Gene/Proteome Database (LMPD)

LMPD ID
LMP011623
Gene ID
368415
Species
Danio rerio (Zebrafish)
Gene Name
phosphatase and tensin homolog B
Gene Symbol
ptenb
Synonyms
pten; fa11a08; fb73f10; fc83f12; fd16b10; fk90e11; wu:fa11a08; wu:fb73f10; wu:fc83f12; wu:fd16b10; wu:fk90e11; si:bz1g13.4
Chromosome
12

Proteins

phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Refseq ID NP_001001822
Protein GI 49227345
UniProt ID Q7ZZ56
mRNA ID NM_001001822
Length 399
RefSeq Status PROVISIONAL
MAAIIKEFVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKDHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDKWLSENDNHVAAIHCKAGKGRTGVMICAYLLHRGKFKKAQEALDFYDEVRTRDKKGVTIPSQRRYVYYYSYLLRNKLEYKPVALLFHKMVFETVPMFSGGTCNPQFVVYQLKVKIHTSNPAHTRREEKYMFFEFPQPLPVCGDIKVEFFHKQNKMMKKEKMFHFWVNTFFIPGSEESTEKVENGGLVKDLDGIQTAERGENDKDYLILTLSKTDLDKANKDKANRYFSPNFKVKMFFTKTVEEPSNSEASTSTSVTPDVSDNEPDHYRYSDTTDSDPENEQYDEEQITKV

Gene Information

Entrez Gene ID
368415
Gene Name
phosphatase and tensin homolog B
Gene Symbol
ptenb
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0000287 IEA:InterPro F magnesium ion binding
GO:0016314 IEA:InterPro F phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO:0051800 IEA:InterPro F phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
GO:0004725 IEA:InterPro F protein tyrosine phosphatase activity
GO:0008138 IEA:InterPro F protein tyrosine/serine/threonine phosphatase activity
GO:0046855 IEA:InterPro P inositol phosphate dephosphorylation
GO:0030336 IEA:InterPro P negative regulation of cell migration
GO:0008285 IEA:InterPro P negative regulation of cell proliferation
GO:0051895 IEA:InterPro P negative regulation of focal adhesion assembly
GO:0051898 IEA:InterPro P negative regulation of protein kinase B signaling
GO:0046856 IEA:InterPro P phosphatidylinositol dephosphorylation
GO:0031647 IEA:InterPro P regulation of protein stability

Domain Information

InterPro Annotations

Accession Description
IPR017361 Bifunctional phosphatidylinositol trisphosphate phosphatase/dual specificity phosphatase PTEN
IPR000008 C2 domain
IPR000340 Dual specificity phosphatase, catalytic domain
IPR016130 Protein-tyrosine phosphatase, active site
IPR029021 Protein-tyrosine phosphatase-like
IPR014020 Tensin phosphatase, C2 domain
IPR029023 Tensin phosphatase, lipid phosphatase domain

UniProt Annotations

Entry Information

Gene Name
phosphatase and tensin homolog B
Protein Entry
Q7ZZ56_DANRE
UniProt ID
Q7ZZ56
Species
Zebrafish

Identical and Related Proteins

Unique RefSeq proteins for LMP011623 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
49227345 RefSeq NP_001001822 399 phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

Identical Sequences to LMP011623 proteins

Reference Database Accession Length Protein Name
GI:49227345 GenBank AAR04347.1 399 phosphatase and tensin-like protein B short splice variant [Danio rerio]
GI:49227345 GenBank AAI07963.1 399 Phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) [Danio rerio]

Related Sequences to LMP011623 proteins

Reference Database Accession Length Protein Name
GI:49227345 GenBank AAR04346.1 422 phosphatase and tensin-like protein B long splice variant [Danio rerio]
GI:49227345 GenBank AHH38853.1 402 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [Ictalurus punctatus]
GI:49227345 RefSeq XP_003224419.1 404 PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [Anolis carolinensis]
GI:49227345 RefSeq XP_003964007.1 412 PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like isoform 1 [Takifugu rubripes]
GI:49227345 RefSeq XP_005474271.1 400 PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like isoform X5 [Oreochromis niloticus]
GI:49227345 RefSeq XP_005914181.1 394 PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like isoform X2 [Haplochromis burtoni]