Gene/Proteome Database (LMPD)

LMPD ID
LMP012241
Gene ID
791641
Species
Danio rerio (Zebrafish)
Gene Name
ceramide-1-phosphate transfer protein
Gene Symbol
cptp
Synonyms
gltpd1; fb75f03; zgc:92000; wu:fb75f03
Alternate Names
ceramide-1-phosphate transfer protein; glycolipid transfer protein domain containing 1; glycolipid transfer protein domain-containing protein 1
Chromosome
23

Proteins

ceramide-1-phosphate transfer protein
Refseq ID NP_001003497
Protein GI 51011077
UniProt ID Q6DBQ8
mRNA ID NM_001003497
Length 211
RefSeq Status PROVISIONAL
MADAFSLQRVLETFRSSLSENKEVYIKYYIAGWQELVSFMNSLGNVFSFISKDVVSKIQILENFLSGENGSNYVTIQSMVKYELENDLVDLTKRGSHPESGCRTLLRLHRALRWLELFLERLRTSTEDSKTSVMCSDAYNESLANHHPWLIRKAVGVAFCALPGRETFFDVMNAGDHTQVVALLGESLPLIAEVYQITEDLYAKNNLLELP

Gene Information

Entrez Gene ID
791641
Gene Name
ceramide-1-phosphate transfer protein
Gene Symbol
cptp
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005768 IEA:UniProtKB-KW C endosome
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0005634 IEA:UniProtKB-KW C nucleus
GO:0005886 IEA:UniProtKB-KW C plasma membrane
GO:1902387 ISS:UniProtKB F ceramide 1-phosphate binding
GO:1902388 ISS:UniProtKB F ceramide 1-phosphate transporter activity
GO:0051861 IEA:InterPro F glycolipid binding
GO:0017089 IEA:InterPro F glycolipid transporter activity
GO:0005543 ISS:UniProtKB F phospholipid binding
GO:0005548 ISS:UniProtKB F phospholipid transporter activity
GO:1902389 ISS:UniProtKB P ceramide 1-phosphate transport

Domain Information

InterPro Annotations

Accession Description
IPR014830 Glycolipid transfer protein domain

UniProt Annotations

Entry Information

Gene Name
ceramide-1-phosphate transfer protein
Protein Entry
CPTP_DANRE
UniProt ID
Q6DBQ8
Species
Zebrafish

Comments

Comment Type Description
Function Mediates the intracellular transfer of ceramide-1- phosphate between organelle membranes and the cell membrane. Required for normal structure of the Golgi stacks. Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). Plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid. Has no activity with galactosylceramide, lactosylceramide, sphingomyelin, phosphatidylcholine, phosphatidic acid and ceramide (By similarity). {ECO:0000250}.
Similarity Belongs to the GLTP family. {ECO:0000305}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus outer membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP012241 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
51011077 RefSeq NP_001003497 211 ceramide-1-phosphate transfer protein

Identical Sequences to LMP012241 proteins

Reference Database Accession Length Protein Name
GI:51011077 GenBank AAH78407.1 211 Zgc:92000 [Danio rerio]
GI:51011077 SwissProt Q6DBQ8.1 211 RecName: Full=Ceramide-1-phosphate transfer protein; AltName: Full=Glycolipid transfer protein domain-containing protein 1; Short=CPTP [Danio rerio]

Related Sequences to LMP012241 proteins

Reference Database Accession Length Protein Name
GI:51011077 EMBL CDQ76885.1 218 unnamed protein product [Oncorhynchus mykiss]
GI:51011077 EMBL CDQ72992.1 216 unnamed protein product [Oncorhynchus mykiss]
GI:51011077 GenBank AHH37646.1 211 Ceramide-1-phosphate transfer protein [Ictalurus punctatus]
GI:51011077 RefSeq XP_004560419.1 218 PREDICTED: glycolipid transfer protein domain-containing protein 1-like isoform X1 [Maylandia zebra]
GI:51011077 RefSeq XP_005918923.1 218 PREDICTED: glycolipid transfer protein domain-containing protein 1-like isoform X1 [Haplochromis burtoni]
GI:51011077 RefSeq XP_007237908.1 211 PREDICTED: ceramide-1-phosphate transfer protein [Astyanax mexicanus]