Gene/Proteome Database (LMPD)
LMPD ID
LMP011269
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
serine/threonine-protein kinase BRI1-like 1
Gene Symbol
Synonyms
BRI1 like; BRL1; F20N2.4
Alternate Names
serine/threonine-protein kinase BRI1-like 1
Chromosome
1
EC Number
2.7.11.1
Summary
mutant has Altered vascular cell differentiation; LRR Receptor Kinase
Orthologs
Proteins
| serine/threonine-protein kinase BRI1-like 1 | |
|---|---|
| Refseq ID | NP_001117501 |
| Protein GI | 186491196 |
| UniProt ID | Q9ZWC8 |
| mRNA ID | NM_001124029 |
| Length | 1166 |
| RefSeq Status | REVIEWED |
| MKQRWLLVLILCFFTTSLVMGIHGKHLINDDFNETALLLAFKQNSVKSDPNNVLGNWKYESGRGSCSWRGVSCSDDGRIVGLDLRNSGLTGTLNLVNLTALPNLQNLYLQGNYFSSGGDSSGSDCYLQVLDLSSNSISDYSMVDYVFSKCSNLVSVNISNNKLVGKLGFAPSSLQSLTTVDLSYNILSDKIPESFISDFPASLKYLDLTHNNLSGDFSDLSFGICGNLTFFSLSQNNLSGDKFPITLPNCKFLETLNISRNNLAGKIPNGEYWGSFQNLKQLSLAHNRLSGEIPPELSLLCKTLVILDLSGNTFSGELPSQFTACVWLQNLNLGNNYLSGDFLNTVVSKITGITYLYVAYNNISGSVPISLTNCSNLRVLDLSSNGFTGNVPSGFCSLQSSPVLEKILIANNYLSGTVPMELGKCKSLKTIDLSFNELTGPIPKEIWMLPNLSDLVMWANNLTGTIPEGVCVKGGNLETLILNNNLLTGSIPESISRCTNMIWISLSSNRLTGKIPSGIGNLSKLAILQLGNNSLSGNVPRQLGNCKSLIWLDLNSNNLTGDLPGELASQAGLVMPGSVSGKQFAFVRNEGGTDCRGAGGLVEFEGIRAERLERLPMVHSCPATRIYSGMTMYTFSANGSMIYFDISYNAVSGFIPPGYGNMGYLQVLNLGHNRITGTIPDSFGGLKAIGVLDLSHNNLQGYLPGSLGSLSFLSDLDVSNNNLTGPIPFGGQLTTFPVSRYANNSGLCGVPLRPCGSAPRRPITSRIHAKKQTVATAVIAGIAFSFMCFVMLVMALYRVRKVQKKEQKREKYIESLPTSGSCSWKLSSVPEPLSINVATFEKPLRKLTFAHLLEATNGFSAETMVGSGGFGEVYKAQLRDGSVVAIKKLIRITGQGDREFMAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWGSLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMKADTEEDESLDEFSLKETPLVEESRDKEP | |
Gene Information
Entrez Gene ID
Gene Name
serine/threonine-protein kinase BRI1-like 1
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0005886 | IDA:TAIR | C | plasma membrane |
| GO:0005524 | IEA:UniProtKB-KW | F | ATP binding |
| GO:0004674 | IEA:UniProtKB-KW | F | protein serine/threonine kinase activity |
| GO:0005496 | IEA:UniProtKB-KW | F | steroid binding |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR013320 | Concanavalin A-like lectin/glucanase domain |
| IPR001611 | Leucine-rich repeat |
| IPR013210 | Leucine-rich repeat-containing N-terminal, type 2 |
| IPR000719 | Protein kinase domain |
| IPR017441 | Protein kinase, ATP binding site |
| IPR011009 | Protein kinase-like domain |
| IPR008271 | Serine/threonine-protein kinase, active site |
UniProt Annotations
Entry Information
Gene Name
serine/threonine-protein kinase BRI1-like 1
Protein Entry
BRL1_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | ATP + a protein = ADP + a phosphoprotein. |
| Domain | A 70 amino acid island between the 19th and the 20th LRR is essential for the binding of brassinosteroids. {ECO:0000250}. |
| Domain | Contains two pairs of conservatively spaced Cys (Cys pair 1 and 2) possibly involved in forming some heterodimers. {ECO:0000250}. |
| Function | Receptor with a serine/threonine-protein kinase activity. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development. Binds brassinolide. May be involved in cell growth and vascular differentiation. {ECO:0000269|PubMed:15469497, ECO:0000269|PubMed:15486337}. |
