Gene/Proteome Database (LMPD)

LMPD ID
LMP012058
Gene ID
559339
Species
Danio rerio (Zebrafish)
Gene Name
vacuolar protein sorting 51 homolog (S. cerevisiae)
Gene Symbol
vps51
Synonyms
ffr; c11orf2; fi30b05; wu:fi30b05
Alternate Names
vacuolar protein sorting-associated protein 51 homolog; fat free; fat-free; protein fat-free
Chromosome
10

Proteins

vacuolar protein sorting-associated protein 51 homolog
Refseq ID NP_001036200
Protein GI 112293301
UniProt ID Q155U0
mRNA ID NM_001042735
Length 827
RefSeq Status PROVISIONAL
MSSATTPPDSDPAQRRRVHSMLKLYYGLNEEGKATEQAESLDPCDINGPHFDPEIYLNKLRKECSLTELMDHESCMVKQIRSLDSDMQTLVYENYNKFISATDTIRKMKNDFKKMEDEMDCLSANMAAITEFSARISGTLQDQHAQITKLSGVHTLLRKLQFLFELPARLNKCLELQAYAQAVSSHRRARCVLQQYSHMPSFRGIQDDCHVIMEQLAQQLRQKFRDGGSSAKDLSECVELLLQLDEPAEELCDKFLSHAQSRLEADLQGLEAELKDSAVTDTGAGSVQKTSPGSNPVSPSSSVSNPFLSPAAGTDILEFIDRGCNEFVSNLCLVIASYQELFINRPQESELASKNIPEMANGKLHVFVDTLAARYFSLVERRIQEEKGVGDNSLLVRALDRFHRRLQAISKLLPGSAVPSQGTEIVVRAARERIKQYLSALQTFYHDSLTDVRQALAAPRLSVGGASASGGGALVGGASSKDAPPSLPELLTSLSNFILNQLKSVLASVHLFTAKDITFSNKPYFKGEFCSQGVREGLVVSFIKFICQSSRQYCESAGDRGGSTPPALLLLLSRLCLDYETSTISYILTLTDEQFLVQHHTPVTPVTALCAEAREAAQKLLNHYVKVQGLIISQMLRKSVETRDWVNTIEPRNVRAVMKRVVEDTTSIDVQVGLLYEEGVRKAHSSDSSKRTFSVYSSSRQQIRYAPSYTPSAPMDTNLLSNIHKLFSERIDIFSPVEFNKVSVLTGIIKISLKTFLECVRLRTFGRYGLQQIQVDCHYLQMYLWRFVSDENLVHFLLDEIVGSAAHRCLDPSPMEQSVIEVICERG

Gene Information

Entrez Gene ID
559339
Gene Name
vacuolar protein sorting 51 homolog (S. cerevisiae)
Gene Symbol
vps51
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0030306 IPI:ZFIN F ADP-ribosylation factor binding
GO:0007030 IMP:ZFIN P Golgi organization
GO:0048193 IMP:ZFIN P Golgi vesicle transport
GO:0044241 IMP:ZFIN P lipid digestion
GO:0006869 IEA:UniProtKB-KW P lipid transport
GO:0015031 IEA:UniProtKB-KW P protein transport
GO:0010517 IMP:ZFIN P regulation of phospholipase activity

Domain Information

InterPro Annotations

Accession Description
IPR016159 Cullin repeat-like-containing domain

UniProt Annotations

Entry Information

Gene Name
vacuolar protein sorting 51 homolog (S. cerevisiae)
Protein Entry
VPS51_DANRE
UniProt ID
Q155U0
Species
Zebrafish

Comments

Comment Type Description
Disruption Phenotype Larvae are morphologically indistinguishable from wild-type sibling larvae, but their absorption of lipids is severely impaired. {ECO:0000269|PubMed:16581006}.
Function May act as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). Regulator of vesicle recycling and protein sorting. Required for both Golgi structure and vesicular trafficking, and ultimately lipid transport. {ECO:0000269|PubMed:16581006}.
Similarity Belongs to the VPS51 family. {ECO:0000305}.
Subcellular Location Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:16581006}. Note=Also localizes in perinuclear region.
Subunit Component of the Golgi-associated retrograde protein (GARP) complex. {ECO:0000250}.
Tissue Specificity Ubiquitously expressed in adult. {ECO:0000269|PubMed:16581006}.

Identical and Related Proteins

Unique RefSeq proteins for LMP012058 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
112293301 RefSeq NP_001036200 827 vacuolar protein sorting-associated protein 51 homolog

Identical Sequences to LMP012058 proteins

Reference Database Accession Length Protein Name
GI:112293301 GenBank ABG23689.1 827 fat-free protein [Danio rerio]
GI:112293301 GenBank AAI62802.1 827 C11orf2 homolog (H. sapiens) [Danio rerio]
GI:112293301 GenBank AAI62801.1 827 C11orf2 homolog (H. sapiens) [Danio rerio]
GI:112293301 SwissProt Q155U0.1 827 RecName: Full=Vacuolar protein sorting-associated protein 51 homolog; AltName: Full=Protein fat-free [Danio rerio]

Related Sequences to LMP012058 proteins

Reference Database Accession Length Protein Name
GI:112293301 EMBL CDQ63549.1 823 unnamed protein product [Oncorhynchus mykiss]
GI:112293301 GenBank ACN10537.1 840 C11orf2 [Salmo salar]
GI:112293301 RefSeq NP_001158820.1 840 CK002 protein [Salmo salar]
GI:112293301 RefSeq XP_005932018.1 823 PREDICTED: vacuolar protein sorting-associated protein 51 homolog isoform X1 [Haplochromis burtoni]
GI:112293301 RefSeq XP_006799509.1 823 PREDICTED: vacuolar protein sorting-associated protein 51 homolog [Neolamprologus brichardi]
GI:112293301 RefSeq XP_008284290.1 834 PREDICTED: vacuolar protein sorting-associated protein 51 homolog [Stegastes partitus]