Gene/Proteome Database (LMPD)

LMPD ID
LMP011545
Gene ID
322857
Species
Danio rerio (Zebrafish)
Gene Name
prominin 1a
Gene Symbol
prom1a
Synonyms
prom1; proml1; fb75c01; wu:fb75c01
Alternate Names
prominin-1-A; prominin-1a.s11; prominin-1a.s18; prominin-1a.s19; prominin-1a.s20; prominin-like 1; prominin-like protein 1
Chromosome
14

Proteins

prominin-1-A precursor
Refseq ID NP_001108615
Protein GI 227430360
UniProt ID Q9W735
mRNA ID NM_001115143
Length 826
RefSeq Status PROVISIONAL
MLWKTALIFLCWGLTSGELQNGLSATPAAPARRTLDFGFVPSGVYDTVAYYEPGAIGILFNMMHAFLFVVQPNPFPEDLVISAAKDKFGAIQSEYQKVIYYELGFVVCAALGLLFTVLLPLVGLLFCLCRCCDNCGGEMHQRQRKNADCLRGLLTTLLLTTTFIITAGVLCAYAANQNLSSQLKGMRRLVKSNLKDLHTFANQTPAQIDYLISRYGTVKEQVLHDLENVGVILGGRIHEELGKEVKPALDATLSMTGTMRDTKDALENVSLTLETLQEGTVKLQANLSVVRNSLRNALNDPVCVDAPAPEICRNIRNSIPKLEIAANYSSLPDVTDQLNKVNDVLKTDLSQIVAKGIASFNDTPAMVTAQTRNIVEGVKVLLDDIGNNITSFSKMLPVHSSLANFTRMISHTHSQIEDIYPQIDQMDFYRWIGCITLCCMIVLILTFNFLGLLCGILGFDRHASPTTRGCVSNTGGNFLMAGVGFSFLFSWVLMGVITALFLAGGNLEKLVCEPFQTRQLFKVLDTPYLVNSAWRNFIPGYLYNDPEMDLTAYSLYSNCKDNRGIYSALHLDRIFNISSFFNTSVYSKDVSRKFEGLKVDLRGIILLESEGKVNLNNFSETGINEIDFAAYLEEVNKGVTRIDLIDFANQLDAQADQLSKGTLQTSLKGHANTIRQIHIQQVVPLEQSMSTLNQSIRLLERTSSDLPLRVEDVLKAVDDAQNLISYNATFVINQETEKYKQNIIGYFKQYIDWIRTSLALEVATCKPLSNIVDTVEILGCGFLLDSMNTFWFGLGCCTLFLLPSIILSVKLAKFYRRMDTEDVYDE

Gene Information

Entrez Gene ID
322857
Gene Name
prominin 1a
Gene Symbol
prom1a
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0042995 IEA:UniProtKB-KW C cell projection
GO:0005783 ISS:UniProtKB C endoplasmic reticulum
GO:0005793 ISS:UniProtKB C endoplasmic reticulum-Golgi intermediate compartment
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 ISS:UniProtKB C plasma membrane

Domain Information

InterPro Annotations

Accession Description
IPR008795 Prominin

UniProt Annotations

Entry Information

Gene Name
prominin 1a
Protein Entry
PRM1A_DANRE
UniProt ID
Q9W735
Species
Zebrafish

Comments

Comment Type Description
Function May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. Involved in regulation of MAPK and Akt signaling pathways (By similarity). {ECO:0000250}.
Similarity Belongs to the prominin family. {ECO:0000305}.
Subcellular Location Apical cell membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Cell projection, microvillus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011545 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
227430360 RefSeq NP_001108615 826 prominin-1-A precursor

Identical Sequences to LMP011545 proteins

Reference Database Accession Length Protein Name
GI:227430360 GenBank AAI63446.1 826 Prom1a protein [Danio rerio]
GI:227430360 SwissProt Q9W735.2 826 RecName: Full=Prominin-1-A; AltName: Full=Prominin-like protein 1 [Danio rerio]

Related Sequences to LMP011545 proteins

Reference Database Accession Length Protein Name
GI:227430360 GenBank ADY04840.1 856 prominin-1a.s20 splice variant [Danio rerio]
GI:227430360 RefSeq XP_005157404.1 856 PREDICTED: prominin-1-A isoform X7 [Danio rerio]
GI:227430360 RefSeq XP_005157406.1 849 PREDICTED: prominin-1-A isoform X9 [Danio rerio]
GI:227430360 RefSeq XP_005157408.1 841 PREDICTED: prominin-1-A isoform X10 [Danio rerio]
GI:227430360 RefSeq XP_009289543.1 888 PREDICTED: prominin-1-A isoform X2 [Danio rerio]
GI:227430360 RefSeq XP_009289544.1 879 PREDICTED: prominin-1-A isoform X3 [Danio rerio]