
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0005886 | IDA:TAIR | C | plasma membrane |
| GO:0009506 | IDA:TAIR | C | plasmodesma |
| GO:0005524 | IEA:UniProtKB-KW | F | ATP binding |
| GO:0004672 | IDA:TAIR | F | protein kinase activity |
| GO:0004674 | IEA:UniProtKB-KW | F | protein serine/threonine kinase activity |
| GO:0009742 | IGI:TAIR | P | brassinosteroid mediated signaling pathway |
| GO:0009791 | IGI:TAIR | P | post-embryonic development |
| GO:0051510 | IGI:TAIR | P | regulation of unidimensional cell growth |
| GO:0009741 | IGI:TAIR | P | response to brassinosteroid |
| GO:0009826 | IGI:TAIR | P | unidimensional cell growth |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR013320 | Concanavalin A-like lectin/glucanase domain |
| IPR024788 | Malectin-like carbohydrate-binding domain |
| IPR000719 | Protein kinase domain |
| IPR017441 | Protein kinase, ATP binding site |
| IPR011009 | Protein kinase-like domain |
| IPR001245 | Serine-threonine/tyrosine-protein kinase catalytic domain |
| IPR008271 | Serine/threonine-protein kinase, active site |
UniProt Annotations
Entry Information
Gene Name
receptor-like protein kinase HERK 1
Protein Entry
HERK_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Disruption Phenotype | No visible phenotype; due to redundancy with THE1. Herk1 and the1 double mutants are stunted. In herk1-1, shorter hypocotyls without brassinolide (BL) treatment than with BL treatment. {ECO:0000269|PubMed:19383785}. |
| Function | Receptor-like protein kinase required for cell elongation during vegetative growth, mostly in a brassinosteroid- (BR-) independent manner. {ECO:0000269|PubMed:19383785}. |
| Induction | By brassinosteroids (BR). {ECO:0000269|PubMed:19383785}. |
| Ptm | Autophosphorylated. |
| Sequence Caution | Sequence=CAB62020.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; |
| Similarity | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}. |
| Similarity | Contains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:17644812, ECO:0000269|PubMed:19383785}; Single-pass type I membrane protein {ECO:0000269|PubMed:17644812, ECO:0000269|PubMed:19383785}. |
| Tissue Specificity | Expressed in most vegetative tissues, including leaves, stems and roots, especially in cell elongation regions. {ECO:0000269|PubMed:19383785}. |
| Web Resource | Name=PlantP kinase Classification PPC; URL="http://plantsp.genomics.purdue.edu/family/class.html"; |
Identical and Related Proteins
Unique RefSeq proteins for LMP011239 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 15231393 | RefSeq | NP_190214 | 830 | receptor-like protein kinase HERK 1 |
Identical Sequences to LMP011239 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15231393 | EMBL | CAW34784.1 | 830 | unnamed protein product [Arabidopsis thaliana] |
| GI:15231393 | EMBL | CAW43131.1 | 830 | unnamed protein product [Arabidopsis thaliana] |
| GI:15231393 | EMBL | CBC08659.1 | 830 | unnamed protein product [Arabidopsis thaliana] |
| GI:15231393 | EMBL | CBC00819.1 | 830 | unnamed protein product [Arabidopsis thaliana] |
| GI:15231393 | EMBL | CBC05549.1 | 830 | unnamed protein product [Arabidopsis thaliana] |
| GI:15231393 | GenBank | AEE78143.1 | 830 | receptor-like protein kinase HERK 1 [Arabidopsis thaliana] |
Related Sequences to LMP011239 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15231393 | GenBank | EFH52036.1 | 829 | hypothetical protein ARALYDRAFT_905825 [Arabidopsis lyrata subsp. lyrata] |
| GI:15231393 | GenBank | EOA23497.1 | 829 | hypothetical protein CARUB_v10016688mg [Capsella rubella] |
| GI:15231393 | RefSeq | XP_002875777.1 | 829 | hypothetical protein ARALYDRAFT_905825 [Arabidopsis lyrata subsp. lyrata] |
| GI:15231393 | RefSeq | XP_006290599.1 | 829 | hypothetical protein CARUB_v10016688mg [Capsella rubella] |
| GI:15231393 | RefSeq | XP_010503244.1 | 830 | PREDICTED: receptor-like protein kinase HERK 1 [Camelina sativa] |
| GI:15231393 | RefSeq | XP_010514960.1 | 830 | PREDICTED: receptor-like protein kinase HERK 1 isoform X2 [Camelina sativa] |