Gene/Proteome Database (LMPD)

LMPD ID
LMP011769
Gene ID
406623
Species
Danio rerio (Zebrafish)
Gene Name
2,4-dienoyl CoA reductase 2, peroxisomal
Gene Symbol
decr2
Synonyms
zgc:85626; zC153C20.5
Alternate Names
peroxisomal 2,4-dienoyl-CoA reductase; 2,4-dienoyl-CoA reductase 2
Chromosome
24
EC Number
1.3.1.34

Proteins

peroxisomal 2,4-dienoyl-CoA reductase
Refseq ID NP_998486
Protein GI 47086965
UniProt ID Q6NV34
mRNA ID NM_213321
Length 300
RefSeq Status PROVISIONAL
MAEKPQLVNNLPEDVETDECMNKYTHIYSPDLLSDQVAFITGGGSGIGFRIAEVLMRHGCDTVIASRNLEKISQAAKKLTSTTGRRCLPIAMDVRQPETILAAVDETLKTFGRVDILINNAAGNFLCPATSLSFNAFKTVMEIDTMGTFNTSKVIYDKWFKDHGGSIVNISATLGYRGQALQVHAGSAKAANDAMTRHLAVEWGPSGVRVNTVAPGPISGTEGYRRLGGSHAETAGAFHSIPLQRAGNKTEMAHAVLFLASRASSYVTGSVLVADGGAWLTSANDVERLLGIVSSRSAKL

Gene Information

Entrez Gene ID
406623
Gene Name
2,4-dienoyl CoA reductase 2, peroxisomal
Gene Symbol
decr2
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005777 IEA:UniProtKB-KW C peroxisome
GO:0008670 ISS:UniProtKB F 2,4-dienoyl-CoA reductase (NADPH) activity
GO:0006631 IEA:UniProtKB-KW P fatty acid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
dre04146 Peroxisome
ko04146 Peroxisome

Domain Information

InterPro Annotations

Accession Description
IPR002347 Glucose/ribitol dehydrogenase
IPR016040 NAD(P)-binding domain
IPR002198 Short-chain dehydrogenase/reductase SDR

UniProt Annotations

Entry Information

Gene Name
2,4-dienoyl CoA reductase 2, peroxisomal
Protein Entry
DECR2_DANRE
UniProt ID
Q6NV34
Species
Zebrafish

Comments

Comment Type Description
Catalytic Activity Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH.
Function Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA (By similarity). {ECO:0000250}.
Similarity Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. {ECO:0000305}.
Subcellular Location Peroxisome {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011769 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
47086965 RefSeq NP_998486 300 peroxisomal 2,4-dienoyl-CoA reductase

Identical Sequences to LMP011769 proteins

Reference Database Accession Length Protein Name
GI:47086965 GenBank AAH68332.1 300 2,4-dienoyl CoA reductase 2, peroxisomal [Danio rerio]
GI:47086965 SwissProt Q6NV34.1 300 RecName: Full=Peroxisomal 2,4-dienoyl-CoA reductase; AltName: Full=2,4-dienoyl-CoA reductase 2 [Danio rerio]

Related Sequences to LMP011769 proteins

Reference Database Accession Length Protein Name
GI:47086965 GenBank AHH41676.1 293 Peroxisomal 2,4-dienoyl-CoA reductase [Ictalurus punctatus]
GI:47086965 RefSeq XP_005162937.1 301 PREDICTED: peroxisomal 2,4-dienoyl-CoA reductase isoform X1 [Danio rerio]
GI:47086965 RefSeq XP_005448303.1 300 PREDICTED: peroxisomal 2,4-dienoyl-CoA reductase-like isoform X3 [Oreochromis niloticus]
GI:47086965 RefSeq XP_007232106.1 294 PREDICTED: peroxisomal 2,4-dienoyl-CoA reductase-like isoform X1 [Astyanax mexicanus]
GI:47086965 RefSeq XP_007232107.1 294 PREDICTED: peroxisomal 2,4-dienoyl-CoA reductase-like isoform X2 [Astyanax mexicanus]
GI:47086965 RefSeq XP_007232108.1 293 PREDICTED: peroxisomal 2,4-dienoyl-CoA reductase-like isoform X3 [Astyanax mexicanus]