Gene/Proteome Database (LMPD)

LMPD ID
LMP012242
Gene ID
791732
Species
Danio rerio (Zebrafish)
Gene Name
sulfotransferase family 1, cytosolic sulfotransferase 2
Gene Symbol
sult1st2
Chromosome
8

Proteins

cytosolic sulfotransferase 2
Refseq ID NP_899190
Protein GI 47271425
UniProt ID Q7ZUS4
mRNA ID NM_183347
Length 301
RefSeq Status PROVISIONAL
MEIPDFSSMKLDSRPELIDFEGVSMTRYFTDNWEKVKNFQARPDDILIATYPKAGTTWVSYILDLLYFGNESPERQTSQPIYMRVPFLEMCFQGLPLGTELADTLPTSPRPIKTHLPVQLVPKSFWEQNSKVVYVARNAKDNAVSYFHFDRMNMGQPEPGDWNTFLQKFMDGRNVFGPWYDHVNGYWKKKQTYSNILYMFYEDMVEDTGREVARLCSFLGLSTSATERERITKGVQFDVMKQNKMTNYSTLPVMDFKISPFMRKGKVGDWRNHFTVAQNEQFDEVYKQKMKNTTVKFRTEI

Gene Information

Entrez Gene ID
791732
Gene Name
sulfotransferase family 1, cytosolic sulfotransferase 2
Gene Symbol
sult1st2
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 NAS:UniProtKB C cytoplasm
GO:0004304 IDA:ZFIN F estrone sulfotransferase activity
GO:0008146 IDA:UniProtKB F sulfotransferase activity
GO:0006584 IEA:UniProtKB-KW P catecholamine metabolic process
GO:0008210 IDA:ZFIN P estrogen metabolic process
GO:0006805 IDA:UniProtKB P xenobiotic metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR000863 Sulfotransferase domain

UniProt Annotations

Entry Information

Gene Name
sulfotransferase family 1, cytosolic sulfotransferase 2
Protein Entry
Q7ZUS4_DANRE
UniProt ID
Q7ZUS4
Species
Zebrafish

Comments

Comment Type Description
Biophysicochemical Properties pH dependence: Optimum pH is 4.75 and 10.5. These two pH optima may correspond to two distinct conformational states of the enzyme.; Temperature dependence: Active from 20 to 43 degrees Celsius.;
Enzyme Regulation Inhibited by Co(2+), Zn(2+), Cd(2+) and Pb(2+) ions. Inactivated by Hg(2+) and Cu(2+) ions.
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L- thyronine), T4 (thyroxine), estrone and DOPA.
Similarity Belongs to the sulfotransferase 1 family.
Subcellular Location Cytoplasm.
Tissue Specificity Expressed in liver.

Identical and Related Proteins

Unique RefSeq proteins for LMP012242 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
47271425 RefSeq NP_899190 301 cytosolic sulfotransferase 2

Identical Sequences to LMP012242 proteins

Reference Database Accession Length Protein Name
GI:47271425 GenBank AAH47850.1 301 Sulfotransferase family 1, cytosolic sulfotransferase 2 [Danio rerio]
GI:47271425 SwissProt Q7ZUS4.1 301 RecName: Full=Cytosolic sulfotransferase 2; AltName: Full=SULT1 ST2 [Danio rerio]

Related Sequences to LMP012242 proteins

Reference Database Accession Length Protein Name
GI:47271425 GenBank AAP55637.1 301 SULT1 sulfotransferase isoform 3 [Danio rerio]
GI:47271425 GenBank AAO64984.1 301 SULT1 sulfotransferase isoform 2 [Danio rerio]
GI:47271425 GenBank AAH76007.1 301 Sulfotransferase family 1, cytosolic sulfotransferase 3 [Danio rerio]
GI:47271425 RefSeq NP_899191.2 301 cytosolic sulfotransferase 3 [Danio rerio]
GI:47271425 RefSeq XP_005172522.1 301 PREDICTED: cytosolic sulfotransferase 3 isoform X1 [Danio rerio]
GI:47271425 RefSeq XP_005172533.1 301 PREDICTED: cytosolic sulfotransferase 2 isoform X1 [Danio rerio]