Gene/Proteome Database (LMPD)

LMPD ID
LMP012496
Gene ID
25291
Species
Rattus norvegicus (Rat)
Gene Name
annexin A3
Gene Symbol
Anxa3
Synonyms
LC3; Anx3; LRRGT00047;
Alternate Names
annexin A3; PAP-III; annexin-3; lipocortin III; 35-alpha calcimedin; Annexin III (Lipocortin III); placental anticoagulant protein III;
Chromosome
14
Map Location
14p22
Summary
inhibits phospholipase A2 activity [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Anxa3

Proteins

annexin A3
Refseq ID NP_036955
Protein GI 401709965
UniProt ID P14669
mRNA ID NM_012823
Length 324
MAASLWVGPRGTINNYPGFNPSVDAEAIRKAIKGIGTDEKTLINILTERSNAQRQLIVKQYQEAYEQALKADLKGDLSGHFEHVMVALITAPAVFDAKQLKKSMRGMGTDEDTLIEILTTRTSRQMKEISQAYYTAYKKNLRDDISSETSGDFRKALLTLADGGRDESLKVDEHLAKKDAQTLYDAGEKKWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAVVRCTRNTPAFLAGRLHQALKGAGTDEFTLNRIMVSRSEIDLLDIRREFKKHYGCSLYSAIQSDTSGDYRTVLLKICGGDD

Gene Information

Entrez Gene ID
25291
Gene Name
annexin A3
Gene Symbol
Anxa3
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0030424 IDA:RGD C axon
GO:0030425 IDA:RGD C dendrite
GO:0043025 IDA:RGD C neuronal cell body
GO:0005509 IEA:InterPro F calcium ion binding
GO:0005544 IDA:RGD F calcium-dependent phospholipid binding
GO:0019834 IDA:RGD F phospholipase A2 inhibitor activity
GO:0021766 IEP:RGD P hippocampus development
GO:0043086 IDA:GOC P negative regulation of catalytic activity
GO:0031100 IEP:RGD P organ regeneration
GO:0051054 IMP:RGD P positive regulation of DNA metabolic process
GO:0051384 IEP:RGD P response to glucocorticoid
GO:0070848 IEP:RGD P response to growth factor

Domain Information

InterPro Annotations

Accession Description
IPR001464 Annexin
IPR018252 Annexin repeat, conserved site
IPR002390 Annexin, type III
IPR018502 Annexin_repeat

UniProt Annotations

Entry Information

Gene Name
annexin A3
Protein Entry
ANXA3_RAT
UniProt ID
P14669
Species
Rat

Comments

Comment Type Description
Domain A pair of annexin repeats may form one binding site for calcium and phospholipid.
Function Inhibitor of phospholipase A2, also possesses anti- coagulant properties.
Similarity Belongs to the annexin family
Similarity Contains 4 annexin repeats

Identical and Related Proteins

Unique RefSeq proteins for LMP012496 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
401709965 RefSeq NP_036955 324 annexin A3

Identical Sequences to LMP012496 proteins

Reference Database Accession Length Protein Name
GI:401709965 GenBank EDL99638.1 324 annexin A3, isoform CRA_b [Rattus norvegicus]
GI:401709965 RefSeq XP_006250756.1 324 PREDICTED: annexin A3 isoform X1 [Rattus norvegicus]
GI:401709965 RefSeq XP_006250758.1 324 PREDICTED: annexin A3 isoform X1 [Rattus norvegicus]
GI:401709965 SwissProt P14669.4 324 RecName: Full=Annexin A3; AltName: Full=35-alpha calcimedin; AltName: Full=Annexin III; AltName: Full=Annexin-3; AltName: Full=Lipocortin III; AltName: Full=Placental anticoagulant protein III; Short=PAP-III [Rattus norvegicus]

Related Sequences to LMP012496 proteins

Reference Database Accession Length Protein Name
GI:401709965 GenBank EDL99638.1 324 annexin A3, isoform CRA_b [Rattus norvegicus]
GI:401709965 RefSeq XP_006250756.1 324 PREDICTED: annexin A3 isoform X1 [Rattus norvegicus]
GI:401709965 RefSeq XP_006250758.1 324 PREDICTED: annexin A3 isoform X1 [Rattus norvegicus]