Gene/Proteome Database (LMPD)

LMPD ID
LMP012492
Gene ID
25284
Species
Rattus norvegicus (Rat)
Gene Name
alpha-methylacyl-CoA racemase
Gene Symbol
Amacr
Synonyms
Da1-8; Marc1;
Alternate Names
alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase; 2-arylpropionyl-CoA epimerase;
Chromosome
2
Map Location
2q16
Summary
enzmyme that converts pristanoyl-CoA and C27-bile acyl-CoAs to (S)-stereoisomers; involved in the degradation of the side chain of bile acid intermediates [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Amacr

Proteins

alpha-methylacyl-CoA racemase
Refseq ID NP_036948
Protein GI 401709963
UniProt ID Q5BK88
mRNA ID NM_012816
Length 382
MALRGVRVLELAGLAPGPFCGMILADFGAEVVLVDRLGSVNHPSHLARGKRSLALDLKRSPGAAVLRRMCARADVLLEPFRCGVMEKLQLGPETLQQDNPKLIYARLSGFGQSGIFSKVAGHDINYVALSGVLSKIGRSGENPYPPLNLLADFGGGGLMCTLGILLALFERTRSGLGQVIDANMVEGTAYLSTFLWKTQAMGLWAQPRGQNLLDGGAPFYTTYKTADGEFMAVGAIEPQFYTLLLKGLGLESEELPSQMSIEDWPEVKKKFADVFARKTKAEWCQIFDGTDACVTPVLTLEEALHHQHNRERGSFITDEEQHASPRPAPQLSRTPAVPSAKRDPSVGEHTVEVLKDYGFSQEEIHQLHSDRIIESNKLKANL

Gene Information

Entrez Gene ID
25284
Gene Name
alpha-methylacyl-CoA racemase
Gene Symbol
Amacr
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0003824 IEA:InterPro F catalytic activity

KEGG Pathway Links

KEGG Pathway ID Description
rno01100 Metabolic pathways
ko04146 Peroxisome
rno04146 Peroxisome
ko00120 Primary bile acid biosynthesis
rno00120 Primary bile acid biosynthesis

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-6061 bile acid biosynthesis, neutral pathway

REACTOME Pathway Links

REACTOME Pathway ID Description
5954181 Beta-oxidation of pristanoyl-CoA
5953720 Bile acid and bile salt metabolism
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5953470 Peroxisomal lipid metabolism
5953930 Synthesis of bile acids and bile salts
5953933 Synthesis of bile acids and bile salts via 24-hydroxycholesterol
5953931 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

Domain Information

InterPro Annotations

Accession Description
IPR003673 CoA-transferase family III
IPR023606 CoA-transferase family III domain

UniProt Annotations

Entry Information

Gene Name
alpha-methylacyl-CoA racemase
Protein Entry
Q5BK88_RAT
UniProt ID
Q5BK88
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP012492 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
401709963 RefSeq NP_036948 382 alpha-methylacyl-CoA racemase

Identical Sequences to LMP012492 proteins

Reference Database Accession Length Protein Name
GI:401709963 GenBank EDL82982.1 382 alpha-methylacyl-CoA racemase [Rattus norvegicus]

Related Sequences to LMP012492 proteins

Reference Database Accession Length Protein Name
GI:401709963 GenBank AAH91163.1 361 Alpha-methylacyl-CoA racemase [Rattus norvegicus]
GI:401709963 GenBank EDL82982.1 382 alpha-methylacyl-CoA racemase [Rattus norvegicus]
GI:401709963 SwissProt P70473.3 382 RecName: Full=Alpha-methylacyl-CoA racemase; AltName: Full=2-arylpropionyl-CoA epimerase; AltName: Full=2-methylacyl-CoA racemase [Rattus norvegicus]