Gene/Proteome Database (LMPD)

LMPD ID
LMP011998
Gene ID
553949
Species
Danio rerio (Zebrafish)
Gene Name
FCH domain only 2
Gene Symbol
fcho2
Synonyms
cb304; sb:cb304; wu:fa01a02; zgc:112167; si:ch211-195c22.1
Alternate Names
FCH domain only protein 2
Chromosome
5

Proteins

FCH domain only protein 2
Refseq ID NP_001018617
Protein GI 66472804
UniProt ID Q502I9
mRNA ID NM_001020781
Length 848
RefSeq Status PROVISIONAL
MITPYFLENFWGNKNSGFYVLYHNMKHGQISSKELSDFIRERATIEEAYSRSMTKLAKTASNFSQLGTFAPVWDVFKQSTEKLAACHMELVRKLQELIKEVQKYVDEQAKNHKKTKEEVASTLEAVHNIQSVSQALLKSKENYINKTLEQERMRKEGAKQGDLDKAGLKVKKATESYKSYVEKYATAKTEFEQRMTETAQKFQGIEEEHILRMQEIIHSYSLSVEETHIQIGEVQQEFVNNMENTSVESLIEKLAESRGTGKERPGPIEFEECNVSIATEGAKPRKRKTFAIPGRRKEKDTDSTESTEVEAVNASNGAPPGFYGAIDLHNANVPQLDDEGFCIRPEVNENDAKENSFYSSSDSEDEDEPRKFHVQIKPVQTNNGTHQHKVTIDELKASIGNISLSPTPAVHMKRNQSNDELARPKIPQPPLNDRFSSNDLLSLDPFGPTSTGSSSSLPQSSVPPPNRPTTPLGTSSIVPPPRPLSRPKLATGKLTGITESGRPFSPPKLLNSSPPPPAAPLARAESFSSLSSNTSLSASNTPTVEDDVFVGKLPTFEKRCETPAGTSRGPSPVTLASQDALPIAVAFTESVNAYFKGADPSKCIVKITGDMTLSFPSGIIKIFTSSPSPAVLSFKLLNASRLEQIMPNQQLLHSDSSQSDTNTKDFWMNMPALTSFLRKSSEQNPAASYYNVDILKYQVCSNGIQSTPLNLVVYWKCSRSTTDLRVDYRYNPEAMQPPAPLTNVQVLVPVNGGVMNMQSLPNAIWNAEQNKSLWKLSDISDKSENEGSGSLRAKFELSEGPSIPATLAVQFFSEGSSLSGVDMELAGSGYRLSLNKKRFATGRYMADC

Gene Information

Entrez Gene ID
553949
Gene Name
FCH domain only 2
Gene Symbol
fcho2
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005905 ISS:UniProtKB C coated pit
GO:0005886 ISS:UniProtKB C plasma membrane
GO:0005546 ISS:UniProtKB F phosphatidylinositol-4,5-bisphosphate binding
GO:0035091 ISS:UniProtKB F phosphatidylinositol binding
GO:0001786 ISS:UniProtKB F phosphatidylserine binding
GO:0048268 ISS:UniProtKB P clathrin coat assembly
GO:0072583 ISS:UniProtKB P clathrin-mediated endocytosis
GO:0010324 ISS:UniProtKB P membrane invagination
GO:0072659 ISS:UniProtKB P protein localization to plasma membrane

Domain Information

InterPro Annotations

Accession Description
IPR001060 FCH domain
IPR028565 Mu homology domain
IPR018808 Muniscin C-terminal

UniProt Annotations

Entry Information

Gene Name
FCH domain only 2
Protein Entry
FCHO2_DANRE
UniProt ID
Q502I9
Species
Zebrafish

Comments

Comment Type Description
Function May function in an early step of clathrin-mediated endocytosis. {ECO:0000250}.
Similarity Belongs to the FCHO family. {ECO:0000305}.
Similarity Contains 1 FCH domain. {ECO:0000255|PROSITE- ProRule:PRU00083}.
Similarity Contains 1 MHD (mu homology) domain. {ECO:0000255|PROSITE-ProRule:PRU00404}.
Subcellular Location Membrane, clathrin-coated pit {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Subunit Homodimer. {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011998 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
66472804 RefSeq NP_001018617 848 FCH domain only protein 2

Identical Sequences to LMP011998 proteins

Reference Database Accession Length Protein Name
GI:66472804 GenBank AAH95680.1 848 FCH domain only 2 [Danio rerio]
GI:66472804 SwissProt Q502I9.1 848 RecName: Full=FCH domain only protein 2 [Danio rerio]

Related Sequences to LMP011998 proteins

Reference Database Accession Length Protein Name
GI:66472804 RefSeq XP_008274402.1 888 PREDICTED: FCH domain only protein 2 isoform X5 [Stegastes partitus]
GI:66472804 RefSeq XP_008274403.1 860 PREDICTED: FCH domain only protein 2 isoform X6 [Stegastes partitus]
GI:66472804 RefSeq XP_008274404.1 845 PREDICTED: FCH domain only protein 2 isoform X7 [Stegastes partitus]
GI:66472804 RefSeq XP_008323890.1 845 PREDICTED: FCH domain only protein 2 isoform X6 [Cynoglossus semilaevis]
GI:66472804 RefSeq XP_009299764.1 863 PREDICTED: FCH domain only protein 2 isoform X7 [Danio rerio]
GI:66472804 RefSeq XP_009299766.1 843 PREDICTED: FCH domain only protein 2 isoform X8 [Danio rerio]