Gene/Proteome Database (LMPD)

LMPD ID
LMP012279
Gene ID
Species
Danio rerio (Zebrafish)
Gene Name
spinster homolog 1 (Drosophila)
Gene Symbol
Synonyms
nrs; spinl; wu:fb95b12; wu:fi37e11; etID64740.3
Alternate Names
protein spinster homolog 1; not really started; spinster-like protein; protein not really started
Chromosome
3

Proteins

protein spinster homolog 1
Refseq ID NP_705949
Protein GI 24119224
UniProt ID Q7ZU13
mRNA ID NM_153663
Length 506
RefSeq Status PROVISIONAL
MSQADADITPFFADDNEGEGPVENGVGSPLPEDEEEESPSGVTDRRAIMTVIVLCYINLLNYMDRFTVAGVLPDIEHFFGIGDGTSGLLQTVFICSYMFLAPLFGYLGDRYNRKLIMCVGIFFWSVVTLASSFIGKDHFWALLLTRGLVGVGEASYSTIAPTIIADLFVKEKRTNMLSIFYFAIPVGSGMGYIVGSKVDTVAKDWHWALRVTPGLGLLAVFLLMLVVQEPKRGAIEAHPEHTLHRTSWLADMKALCRNPSFILSTFGFTAVAFVTGSLALWAPAFLFRAGVFTGVKQPCFKAPCDDSDSLIFGAITVVTGILGVASGVQASKLLRTRTPRADPLVCAAGLLLAAPFLYLSIIFAQASTVATYVFIFLGETFLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAISPYLIGVVSDSIKESNSYMWEFRSLQMSLLLCSFVAVAGGAFFLATAVFIEKDRDLAENYVPSDDAPIVVPRSGRSTKVSVSSVLI

Gene Information

Entrez Gene ID
Gene Name
spinster homolog 1 (Drosophila)
Gene Symbol
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005743 IEA:UniProtKB-KW C mitochondrial inner membrane
GO:0006869 IEA:UniProtKB-KW P lipid transport
GO:0055085 IEA:InterPro P transmembrane transport

Domain Information

InterPro Annotations

Accession Description
IPR011701 Major facilitator superfamily
IPR020846 Major facilitator superfamily domain

UniProt Annotations

Entry Information

Gene Name
spinster homolog 1 (Drosophila)
Protein Entry
SPNS1_DANRE
UniProt ID
Species
Zebrafish

Comments

Comment Type Description
Developmental Stage Expressed both maternally and zygotically throughout embryogenesis, and also in adults. {ECO:0000269|PubMed:11836794}.
Disruption Phenotype Presence in early embryos of an opaque substance in the posterior yolk cell extension at approximately 1 day after fertilization. This material progressively accumulates and by 48 hours after fertilization fills the entire yolk. By day 3 of embryogenesis, embryos are severely reduced in size compared with their wild-type siblings and they die a few hours later. {ECO:0000269|PubMed:11836794, ECO:0000269|PubMed:18704191}.
Function Sphingolipid transporter. {ECO:0000250}.
Similarity Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family. {ECO:0000305}.
Subcellular Location Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Expressed in yolk cells. {ECO:0000269|PubMed:11836794}.

Identical and Related Proteins

Unique RefSeq proteins for LMP012279 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24119224 RefSeq NP_705949 506 protein spinster homolog 1

Identical Sequences to LMP012279 proteins

Reference Database Accession Length Protein Name
GI:24119224 GenBank AAL69987.1 506 not really started [Danio rerio]

Related Sequences to LMP012279 proteins

Reference Database Accession Length Protein Name
GI:24119224 EMBL CDQ87316.1 507 unnamed protein product [Oncorhynchus mykiss]
GI:24119224 EMBL CDQ70930.1 522 unnamed protein product [Oncorhynchus mykiss]
GI:24119224 GenBank AAH48024.1 506 Spinster homolog 1 (Drosophila) [Danio rerio]
GI:24119224 GenBank AAI65625.1 506 Spns1 protein [Danio rerio]
GI:24119224 RefSeq XP_005163889.1 504 PREDICTED: protein spinster homolog 1 isoform X1 [Danio rerio]
GI:24119224 SwissProt Q7ZU13.1 506 RecName: Full=Protein spinster homolog 1; AltName: Full=Protein not really started; AltName: Full=Spinster-like protein [Danio rerio]