Gene/Proteome Database (LMPD)
LMPD ID
LMP012130
Gene ID
Species
Danio rerio (Zebrafish)
Gene Name
1-acylglycerol-3-phosphate O-acyltransferase 9, like
Gene Symbol
Synonyms
si:ch211-155m12.4
Alternate Names
glycerol-3-phosphate acyltransferase 3-like; 1-AGPAT 9-like; LPAAT-theta-like; 1-AGP acyltransferase 9-like; lysophosphatidic acid acyltransferase theta-like; 1-acylglycerol-3-phosphate O-acyltransferase 9-like; 1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9-like
Chromosome
5
EC Number
2.3.1.15
Proteins
| glycerol-3-phosphate acyltransferase 3-like | |
|---|---|
| Refseq ID | NP_001092920 |
| Protein GI | 150832527 |
| UniProt ID | A3KGT9 |
| mRNA ID | NM_001099450 |
| Length | 443 |
| RefSeq Status | PROVISIONAL |
| MEGYWAVLFPVLKVWFSCVIVLIMLPAMFGISLGITETYMKLLIKTLEWATHRIQRASRAEEILKESASNGLIQRDNSSLEQEIEELRRNRPKSADRGDFTLSDVLYFSRKGFESIVEDDVTQRFTSEELVSWNLLTRTNNNFQYISLRLTVLWVVGVVVRYCILLPLRITLTTIGLTWLVIGTTTVGFLPNCRVKNWLSELVHLMCYRICARGLSATIHFHNKQNRPKKGGICVANHTSPIDVVILANDGCYAMVGQVHGGLMGVLQRAMERSCPHIWFERSEMRDRHLVTQRLKDHVNAKTKLPILIFPEGTCINNTSVMMFKKGSFEIGGTIYPVAIKYDPQFGDAFWNSSKYSIMSYLLRMMTSWAIVCNVWYLPPMTHEEGEDAVQFANRVKSTIAQQGGLVDLAWDGGLKRAKVKDSFKEQQQKKYSHMVVGEDSSD | |
Gene Information
Entrez Gene ID
Gene Name
1-acylglycerol-3-phosphate O-acyltransferase 9, like
Gene Symbol
Species
Danio rerio
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005789 | ISS:UniProtKB | C | endoplasmic reticulum membrane |
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0003841 | IEA:UniProtKB-EC | F | 1-acylglycerol-3-phosphate O-acyltransferase activity |
| GO:0004366 | ISS:UniProtKB | F | glycerol-3-phosphate O-acyltransferase activity |
| GO:0016024 | IEA:UniProtKB-UniPathway | P | CDP-diacylglycerol biosynthetic process |
| GO:0019432 | ISS:UniProtKB | P | triglyceride biosynthetic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| dre00561 | Glycerolipid metabolism |
| dre00564 | Glycerophospholipid metabolism |
| dre01100 | Metabolic pathways |
| dre_M00089 | Triacylglycerol biosynthesis |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR002123 | Phospholipid/glycerol acyltransferase |
UniProt Annotations
Entry Information
Gene Name
1-acylglycerol-3-phosphate O-acyltransferase 9, like
Protein Entry
GPT3L_DANRE
UniProt ID
Species
Zebrafish
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. |
| Catalytic Activity | Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1- acyl-sn-glycerol 3-phosphate. |
| Caution | Despite its name, the human homolog of this protein appears to lack measurable glycerol-3-phosphate acyltransferase activity under some conditions (PMID:19318427). {ECO:0000305}. |
| Domain | The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}. |
| Function | May transfer the acyl-group from acyl-coA to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Also transfers the acyl-group from acyl-coA to the sn-2 position of 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid, or LPA), forming 1,2-diacyl-sn-glycerol-3- phosphate (phosphatidic acid, or PA) (By similarity). {ECO:0000250}. |
| Pathway | Glycerolipid metabolism; triacylglycerol biosynthesis. |
| Pathway | Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. |
| Similarity | Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. {ECO:0000305}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP012130 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 150832527 | RefSeq | NP_001092920 | 443 | glycerol-3-phosphate acyltransferase 3-like |
Identical Sequences to LMP012130 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:150832527 | SwissProt | A3KGT9.1 | 443 | RecName: Full=Glycerol-3-phosphate acyltransferase 3-like; AltName: Full=1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9-like; Short=1-AGP acyltransferase 9-like; Short=1-AGPAT 9-like; AltName: Full=Lysophosphatidic acid acyltransferase theta-like; Short=LPAAT-theta-like [Danio rerio] |
Related Sequences to LMP012130 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:150832527 | GenBank | AHH42526.1 | 443 | Glycerol-3-phosphate acyltransferase 3 [Ictalurus punctatus] |
| GI:150832527 | RefSeq | XP_006627216.1 | 443 | PREDICTED: glycerol-3-phosphate acyltransferase 3-like [Lepisosteus oculatus] |
| GI:150832527 | RefSeq | XP_007563598.1 | 446 | PREDICTED: glycerol-3-phosphate acyltransferase 3-like [Poecilia formosa] |
| GI:150832527 | RefSeq | XP_007563599.1 | 446 | PREDICTED: glycerol-3-phosphate acyltransferase 3-like [Poecilia formosa] |
| GI:150832527 | RefSeq | XP_008416327.1 | 446 | PREDICTED: glycerol-3-phosphate acyltransferase 3-like [Poecilia reticulata] |
| GI:150832527 | RefSeq | XP_008416328.1 | 446 | PREDICTED: glycerol-3-phosphate acyltransferase 3-like [Poecilia reticulata] |