Gene/Proteome Database (LMPD)

LMPD ID
LMP012271
Gene ID
798384
Species
Danio rerio (Zebrafish)
Gene Name
cholesterol 25-hydroxylase like 1, tandem duplicate 2
Gene Symbol
ch25hl1.2
Synonyms
si:dkey-24l11.9
Alternate Names
cholesterol 25-hydroxylase-like protein 1, member 2; ch25hl1.2; cholesterol 25-hydroxylase like 1, member 2
Chromosome
18
EC Number
1.14.99.-

Proteins

cholesterol 25-hydroxylase-like protein 1, member 2
Refseq ID NP_001076393
Protein GI 130492487
UniProt ID Q1LX59
mRNA ID NM_001082924
Length 276
RefSeq Status PROVISIONAL
MTLAHIFQTIWDFGTKDSVLQPIWDYVRLNHSETLRSPLFPVVLTVSSYFVLVLPYLSCDILGRKWPAIYRYKIQPDKLPTTAMLLHCSGVTLYNHILLVIPAAVAQWMWRPPIPLPEQAPTLLELVGGVTGNLLLFDLQYFIWHFLHHKIRWLYVTFHAIHHNYSAPFALATQCLGGWELVTVGFWTTLNPVLLRCHLLTTWMFMVVHVYVSVEDHCGYDFPWSTSRLIPFGVYGGPSKHDVHHQKPNTNFAPHFSHWDKMFGTHADFRFSKPRE

Gene Information

Entrez Gene ID
798384
Gene Name
cholesterol 25-hydroxylase like 1, tandem duplicate 2
Gene Symbol
ch25hl1.2
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005506 IEA:InterPro F iron ion binding
GO:0004497 IEA:UniProtKB-KW F monooxygenase activity
GO:0006633 IEA:InterPro P fatty acid biosynthetic process
GO:0016126 IEA:UniProtKB-KW P sterol biosynthetic process

REACTOME Pathway Links

REACTOME Pathway ID Description
6176066 Bile acid and bile salt metabolism
6175604 Metabolism
6175643 Metabolism of lipids and lipoproteins
6176269 Synthesis of bile acids and bile salts

Domain Information

InterPro Annotations

Accession Description
IPR006694 Fatty_acid_hydroxylase

UniProt Annotations

Entry Information

Gene Name
cholesterol 25-hydroxylase like 1, tandem duplicate 2
Protein Entry
C2512_DANRE
UniProt ID
Q1LX59
Species
Zebrafish

Comments

Comment Type Description
Cofactor Name=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000250|UniProtKB:Q9Z0F5};
Function May catalyze the formation of 25-hydroxycholesterol from cholesterol. {ECO:0000250|UniProtKB:Q9Z0F5}.
Similarity Belongs to the sterol desaturase family. {ECO:0000255}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9Z0F5}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Z0F5}.

Identical and Related Proteins

Unique RefSeq proteins for LMP012271 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
130492487 RefSeq NP_001076393 276 cholesterol 25-hydroxylase-like protein 1, member 2

Identical Sequences to LMP012271 proteins

Reference Database Accession Length Protein Name
GI:130492487 SwissProt Q1LX59.1 276 RecName: Full=Cholesterol 25-hydroxylase-like protein 1, member 2 [Danio rerio]

Related Sequences to LMP012271 proteins

Reference Database Accession Length Protein Name
GI:130492487 RefSeq XP_004553226.1 277 PREDICTED: cholesterol 25-hydroxylase-like protein 1, member 2-like [Maylandia zebra]
GI:130492487 RefSeq XP_005470799.1 277 PREDICTED: cholesterol 25-hydroxylase-like protein 1, member 2-like isoform X1 [Oreochromis niloticus]
GI:130492487 RefSeq XP_005730209.1 277 PREDICTED: cholesterol 25-hydroxylase-like protein 1, member 2-like [Pundamilia nyererei]
GI:130492487 RefSeq XP_005928760.1 277 PREDICTED: cholesterol 25-hydroxylase-like protein 1, member 2-like [Haplochromis burtoni]
GI:130492487 RefSeq XP_007241992.1 272 PREDICTED: cholesterol 25-hydroxylase-like protein 1, member 2-like [Astyanax mexicanus]
GI:130492487 RefSeq XP_008410531.1 277 PREDICTED: cholesterol 25-hydroxylase-like protein 1, member 2 [Poecilia reticulata]