Gene/Proteome Database (LMPD)

LMPD ID
LMP011240
Gene ID
835526
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
receptor-like protein kinase THESEUS 1
Gene Symbol
THE1
Synonyms
GA469.3; GA469_3; THE1; THESEUS1
Alternate Names
receptor-like protein kinase THESEUS 1
Chromosome
5
EC Number
2.7.11.-

Proteins

receptor-like protein kinase THESEUS 1
Refseq ID NP_200249
Protein GI 15239630
UniProt ID Q9LK35
mRNA ID NM_124818
Length 855
RefSeq Status REVIEWED
MVFTKSLLVLLWFLSCYTTTTSSALFNPPDNYLISCGSSQNITFQNRIFVPDSLHSSLVLKIGNSSVATSTTSNNSTNSIYQTARVFSSLASYRFKITSLGRHWIRLHFSPINNSTWNLTSASITVVTEDFVLLNNFSFNNFNGSYIFKEYTVNVTSEFLTLSFIPSNNSVVFVNAIEVVSVPDNLIPDQALALNPSTPFSGLSLLAFETVYRLNMGGPLLTSQNDTLGRQWDNDAEYLHVNSSVLVVTANPSSIKYSPSVTQETAPNMVYATADTMGDANVASPSFNVTWVLPVDPDFRYFVRVHFCDIVSQALNTLVFNLYVNDDLALGSLDLSTLTNGLKVPYFKDFISNGSVESSGVLTVSVGPDSQADITNATMNGLEVLKISNEAKSLSGVSSVKSLLPGGSGSKSKKKAVIIGSLVGAVTLILLIAVCCYCCLVASRKQRSTSPQEGGNGHPWLPLPLYGLSQTLTKSTASHKSATASCISLASTHLGRCFMFQEIMDATNKFDESSLLGVGGFGRVYKGTLEDGTKVAVKRGNPRSEQGMAEFRTEIEMLSKLRHRHLVSLIGYCDERSEMILVYEYMANGPLRSHLYGADLPPLSWKQRLEICIGAARGLHYLHTGASQSIIHRDVKTTNILLDENLVAKVADFGLSKTGPSLDQTHVSTAVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLMEVLCCRPALNPVLPREQVNIAEWAMAWQKKGLLDQIMDSNLTGKVNPASLKKFGETAEKCLAEYGVDRPSMGDVLWNLEYALQLEETSSALMEPDDNSTNHIPGIPMAPMEPFDNSMSIIDRGGVNSGTGTDDDAEDATTSAVFSQLVHPRGR

Gene Information

Entrez Gene ID
835526
Gene Name
receptor-like protein kinase THESEUS 1
Gene Symbol
THE1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IDA:TAIR C plasma membrane
GO:0009506 IDA:TAIR C plasmodesma
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004672 IDA:TAIR F protein kinase activity
GO:0004674 IEA:UniProtKB-KW F protein serine/threonine kinase activity
GO:0009742 IGI:TAIR P brassinosteroid mediated signaling pathway
GO:0009791 IGI:TAIR P post-embryonic development
GO:0046777 IDA:TAIR P protein autophosphorylation
GO:0051510 IGI:TAIR P regulation of unidimensional cell growth
GO:0009741 IGI:TAIR P response to brassinosteroid
GO:0009826 IGI:TAIR P unidimensional cell growth

Domain Information

InterPro Annotations

Accession Description
IPR013320 Concanavalin A-like lectin/glucanase domain
IPR024788 Malectin-like carbohydrate-binding domain
IPR000719 Protein kinase domain
IPR017441 Protein kinase, ATP binding site
IPR011009 Protein kinase-like domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR008271 Serine/threonine-protein kinase, active site

UniProt Annotations

Entry Information

Gene Name
receptor-like protein kinase THESEUS 1
Protein Entry
THE1_ARATH
UniProt ID
Q9LK35
Species
Arabidopsis

Comments

Comment Type Description
Disruption Phenotype No visible phenotype; due to redundancy with HERK1. Herk1 and the1 double mutants are stunted. In the1-4, shorter hypocotyls without brassinolide (BL) treatment. In the1-3, partially restored hypocotyl growth defect of prc1-8 and of other cellulose-deficient mutants. {ECO:0000269|PubMed:17540573, ECO:0000269|PubMed:19383785}.
Function Receptor-like protein kinase required for cell elongation during vegetative growth, mostly in a brassinosteroid- (BR-) independent manner. Mediates the response of growing plant cells to the perturbation of cellulose synthesis and may act as a cell-wall-integrity sensor. Controls ectopic-lignin accumulation in cellulose-deficient mutant backgrounds. {ECO:0000269|PubMed:17540573, ECO:0000269|PubMed:19383785}.
Induction By brassinosteroids (BR). {ECO:0000269|PubMed:19383785}.
Miscellaneous Semidominant suppressor of the cellulose-deficient mutant procuste1-1.
Miscellaneous This protein was called 'Theseus' after the Greek mythological figure Theseus, who slew the brigand Procustes.
Ptm Autophosphorylated.
Similarity Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
Similarity Contains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17540573, ECO:0000269|PubMed:17644812}; Single-pass type I membrane protein {ECO:0000269|PubMed:17540573, ECO:0000269|PubMed:17644812}.
Tissue Specificity Expressed in most vegetative tissues, including leaves, stems and roots, primarily in expanding cells and vascular tissue. {ECO:0000269|PubMed:17540573, ECO:0000269|PubMed:19383785}.
Web Resource Name=PlantP kinase Classification PPC; URL="http://plantsp.genomics.purdue.edu/family/class.html";

Identical and Related Proteins

Unique RefSeq proteins for LMP011240 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15239630 RefSeq NP_200249 855 receptor-like protein kinase THESEUS 1

Identical Sequences to LMP011240 proteins

Reference Database Accession Length Protein Name
GI:15239630 EMBL CAW43138.1 855 unnamed protein product [Arabidopsis thaliana]
GI:15239630 EMBL CBC08666.1 855 unnamed protein product [Arabidopsis thaliana]
GI:15239630 EMBL CBC00826.1 855 unnamed protein product [Arabidopsis thaliana]
GI:15239630 EMBL CBC05556.1 855 unnamed protein product [Arabidopsis thaliana]
GI:15239630 GenBank ADT59744.1 855 Sequence 378 from patent US 7847156
GI:15239630 gnl TAIR 855 receptor-like protein kinase THESEUS 1 [Arabidopsis thaliana]

Related Sequences to LMP011240 proteins

Reference Database Accession Length Protein Name
GI:15239630 GenBank EFH42299.1 852 hypothetical protein ARALYDRAFT_495518 [Arabidopsis lyrata subsp. lyrata]
GI:15239630 GenBank EOA12897.1 860 hypothetical protein CARUB_v10025871mg [Capsella rubella]
GI:15239630 RefSeq XP_002866040.1 852 hypothetical protein ARALYDRAFT_495518 [Arabidopsis lyrata subsp. lyrata]
GI:15239630 RefSeq XP_006279999.1 860 hypothetical protein CARUB_v10025871mg [Capsella rubella]
GI:15239630 RefSeq XP_010446855.1 855 PREDICTED: receptor-like protein kinase THESEUS 1 [Camelina sativa]
GI:15239630 RefSeq XP_010482846.1 855 PREDICTED: receptor-like protein kinase THESEUS 1 [Camelina sativa]