Gene/Proteome Database (LMPD)

LMPD ID
LMP012080
Gene ID
561747
Species
Danio rerio (Zebrafish)
Gene Name
phospholipase C, gamma 2
Gene Symbol
plcg2
Synonyms
fj85b03; wu:fj85b03; zgc:152893; si:ch211-260p9.2
Chromosome
18

Proteins

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Refseq ID NP_001038433
Protein GI 113678764
UniProt ID Q1LWV8
mRNA ID NM_001044968
Length 1240
RefSeq Status PROVISIONAL
MAGRAHQGDLTEYKKSLIKRDLEMGIVMTVYRQRIERLTVQVIMETRQVAWSRTANKTEGVLDIFEIREVRPGKNSKEFDRFKDHKDRNTDPNTCFTIFYGSQFVLNTLSLGADSVEDAEKWLTGLELLRDETLAAHTPEIIESWLRKQMYSVDQTKKNSITMKELKSLLPQMNFKVPCGRFLKDKFAALGAKKEVLDFEQFHKFYNSLIFENQKSILDEFKKETCAFILGNGDQPIQLSDFQRFLLYQQRETWANNLNQVRELMTIFIDDTMRETNDPAFILEEFLSFLFSKENQIWDDKFSEICPLDMNNPLSHYWINSSHNTYLTGDQLRSESSTEAYVRCLRLGCRCVELDCWNGPEEPIIYHGWTRTSKIKFKDVVKAINDHAFATSEYPVVLSIEEHCDVKQQKMMAQVFKDVFQDKILMEPLEPEAEQLPSPTQLKGKIIIKHKKLNIDQTFGRKDLRKGDKQGELFIWDPIDERWYRHYCVIENKTLYYAEENDEEEEKSVQSCTELHQSEPWFHGRMSEGRMTAERLLQEYCAESGGVDGTFLVRESDTFVNDCTLSFWRSGRVQHCRIRSCLEGGHTVYFLTENLHFPSVYALIYYYRDNLLRCQDFNLRLTEYVPKPDTHQLEGWFYSNLSRGEAEDYLMRIPRDGAFLIRQREDSDSYAITFRGEGLVKHCRIHKDGSMYILGTSSEFDSLVELVDYFRKKPLYRKTKLRYPVTPELVERFSSINKTGSLYDSKQYVEANEIEPSLPQNTVKALYDYRAMRPDELTFSKGVLIHNVTRDTNGWWKGDYGGKLQHYFPSNYVEEVQSDANYQPEEENPLGELCKGTVDISKCTVVRSAKHGKQVVVTLQYKEDKENMMPFDLATETTEELYEWYQVAWDITQREENLVFEKEKTKEVETRDEVASEMSELVVYCQPRSKEKDGFDNYTYKEVRSFVENKTPSRNKLTQFMLYNRKALSRIYPKGQRVDSSNYDPYPLWMCGCHMVALNFQTADKYTQLNSALFSLNGSTGYVLQPELMRRDSYDPQQERKNIKYTIGIRVIGARHLPKPGRSIASPFVEIELCGQTDESKFKTTVCHDNGLNPIWQPSEMFVFSVYEPDLTFLRFVVFEEDMFSDPNFLAQATFPVKGVRSGYRSVPLKNGFSENLELASLLVCVDVQQVEKAQEELYSSSKQLQKKQAEMSSEFCLYDTHSNLRSSGPQRREDLSQFTYSEKKINKPQQKINNSKFYS

Gene Information

Entrez Gene ID
561747
Gene Name
phospholipase C, gamma 2
Gene Symbol
plcg2
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0009395 IEA:InterPro P phospholipid catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR028381 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
IPR000008 C2 domain
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR016279 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain
IPR000980 SH2 domain
IPR001452 SH3_domain

UniProt Annotations

Entry Information

Gene Name
phospholipase C, gamma 2
Protein Entry
Q1LWV8_DANRE
UniProt ID
Q1LWV8
Species
Zebrafish

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains 1 SH3 domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PH domain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP012080 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
113678764 RefSeq NP_001038433 1240 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

Identical Sequences to LMP012080 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP012080 proteins

Reference Database Accession Length Protein Name
GI:113678764 GenBank AAI24601.1 1240 Phospholipase C, gamma 2 [Danio rerio]
GI:113678764 GenBank AAI64582.1 1240 Plcg2 protein [Danio rerio]
GI:113678764 GenBank AHH42369.1 1263 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [Ictalurus punctatus]
GI:113678764 RefSeq XP_005449270.1 1249 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [Oreochromis niloticus]
GI:113678764 RefSeq XP_007251008.1 1204 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2-like isoform X1 [Astyanax mexicanus]
GI:113678764 RefSeq XP_007251009.1 1204 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2-like isoform X2 [Astyanax mexicanus]