Gene/Proteome Database (LMPD)

LMPD ID
LMP011294
Gene ID
815862
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
somatic embryogenesis receptor kinase 4
Gene Symbol
SERK4
Synonyms
AT2G13780; ATSERK4; BAK1-LIKE 1; BAK7; BKK1; BRI1- ASSOCIATED KINASE 7; F13J11.14; F13J11_14; SERK4; somatic embryogenesis receptor-like kinase 4; SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE 4
Alternate Names
somatic embryogenesis receptor kinase 4
Chromosome
2
EC Number
2.7.10.1

Proteins

somatic embryogenesis receptor kinase 4
Refseq ID NP_178999
Protein GI 30678986
UniProt ID Q9SKG5
mRNA ID NM_126955
Length 620
RefSeq Status REVIEWED
MTSSKMEQRSLLCFLYLLLLFNFTLRVAGNAEGDALTQLKNSLSSGDPANNVLQSWDATLVTPCTWFHVTCNPENKVTRVDLGNAKLSGKLVPELGQLLNLQYLELYSNNITGEIPEELGDLVELVSLDLYANSISGPIPSSLGKLGKLRFLRLNNNSLSGEIPMTLTSVQLQVLDISNNRLSGDIPVNGSFSLFTPISFANNSLTDLPEPPPTSTSPTPPPPSGGQMTAAIAGGVAAGAALLFAVPAIAFAWWLRRKPQDHFFDVPAEEDPEVHLGQLKRFTLRELLVATDNFSNKNVLGRGGFGKVYKGRLADGNLVAVKRLKEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCLRERPEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHRDVKAANILLDEEFEAVVGDFGLAKLMNYNDSHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVMLLELITGQKAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQLIQMALLCTQSSAMERPKMSEVVRMLEGDGLAERWEEWQKEEMPIHDFNYQAYPHAGTDWLIPYSNSLIENDYPSGPR

Gene Information

Entrez Gene ID
815862
Gene Name
somatic embryogenesis receptor kinase 4
Gene Symbol
SERK4
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IDA:UniProtKB C plasma membrane
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0033612 IPI:UniProtKB F receptor serine/threonine kinase binding
GO:0004675 ISS:TAIR F transmembrane receptor protein serine/threonine kinase activity
GO:0004714 IEA:UniProtKB-EC F transmembrane receptor protein tyrosine kinase activity
GO:0009742 IGI:TAIR P brassinosteroid mediated signaling pathway
GO:0008219 IGI:TAIR P cell death
GO:0010150 IGI:TAIR P leaf senescence
GO:0060548 IMP:UniProtKB P negative regulation of cell death
GO:0006468 ISS:TAIR P protein phosphorylation
GO:1900140 IMP:UniProtKB P regulation of seedling development
GO:0010200 IEP:TAIR P response to chitin
GO:0007178 ISS:GOC P transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG Pathway Links

KEGG Pathway ID Description
ath04626 Plant-pathogen interaction
ko04626 Plant-pathogen interaction

Domain Information

InterPro Annotations

Accession Description
IPR013320 Concanavalin A-like lectin/glucanase domain
IPR001611 Leucine-rich repeat
IPR013210 Leucine-rich repeat-containing N-terminal, type 2
IPR000719 Protein kinase domain
IPR017441 Protein kinase, ATP binding site
IPR011009 Protein kinase-like domain
IPR008271 Serine/threonine-protein kinase, active site

UniProt Annotations

Entry Information

Gene Name
somatic embryogenesis receptor kinase 4
Protein Entry
SERK4_ARATH
UniProt ID
Q9SKG5
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. {ECO:0000255|PROSITE- ProRule:PRU10027}.
Catalytic Activity ATP + a protein = ADP + a phosphoprotein.
Disruption Phenotype No visible phenotype; due to the redundancy with BAK1. Bak1 and bkk1 double mutants are seedling lethal. {ECO:0000269|PubMed:17600708, ECO:0000269|PubMed:18667726}.
Function Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Positively regulates the BR- dependent plant growth pathway and negatively regulates the BR- independent cell-death pathway. {ECO:0000269|PubMed:17600708, ECO:0000269|PubMed:18667726, ECO:0000269|PubMed:19124768}.
Ptm Autophosphorylated on Thr and Tyr residues. {ECO:0000269|PubMed:19105183}.
Sequence Caution Sequence=AAD28318.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAE98698.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};
Similarity Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
Similarity Contains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}.
Similarity Contains 5 LRR (leucine-rich) repeats. {ECO:0000305}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Subunit Interacts with the EF-Tu receptor EFR and FLS2 in a specific ligand-induced manner. {ECO:0000269|PubMed:21693696}.
Web Resource Name=PlantP kinase Classification PPC; URL="http://plantsp.genomics.purdue.edu/family/class.html";

Identical and Related Proteins

Unique RefSeq proteins for LMP011294 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
30678986 RefSeq NP_178999 620 somatic embryogenesis receptor kinase 4

Identical Sequences to LMP011294 proteins

Reference Database Accession Length Protein Name
GI:30678986 EMBL CBA12745.1 620 unnamed protein product [Arabidopsis thaliana]
GI:30678986 EMBL CBD14100.1 620 unnamed protein product [Arabidopsis thaliana]
GI:30678986 GenBank ADT59812.1 620 Sequence 514 from patent US 7847156
GI:30678986 GenBank AEC06259.1 620 somatic embryogenesis receptor kinase 4 [Arabidopsis thaliana]
GI:30678986 GenBank AEH74994.1 620 Sequence 27 from patent US 7956240
GI:30678986 SwissProt Q9SKG5.2 620 RecName: Full=Somatic embryogenesis receptor kinase 4; Short=AtSERK4; AltName: Full=Protein BAK1-like 1; Short=AtBKK1; AltName: Full=Somatic embryogenesis receptor-like kinase 2; Flags: Precursor [Arabidopsis thaliana]

Related Sequences to LMP011294 proteins

Reference Database Accession Length Protein Name
GI:30678986 EMBL CAC38731.1 596 unnamed protein product [Arabidopsis thaliana]
GI:30678986 EMBL CAF33250.1 615 unnamed protein product [Arabidopsis thaliana]
GI:30678986 GenBank EFH60068.1 620 hypothetical protein ARALYDRAFT_899604 [Arabidopsis lyrata subsp. lyrata]
GI:30678986 GenBank ADT45278.1 615 Sequence 63 from patent US 7838728
GI:30678986 GenBank AHL57131.1 616 Sequence 26 from patent US 8642837
GI:30678986 RefSeq XP_002883809.1 620 hypothetical protein ARALYDRAFT_899604 [Arabidopsis lyrata subsp. lyrata]