| Interaction | Q94F62:BAK1; NbExp=5; IntAct=EBI-590903, EBI-617138; Q9FMZ0:BKI1; NbExp=4; IntAct=EBI-590903, EBI-1111615; |
| Similarity | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}. |
| Similarity | Contains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}. |
| Similarity | Contains 23 LRR (leucine-rich) repeats. {ECO:0000305}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:15486337}; Single-pass type I membrane protein {ECO:0000269|PubMed:15486337}. |
| Tissue Specificity | Predominantly expressed in vascular tissues. From 7 day old seedlings, it is expressed in the columella cells of the root tip, in the vascular initials in the meristematic region of the root and in vascular tissues. After germination, it is expressed in the stele cell and in the early differentiation zone of the root, where the expression continues from the root to the hypocotyls and cotyledons following the midvein. In mature plants, it is expressed in the vasculature of the leaf, predominantly in the midvein, and in the vascular bundles of inflorescence stems. Localizes to procambial cells of the vascular bundles located between the differentiating xylem and the phloem. {ECO:0000269|PubMed:15469497, ECO:0000269|PubMed:15486337}. |
| Web Resource | Name=PlantP kinase Classification PPC; URL="http://plantsp.genomics.purdue.edu/family/class.html"; |
Identical and Related Proteins
Unique RefSeq proteins for LMP011269 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 186491196 | RefSeq | NP_001117501 | 1166 | serine/threonine-protein kinase BRI1-like 1 |
Identical Sequences to LMP011269 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:186491196 | EMBL | CBD32326.1 | 1166 | unnamed protein product [Arabidopsis thaliana] |
| GI:186491196 | EMBL | CBD26007.1 | 1166 | unnamed protein product [Arabidopsis thaliana] |
| GI:186491196 | GenBank | ACN59256.1 | 1166 | leucine-rich repeat receptor-like protein kinase, partial [Arabidopsis thaliana] |
| GI:186491196 | GenBank | AEE33271.1 | 1166 | serine/threonine-protein kinase BRI1-like 1 [Arabidopsis thaliana] |
| GI:186491196 | GenBank | AEE33272.1 | 1166 | serine/threonine-protein kinase BRI1-like 1 [Arabidopsis thaliana] |
| GI:186491196 | SwissProt | Q9ZWC8.1 | 1166 | RecName: Full=Serine/threonine-protein kinase BRI1-like 1; AltName: Full=BRASSINOSTEROID INSENSITIVE 1-like protein 1; Flags: Precursor [Arabidopsis thaliana] |
Related Sequences to LMP011269 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:186491196 | GenBank | EFH70773.1 | 1173 | hypothetical protein ARALYDRAFT_892562 [Arabidopsis lyrata subsp. lyrata] |
| GI:186491196 | RefSeq | XP_002894514.1 | 1173 | hypothetical protein ARALYDRAFT_892562 [Arabidopsis lyrata subsp. lyrata] |
| GI:186491196 | RefSeq | XP_010501177.1 | 1169 | PREDICTED: serine/threonine-protein kinase BRI1-like 1 isoform X1 [Camelina sativa] |
| GI:186491196 | RefSeq | XP_010501178.1 | 1169 | PREDICTED: serine/threonine-protein kinase BRI1-like 1 isoform X2 [Camelina sativa] |
| GI:186491196 | RefSeq | XP_010462414.1 | 1169 | PREDICTED: serine/threonine-protein kinase BRI1-like 1 [Camelina sativa] |
| GI:186491196 | RefSeq | XP_010480102.1 | 1167 | PREDICTED: serine/threonine-protein kinase BRI1-like 1 [Camelina sativa] |