Gene/Proteome Database (LMPD)

LMPD ID
LMP011293
Gene ID
840320
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
somatic embryogenesis receptor kinase 2
Gene Symbol
SERK2
Synonyms
ATSERK2; F23M19.11; F23M19_11; SERK2; somatic embryogenesis receptor-like kinase 2
Alternate Names
somatic embryogenesis receptor kinase 2
Chromosome
1
EC Number
2.7.11.1
Summary
Plasma membrane LRR receptor-like serine threonine kinase expressed during embryogenesis in locules until stage 6 anthers, with higher expression in the tapetal cell layer. SERK1 and SERK2 receptor kinases function redundantly as an important control point for sporophytic development controlling male gametophyte production.
Orthologs
View orthologs and multiple alignments for SERK2

Proteins

somatic embryogenesis receptor kinase 2
Refseq ID NP_174683
Protein GI 15218543
UniProt ID Q9XIC7
mRNA ID NM_103144
Length 628
RefSeq Status REVIEWED
MGRKKFEAFGFVCLISLLLLFNSLWLASSNMEGDALHSLRANLVDPNNVLQSWDPTLVNPCTWFHVTCNNENSVIRVDLGNADLSGQLVPQLGQLKNLQYLELYSNNITGPVPSDLGNLTNLVSLDLYLNSFTGPIPDSLGKLFKLRFLRLNNNSLTGPIPMSLTNIMTLQVLDLSNNRLSGSVPDNGSFSLFTPISFANNLDLCGPVTSRPCPGSPPFSPPPPFIPPPIVPTPGGYSATGAIAGGVAAGAALLFAAPALAFAWWRRRKPQEFFFDVPAEEDPEVHLGQLKRFSLRELQVATDSFSNKNILGRGGFGKVYKGRLADGTLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCLRERPPSQLPLAWSIRQQIALGSARGLSYLHDHCDPKIIHRDVKAANILLDEEFEAVVGDFGLARLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPDLQSNYTEAEVEQLIQVALLCTQSSPMERPKMSEVVRMLEGDGLAEKWDEWQKVEVLRQEVELSSHPTSDWILDSTDNLHAMELSGPR

Gene Information

Entrez Gene ID
840320
Gene Name
somatic embryogenesis receptor kinase 2
Gene Symbol
SERK2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IDA:UniProtKB C plasma membrane
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0008289 IEA:UniProtKB-KW F lipid binding
GO:0004674 IEA:UniProtKB-KW F protein serine/threonine kinase activity
GO:0033612 IPI:UniProtKB F receptor serine/threonine kinase binding
GO:0009742 IMP:TAIR P brassinosteroid mediated signaling pathway
GO:0009556 IMP:TAIR P microsporogenesis
GO:0010152 IMP:TAIR P pollen maturation

Domain Information

InterPro Annotations

Accession Description
IPR013320 Concanavalin A-like lectin/glucanase domain
IPR001611 Leucine-rich repeat
IPR013210 Leucine-rich repeat-containing N-terminal, type 2
IPR000719 Protein kinase domain
IPR017441 Protein kinase, ATP binding site
IPR011009 Protein kinase-like domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR008271 Serine/threonine-protein kinase, active site

UniProt Annotations

Entry Information

Gene Name
somatic embryogenesis receptor kinase 2
Protein Entry
SERK2_ARATH
UniProt ID
Q9XIC7
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + a protein = ADP + a phosphoprotein.
Disruption Phenotype No visible phenotype. Serk1 and serk2 double mutants are completely male sterile due to a failure in tapetum specification. {ECO:0000269|PubMed:16284305, ECO:0000269|PubMed:16284306}.
Function Serine/threonine-kinase involved in brassinosteroid- dependent and -independent signaling pathways. Acts redundantly with SERK1 as a control point for sporophytic development controlling male gametophyte production. {ECO:0000269|PubMed:18667726}.
Ptm Autophosphorylated. {ECO:0000269|PubMed:19105183}.
Similarity Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
Similarity Contains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}.
Similarity Contains 4 LRR (leucine-rich) repeats. {ECO:0000305}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16284305}; Single-pass type I membrane protein {ECO:0000269|PubMed:16284305}.
Subunit Homo- and heterodimer. Component of the SERK1 signaling complex, composed of KAPP, CDC48A, GRF6 or GRF7, SERK1, SERK2, SERK3/BAK1 and BRI1 (By similarity). Interacts with the EF-Tu receptor EFR and FLS2 in a specific ligand-induced manner. {ECO:0000250, ECO:0000269|PubMed:16284305, ECO:0000269|PubMed:21693696}.
Tissue Specificity Expressed in flowers, tapetum, developing microspores, all cells of the embryo sac, provascular strands and developing vascular bundles. Low expression in adult vascular tissue. {ECO:0000269|PubMed:16284305}.
Web Resource Name=PlantP kinase Classification PPC; URL="http://plantsp.genomics.purdue.edu/family/class.html";

Identical and Related Proteins

Unique RefSeq proteins for LMP011293 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15218543 RefSeq NP_174683 628 somatic embryogenesis receptor kinase 2

Identical Sequences to LMP011293 proteins

Reference Database Accession Length Protein Name
GI:15218543 EMBL CBD14094.1 628 unnamed protein product [Arabidopsis thaliana]
GI:15218543 GenBank ACX04473.1 628 Sequence 27311 from patent US 7569389
GI:15218543 GenBank ADM02574.1 628 Sequence 47 from patent US 7723566
GI:15218543 GenBank ADT45274.1 628 Sequence 55 from patent US 7838728
GI:15218543 GenBank AEE31686.1 628 somatic embryogenesis receptor kinase 2 [Arabidopsis thaliana]
GI:15218543 GenBank AEH74991.1 628 Sequence 21 from patent US 7956240

Related Sequences to LMP011293 proteins

Reference Database Accession Length Protein Name
GI:15218543 EMBL CAX06440.1 628 unnamed protein product [Arabidopsis thaliana]
GI:15218543 EMBL CBA12778.1 628 unnamed protein product [Arabidopsis thaliana]
GI:15218543 EMBL CBD14171.1 628 unnamed protein product [Arabidopsis thaliana]
GI:15218543 GenBank AAK68073.1 628 somatic embryogenesis receptor-like kinase 2 [Arabidopsis thaliana]
GI:15218543 GenBank ADM02564.1 628 Sequence 30 from patent US 7723566
GI:15218543 GenBank AHL57127.1 628 Sequence 18 from patent US 8642837