Gene/Proteome Database (LMPD)

LMPD ID
LMP011469
Gene ID
30314
Species
Danio rerio (Zebrafish)
Gene Name
apolipoprotein Eb
Gene Symbol
apoeb
Synonyms
apoe; cb82; fa96d02; hm:zeh1311; wu:fa03d06; wu:fa96d02; wu:fa97a11; wu:fc95h12; wu:fj54e06
Alternate Names
apolipoprotein Eb; ApoE-2; apo-Eb; zeh1311
Chromosome
16

Proteins

apolipoprotein Eb precursor
Refseq ID NP_571173
Protein GI 18858283
UniProt ID O42364
mRNA ID NM_131098
Length 281
RefSeq Status PROVISIONAL
MRSLVVFFALAVLTGCQARSLFQADAPQPRWEEMVDRFWQYVSELNTQTDGMVQNIKGSQLSRELDTLITDTMAELSSYSENLQTQMTPYASDAAGQLSKDLQLLAGKLQTDMTDAKERSTQYLQELKTMMEQNADDVKNRVGTYTRKLKKRLNKDTEEIRNTVATYMSEMQSRASQNADAVKDRFQPYMSQAQDGATQKLGAISELMKAQAQEVSEQLEVQAGALKEKLEETAENLRTSLEGRVDELTSLLAPYSQKIREQLQEVMDKIKEATAALPTQA

Gene Information

Entrez Gene ID
30314
Gene Name
apolipoprotein Eb
Gene Symbol
apoeb
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0008289 IEA:InterPro F lipid binding
GO:0006869 IEA:UniProtKB-KW P lipid transport
GO:0042157 IEA:InterPro P lipoprotein metabolic process

REACTOME Pathway Links

REACTOME Pathway ID Description
6176886 Binding and Uptake of Ligands by Scavenger Receptors
6176219 Chylomicron-mediated lipid transport
6176177 Lipoprotein metabolism
6176889 Scavenging by Class A Receptors

Domain Information

InterPro Annotations

Accession Description
IPR000074 Apolipoprotein A/E

UniProt Annotations

Entry Information

Gene Name
apolipoprotein Eb
Protein Entry
APOEB_DANRE
UniProt ID
O42364
Species
Zebrafish

Comments

Comment Type Description
Developmental Stage Highly expressed in the yolk syncytial layer during embryonic (starting at the blastula stage) and early larval development, an extraembryonic structure implicated in embryonic and larval nutrition. Also observed in the deep cell layer during blastula stage, in numerous ectodermal derivatives after gastrulation, and after 3 days of development in a limited number of cells both in brain and in the eyes.
Function Associated with several classes of plasma lipoproteins, it mediates uptake of lipoproteins through its ability to interact with specific cell surface receptors.
Similarity Belongs to the apolipoprotein A1/A4/E family. {ECO:0000305}.
Subcellular Location Secreted.

Identical and Related Proteins

Unique RefSeq proteins for LMP011469 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18858283 RefSeq NP_571173 281 apolipoprotein Eb precursor

Identical Sequences to LMP011469 proteins

Reference Database Accession Length Protein Name
GI:18858283 EMBL CAA74003.1 281 apolipoprotein E precursor protein [Danio rerio]
GI:18858283 EMBL CAB64946.1 281 apolipoprotein E precursor protein [Danio rerio]
GI:18858283 GenBank AAH65592.1 281 Apolipoprotein Eb [Danio rerio]
GI:18858283 RefSeq XP_005158143.1 281 PREDICTED: apolipoprotein Eb isoform X1 [Danio rerio]
GI:18858283 SwissProt O42364.1 281 RecName: Full=Apolipoprotein Eb; Short=Apo-Eb; Flags: Precursor [Danio rerio]

Related Sequences to LMP011469 proteins

Reference Database Accession Length Protein Name
GI:18858283 GenBank AAI54035.1 281 Apoeb protein [Danio rerio]
GI:18858283 GenBank ACI15893.1 281 apolipoprotein E-2 [Hemibarbus mylodon]
GI:18858283 GenBank AEX91932.1 281 apolipoprotein E [Carassius auratus x Cyprinus carpio]
GI:18858283 GenBank AEX91934.1 281 apolipoprotein E [Cyprinus carpio]
GI:18858283 GenBank AFI92850.1 281 apolipoprotein E [Cyprinus carpio]
GI:18858283 GenBank AFI92851.1 281 apolipoprotein E [Cyprinus carpio]