Gene/Proteome Database (LMPD)

LMPD ID
LMP011407
Gene ID
830283
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
triacylglycerol lipase SDP1
Gene Symbol
SDP1
Synonyms
F8F6.250; F8F6_250; SDP1; SUGAR-DEPENDENT1
Alternate Names
triacylglycerol lipase SDP1
Chromosome
5
EC Number
3.1.1.3

Proteins

triacylglycerol lipase SDP1
Refseq ID NP_196024
Protein GI 15237603
UniProt ID Q9LZA6
mRNA ID NM_120486
Length 825
RefSeq Status REVIEWED
MDISNEASVDPFSIGPSSIMGRTIAFRVLFCRSMSQLRRDLFRFLLHWFLRFKLTVSPFVSWFHPRNPQGILAVVTIIAFVLKRYTNVKIKAEMAYRRKFWRNMMRTALTYEEWAHAAKMLEKETPKMNESDLYDEELVKNKLQELRHRRQEGSLRDIMFCMRADLVRNLGNMCNSELHKGRLQVPRHIKEYIDEVSTQLRMVCNSDSEELSLEEKLSFMHETRHAFGRTALLLSGGASLGAFHVGVVRTLVEHKLLPRIIAGSSVGSIICAVVASRSWPELQSFFENSLHSLQFFDQLGGVFSIVKRVMTQGALHDIRQLQCMLRNLTSNLTFQEAYDMTGRILGITVCSPRKHEPPRCLNYLTSPHVVIWSAVTASCAFPGLFEAQELMAKDRSGEIVPYHPPFNLDPEVGTKSSSGRRWRDGSLEVDLPMMQLKELFNVNHFIVSQANPHIAPLLRLKDLVRAYGGRFAAKLAHLVEMEVKHRCNQVLELGFPLGGLAKLFAQEWEGDVTVVMPATLAQYSKIIQNPTHVELQKAANQGRRCTWEKLSAIKSNCGIELALDDSVAILNHMRRLKKSAERAATATSSSHHGLASTTRFNASRRIPSWNVLARENSTGSLDDLVTDNNLHASSGRNLSDSETESVELSSWTRTGGPLMRTASANKFIDFVQSLDIDIALVRGFSSSPNSPAVPPGGSFTPSPRSIAAHSDIESNSNSNNLGTSTSSITVTEGDLLQPERTSNGFVLNVVKRENLGMPSIGNQNTELPESVQLDIPEKEMDCSSVSEHEEDDNDNEEEHNGSSLVTVSSEDSGLQEPVSGSVIDA

Gene Information

Entrez Gene ID
830283
Gene Name
triacylglycerol lipase SDP1
Gene Symbol
SDP1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0012511 IDA:TAIR C monolayer-surrounded lipid storage body
GO:0004806 IDA:TAIR F triglyceride lipase activity
GO:0006071 IEA:UniProtKB-KW P glycerol metabolic process
GO:0019433 IMP:TAIR P triglyceride catabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00592 alpha-Linolenic acid metabolism
ath00590 Arachidonic acid metabolism
ath00565 Ether lipid metabolism
ath00591 Linoleic acid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase
IPR002641 Patatin/Phospholipase A2-related
IPR021771 Triacylglycerol lipase

UniProt Annotations

Entry Information

Gene Name
triacylglycerol lipase SDP1
Protein Entry
SDP1_ARATH
UniProt ID
Q9LZA6
Species
Arabidopsis

Comments

Comment Type Description
Biophysicochemical Properties pH dependence: Broad optimum pH around 8.0.;
Catalytic Activity Triacylglycerol + H(2)O = diacylglycerol + a carboxylate. {ECO:0000269|PubMed:16473965}.
Developmental Stage Transcript levels increase at the beginning of seed maturation and remain high until seed desiccation is completed. High levels early in seed imbibition, but decline as the seed germinates. {ECO:0000269|PubMed:16473965}.
Disruption Phenotype Not impaired in germination, but much slower rate of postgerminative growth. {ECO:0000269|PubMed:16473965}.
Enzyme Regulation Inhibited by diethyl-p-nitrophenyl phosphate, diisopropyl fluorophosphate and [E]-6-[bromoethylene]-3-[1- naphthalenyl]-2H-tetrahydropyran-2-one. {ECO:0000269|PubMed:16473965}.
Function Involved it the release of fatty acids from the oil body in germinating seedlings. Could hydrolyze triacylglycerols and diacylglycerols but not monoacylglycerols, phospholipids, galactolipids or cholesterol esters. {ECO:0000269|PubMed:16473965, ECO:0000269|PubMed:19136267}.
Miscellaneous Transcript levels do not correlate positively with enzyme activity, suggesting a post-transcriptional regulation.
Sequence Caution Sequence=BAD94338.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Similarity Contains 1 patatin domain. {ECO:0000305}.
Subcellular Location Lipid droplet {ECO:0000269|PubMed:16473965}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Associates with the oil body membrane.

Identical and Related Proteins

Unique RefSeq proteins for LMP011407 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15237603 RefSeq NP_196024 825 triacylglycerol lipase SDP1

Identical Sequences to LMP011407 proteins

Reference Database Accession Length Protein Name
GI:15237603 EMBL CAB85524.1 825 putative protein [Arabidopsis thaliana]
GI:15237603 GenBank AAM97135.1 825 putative protein [Arabidopsis thaliana]
GI:15237603 GenBank AFL30886.1 825 Sequence 556 from patent US 8168857
GI:15237603 GenBank AFO01132.1 825 Sequence 3 from patent US 8093452
GI:15237603 gnl TAIR 825 triacylglycerol lipase SDP1 [Arabidopsis thaliana]
GI:15237603 SwissProt Q9LZA6.1 825 RecName: Full=Triacylglycerol lipase SDP1; AltName: Full=Protein SUGAR-DEPENDENT 1 [Arabidopsis thaliana]

Related Sequences to LMP011407 proteins

Reference Database Accession Length Protein Name
GI:15237603 GenBank EFH47327.1 824 sugar-dependent1 [Arabidopsis lyrata subsp. lyrata]
GI:15237603 GenBank AFO01135.1 825 Sequence 8 from patent US 8093452
GI:15237603 GenBank AFO01136.1 825 Sequence 9 from patent US 8093452
GI:15237603 GenBank AFO01137.1 825 Sequence 10 from patent US 8093452
GI:15237603 RefSeq XP_002871068.1 824 sugar-dependent1 [Arabidopsis lyrata subsp. lyrata]
GI:15237603 RefSeq XP_006287072.1 828 hypothetical protein CARUB_v10000230mg [Capsella rubella]