Gene/Proteome Database (LMPD)
LMPD ID
LMP011426
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
sinapic acid:UDP-glucose glucosyltransferase
Gene Symbol
Synonyms
MIL23.13; UGT84A2
Alternate Names
sinapic acid:UDP-glucose glucosyltransferase
Chromosome
3
EC Number
2.4.1.-
Summary
Encodes a protein with sinapic acid:UDP-glucose glucosyltransferase activity. Mutants defective in this gene are hyper-fluorescent (which accumulate in their trichomes a compound that is likely to be 3',5'-dimethoxynaringenin chalcone or sinapoyltriacetic acid lactone, potential products of the concerted action of 4-coumarate CoA ligase and chalcone synthase on sinapic acid).
Orthologs
Proteins
| sinapic acid:UDP-glucose glucosyltransferase | |
|---|---|
| Refseq ID | NP_188793 |
| Protein GI | 15233091 |
| UniProt ID | Q9LVF0 |
| mRNA ID | NM_113051 |
| Length | 496 |
| RefSeq Status | REVIEWED |
| MELESSPPLPPHVMLVSFPGQGHVNPLLRLGKLLASKGLLITFVTTESWGKKMRISNKIQDRVLKPVGKGYLRYDFFDDGLPEDDEASRTNLTILRPHLELVGKREIKNLVKRYKEVTKQPVTCLINNPFVSWVCDVAEDLQIPCAVLWVQSCACLAAYYYYHHNLVDFPTKTEPEIDVQISGMPLLKHDEIPSFIHPSSPHSALREVIIDQIKRLHKTFSIFIDTFNSLEKDIIDHMSTLSLPGVIRPLGPLYKMAKTVAYDVVKVNISEPTDPCMEWLDSQPVSSVVYISFGTVAYLKQEQIDEIAYGVLNADVTFLWVIRQQELGFNKEKHVLPEEVKGKGKIVEWCSQEKVLSHPSVACFVTHCGWNSTMEAVSSGVPTVCFPQWGDQVTDAVYMIDVWKTGVRLSRGEAEERLVPREEVAERLREVTKGEKAIELKKNALKWKEEAEAAVARGGSSDRNLEKFVEKLGAKPVGKVQNGSHNHVLAGSIKSF | |
Gene Information
Entrez Gene ID
Gene Name
sinapic acid:UDP-glucose glucosyltransferase
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005737 | IDA:TAIR | C | cytoplasm |
| GO:0050284 | IDA:TAIR | F | sinapate 1-glucosyltransferase activity |
| GO:0009718 | IMP:TAIR | P | anthocyanin-containing compound biosynthetic process |
| GO:0009801 | IMP:TAIR | P | cinnamic acid ester metabolic process |
| GO:0080167 | IEP:TAIR | P | response to karrikin |
| GO:0009636 | IEA:UniProtKB-KW | P | response to toxic substance |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ath00940 | Phenylpropanoid biosynthesis |
| ko00940 | Phenylpropanoid biosynthesis |
BIOCYC Pathway Links
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR002213 | UDP-glucuronosyl/UDP-glucosyltransferase |
UniProt Annotations
Entry Information
Gene Name
sinapic acid:UDP-glucose glucosyltransferase
Protein Entry
U84A2_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Biophysicochemical Properties | Kinetic parameters: KM=250 uM for sinapate {ECO:0000269|PubMed:11042211}; |
| Catalytic Activity | UDP-glucose + sinapate = UDP + 1-sinapoyl-D- glucose. |
| Disruption Phenotype | No visible phenotype under normal growth condition, but reduced epidermal fluorescence due to reduced content of sinapoylmalate and hyper-fluorescence of trichomes due to accumulation of sinapic acid-derived polyketide. {ECO:0000269|PubMed:17217457}. |
| Function | Sinapate glucosyltransferase (SGT) required for the biosynthesis of the glucose ester sinapoylglucose and subsequently sinapoylmalate and sinapoylcholine. Is the major SGT activity in plant. Can glucosylate the phytotoxic xenobiotic compound 2,4,5- trichlorophenol (TCP). {ECO:0000269|PubMed:11042211, ECO:0000269|PubMed:11187886, ECO:0000269|PubMed:12721858, ECO:0000269|PubMed:17217457}. |
| Similarity | Belongs to the UDP-glycosyltransferase family. {ECO:0000305}. |
| Tissue Specificity | Expressed in roots, cotyledons, leaf veins and trichomes. {ECO:0000269|PubMed:17217457}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP011426 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 15233091 | RefSeq | NP_188793 | 496 | sinapic acid:UDP-glucose glucosyltransferase |
Identical Sequences to LMP011426 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15233091 | GenBank | AAN13000.1 | 496 | putative UDP-glucose:indole-3-acetate beta-D-glucosyltransferase [Arabidopsis thaliana] |
| GI:15233091 | GenBank | ACC18940.1 | 496 | Sequence 5 from patent US 7335814 |
| GI:15233091 | GenBank | ACW94348.1 | 496 | Sequence 13527 from patent US 7569389 |
| GI:15233091 | GenBank | AEE76523.1 | 496 | sinapic acid:UDP-glucose glucosyltransferase [Arabidopsis thaliana] |
| GI:15233091 | GenBank | AHL38758.1 | 496 | glycosyltransferase, partial [Arabidopsis thaliana] |
| GI:15233091 | SwissProt | Q9LVF0.1 | 496 | RecName: Full=UDP-glycosyltransferase 84A2; AltName: Full=Sinapate 1-glucosyltransferase 1; Short=AtSGT1 [Arabidopsis thaliana] |
Related Sequences to LMP011426 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:15233091 | GenBank | AAM13998.1 | 496 | putative UDP-glucose:indole-3-acetate beta-D-glucosyltransferase [Arabidopsis thaliana] |
| GI:15233091 | GenBank | ACW94349.1 | 483 | Sequence 13528 from patent US 7569389 |
| GI:15233091 | RefSeq | XP_010510360.1 | 496 | PREDICTED: UDP-glycosyltransferase 84A2-like [Camelina sativa] |
| GI:15233091 | RefSeq | XP_010466403.1 | 496 | PREDICTED: UDP-glycosyltransferase 84A2-like isoform X1 [Camelina sativa] |
| GI:15233091 | RefSeq | XP_010466404.1 | 496 | PREDICTED: UDP-glycosyltransferase 84A2-like isoform X2 [Camelina sativa] |
| GI:15233091 | RefSeq | XP_010488169.1 | 500 | PREDICTED: UDP-glycosyltransferase 84A2 [Camelina sativa] |