Gene/Proteome Database (LMPD)

LMPD ID
LMP012289
Gene ID
100001532
Species
Danio rerio (Zebrafish)
Gene Name
phospholipase C, beta 3 (phosphatidylinositol-specific)
Gene Symbol
plcb3
Synonyms
she; Plcbeta3; wu:fl04b08; si:zc188c22.1; si:ch211-188c22.1
Chromosome
7

Proteins

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
Refseq ID NP_001116245
Protein GI 218563719
UniProt ID A2TJ25
mRNA ID NM_001122773
Length 1244
RefSeq Status PROVISIONAL
MAGAKPGVHALQLKPVSVNEVLKRGSKFIKWDEEANSTPSLITLRVDPNGFFLYWTGGTSMEAEILDMSHIRDTRTGKFAKTPKDQRIREMLFSGKADGNSDSRLLTVVYGNDLVNISFLNFQAVQDGYCKLWTDELFKLATNMLSQNASRNTFLLKAYTKLKLQVTQDGKIPVKNILKMFSDKKRVEMALEHCGLIFNRVDGIKPDDFTWEMFQNFLNKLSPRPEVERIFVDLGSKGKPFLSLDQLMDFINRKQRDSRLNEVLYPPLKRDQVRQLMEKYETNTSQLERDQISLMSFTKYLGGEENTVVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGCRCIELDCWKGRPPEEEPIITHGFTMTTEIPFKDVIEAIAESAFKTSPYPLILSFENHVDSAKQQAKMAEYCRSMFGDALLIDPLDKYPLVPGQQLPSPQELLGKILIKNKKKHHHRASNGGSIRRKDGTDEQSSPLNDCPLSDGDVGQLMSNGGEKLAERMAKDHDNSKSIDRGDGESDEEEEEEPIPDPKKHNNTDEGTAYSEVNATEEMSTLVNYIEPVKFKSFEVAAKRKKFFEMSSFVETKGMDTLKNSPTEFVEYNKKQMSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLDLAMQLNMGVFEYNGRCGYLLKPEFMRRTDKHFDPFTTDIVDGIVANTVKVKIISGQFLNDKKVGVYVEVDMFGLPADTKRKYRTKTSNNNSLDPVWDDETFVFNKVVLPTLASLRVAVYEENGKFIGHRILPVSALRPGYHYICLKNELNQPLMLPSLLVYTEVQDYIPNEHQEYAEALTNPIKHLSLLAQRESQLLALMEDPTEGGPTKQEEGDGTDSSCVTSADPIFPLPSSPTLPSVPTDLNPPPSGQKEDLVNNVLKVIEPESIDELKQHNSYLKLLKKQCKEFKELSKKHLKKMLALSKEQKTLFNQQSSELQRKRSQIEKRIRTSLKKNGSEDSVHRELNELDLELQKQMEQFREEHMQKLLVLRQGQLQMEKEVKQFHLKEANQKLKDIAIECQAAQIKKLKDVCDKEKKELQKMLDRKRLNSIVEARKAEKEIDVNEINRKHIQESVSLIRQLEVSQGKRQEKLKALHKDILQKIEEEIPMNQARLTRDFEAELKRLPEEISQYLQELESKGSRKDSLMGQTNDGPNSGPPSNCSTPPYSSPNHSWSNIANVSSLLLDSSTSSTSAKSETDTTGVY

Gene Information

Entrez Gene ID
100001532
Gene Name
phospholipase C, beta 3 (phosphatidylinositol-specific)
Gene Symbol
plcb3
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0007268 IEA:InterPro P synaptic transmission

Domain Information

InterPro Annotations

Accession Description
IPR028390 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
IPR000008 C2 domain
IPR011992 EF-hand domain pair
IPR014815 PLC-beta, C-terminal
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR016280 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
IPR009535 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta, conserved site
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like

UniProt Annotations

Entry Information

Gene Name
phospholipase C, beta 3 (phosphatidylinositol-specific)
Protein Entry
A2TJ25_DANRE
UniProt ID
A2TJ25
Species
Zebrafish

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP012289 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
218563719 RefSeq NP_001116245 1244 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

Identical Sequences to LMP012289 proteins

Reference Database Accession Length Protein Name
GI:218563719 GenBank ABM91767.1 1244 phospholipase C beta 3 [Danio rerio]

Related Sequences to LMP012289 proteins

Reference Database Accession Length Protein Name
GI:218563719 GenBank AHH37975.1 1246 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [Ictalurus punctatus]
GI:218563719 RefSeq XP_003452445.1 1253 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [Oreochromis niloticus]
GI:218563719 RefSeq XP_003977980.1 1252 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3-like [Takifugu rubripes]
GI:218563719 RefSeq XP_005166590.1 1245 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [Danio rerio]
GI:218563719 RefSeq XP_007242103.1 1251 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [Astyanax mexicanus]
GI:218563719 RefSeq XP_008303900.1 1257 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [Stegastes partitus]