Gene/Proteome Database (LMPD)

LMPD ID
LMP011276
Gene ID
838804
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
serine/threonine-protein phosphatase BSU1
Gene Symbol
BSU1
Synonyms
BRI1 SUPPRESSOR 1; BSU1; F21B7.7
Alternate Names
serine/threonine-protein phosphatase BSU1
Chromosome
1
EC Number
3.1.3.16
Summary
encodes a serine threonine protein phosphatase with an N-terminal Kelch-repeat domain, which is nuclear localized and expressed preferentially in elongating cells. Genetic evidence suggest that this gene plays a redundant role (along with other members of the same gene family) in modulating growth in response to brassinosteroid.
Orthologs
View orthologs and multiple alignments for BSU1

Proteins

serine/threonine-protein phosphatase BSU1
Refseq ID NP_171844
Protein GI 240253996
UniProt ID Q9LR78
mRNA ID NM_100227
Length 793
RefSeq Status REVIEWED
MAPDQSYQYPSPSYESIQTFYDTDEDWPGPRCGHTLTAVFVNNSHQLILFGGSTTAVANHNSSLPEISLDGVTNSVHSFDVLTRKWTRLNPIGDVPSPRACHAAALYGTLILIQGGIGPSGPSDGDVYMLDMTNNKWIKFLVGGETPSPRYGHVMDIAAQRWLVIFSGNNGNEILDDTWALDTRGPFSWDRLNPSGNQPSGRMYASGSSREDGIFLLCGGIDHSGVTLGDTYGLKMDSDNVWTPVPAVAPSPRYQHTAVFGGSKLHVIGGILNRARLIDGEAVVAVLDTETGEWVDTNQPETSASGANRQNQYQLMRRCHHAAASFGSHLYVHGGIREDVLLDDLLVAETSQSSSPEPEEDNPDNYMLLDDYLMDEPKPLSSEPEASSFIMRSTSEIAMDRLAEAHNLPTIENAFYDSAIEGYVPLQHGAETVGNRGGLVRTASLDQSTQDLHKKVISTLLRPKTWTPPANRDFFLSYLEVKHLCDEVEKIFMNEPTLLQLKVPIKVFGDIHGQYGDLMRLFHEYGHPSVEGDITHIDYLFLGDYVDRGQHSLEIIMLLFALKIEYPKNIHLIRGNHESLAMNRIYGFLTECEERMGESYGFEAWLKINQVFDYLPLAALLEKKVLCVHGGIGRAVTIEEIENIERPAFPDTGSMVLKDILWSDPTMNDTVLGIVDNARGEGVVSFGPDIVKAFLERNGLEMILRAHECVIDGFERFADGRLITVFSATNYCGTAQNAGAILVIGRDMVIYPKLIHPHPPPISSSEEDYTDKAWMQELNIEMPPTPARGESSE

Gene Information

Entrez Gene ID
838804
Gene Name
serine/threonine-protein phosphatase BSU1
Gene Symbol
BSU1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005634 IDA:TAIR C nucleus
GO:0005506 IEA:InterPro F iron ion binding
GO:0030145 IEA:InterPro F manganese ion binding
GO:0004722 IDA:TAIR F protein serine/threonine phosphatase activity
GO:0009742 IGI:TAIR P brassinosteroid mediated signaling pathway
GO:0016311 IDA:GOC P dephosphorylation
GO:0032880 IDA:TAIR P regulation of protein localization

KEGG Pathway Links

KEGG Pathway ID Description
ath04075 Plant hormone signal transduction
ko04075 Plant hormone signal transduction

Domain Information

InterPro Annotations

Accession Description
IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR015916 Galactose oxidase, beta-propeller
IPR015915 Kelch-type beta propeller
IPR029052 Metallo-dependent phosphatase-like
IPR012391 Serine/threonine protein phosphatase, BSU1
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase

UniProt Annotations

Entry Information

Gene Name
serine/threonine-protein phosphatase BSU1
Protein Entry
BSU1_ARATH
UniProt ID
Q9LR78
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity [a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate. {ECO:0000269|PubMed:14977918}.
Cofactor Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Note=Binds 2 manganese ions per subunit. {ECO:0000250};
Enzyme Regulation Activated by phosphorylation at Ser-764 by CDG1. {ECO:0000269|PubMed:21855796}.
Function Phosphatase that acts as a positive regulator of brassinosteroid (BR) signaling (PubMed:14977918, PubMed:21855796). Dephosphorylates BES1, a transcription factor that regulates the expression of BR-response genes, thereby playing an important role in the regulation of response to BRs (PubMed:14977918). Inactivates the negative regulator of BR signaling ASK7/BIN2 by dephosphorylation at 'Tyr-200' (PubMed:21855796). {ECO:0000269|PubMed:14977918, ECO:0000269|PubMed:21855796}.
Ptm Phosphorylated at Ser-395 and Ser-444. Phosphorylated at Ser- 764 by CDG1 and CDL1. {ECO:0000269|PubMed:21855796}.
Sequence Caution Sequence=AAF86539.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the PPP phosphatase family. BSU subfamily. {ECO:0000305}.
Similarity Contains 5 Kelch repeats. {ECO:0000305}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14977918}.
Subunit Interacts with CDG1, CDL1 and ASK7/BIN2. {ECO:0000269|PubMed:21855796}.
Tissue Specificity Mainly expressed in young, elongating tissues. In young seedlings, it is expressed at the base of the hypocotyl, at the tip and most peripheral cell layers of cotyledons, and in the vascular cylinder of roots, particularly in the elongation zone and at the point of emergence of lateral roots. In mature plants, it is still present in the root vasculature, but almost completely absent in fully expanded stems and leaves. In flowers, it is mainly expressed in sepal veins, anther filaments, and in the style, suggesting that BSU1 is expressed in actively growing regions and apparently enriched in vascular tissues. {ECO:0000269|PubMed:14977918}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011276 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
240253996 RefSeq NP_171844 793 serine/threonine-protein phosphatase BSU1

Identical Sequences to LMP011276 proteins

Reference Database Accession Length Protein Name
GI:240253996 EMBL CAW80055.1 793 unnamed protein product [Arabidopsis thaliana]
GI:240253996 EMBL CBA12739.1 793 unnamed protein product [Arabidopsis thaliana]
GI:240253996 EMBL CBC78544.1 793 unnamed protein product [Arabidopsis thaliana]
GI:240253996 GenBank AAR19789.1 793 BSU1 Ser/Thr phosphatase [Arabidopsis thaliana]
GI:240253996 GenBank AEE27572.1 793 serine/threonine-protein phosphatase BSU1 [Arabidopsis thaliana]
GI:240253996 SwissProt Q9LR78.2 793 RecName: Full=Serine/threonine-protein phosphatase BSU1; AltName: Full=Bri1 suppressor protein 1 [Arabidopsis thaliana]

Related Sequences to LMP011276 proteins

Reference Database Accession Length Protein Name
GI:240253996 EMBL CAW80049.1 812 unnamed protein product [Arabidopsis thaliana]
GI:240253996 EMBL CBA12733.1 812 unnamed protein product [Arabidopsis thaliana]
GI:240253996 EMBL CBC78531.1 812 unnamed protein product [Arabidopsis thaliana]
GI:240253996 GenBank EFH68419.1 795 Serine/threonine-protein phosphatase BSU1 [Arabidopsis lyrata subsp. lyrata]
GI:240253996 RefSeq XP_002892160.1 795 Serine/threonine-protein phosphatase BSU1 [Arabidopsis lyrata subsp. lyrata]
GI:240253996 RefSeq XP_010474966.1 800 PREDICTED: serine/threonine-protein phosphatase BSU1-like [Camelina sativa]