Gene/Proteome Database (LMPD)

LMPD ID
LMP012552
Gene ID
25716
Species
Rattus norvegicus (Rat)
Gene Name
synaptotagmin I
Gene Symbol
Syt1
Synonyms
P65;
Alternate Names
synaptotagmin-1; sytI; synaptotagmin 1;
Chromosome
7
Map Location
7q21
Summary
integral component of synaptic vesicle membranes; important for exocytosis and vesicle trafficking to the active zone of synapses; may be the calcium sensor for calcium-dependent exocytosis [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Syt1

Proteins

synaptotagmin-1
Refseq ID NP_001028852
Protein GI 148356226
UniProt ID Q707P0
mRNA ID NM_001033680
Length 421
MVSASHPEALAAPVTTVATLVPHNATEPASPGEGKEDAFSKLKQKFMNELHKIPLPPWALIAIAIVAVLLVVTCCFCVCKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVKK

Gene Information

Entrez Gene ID
25716
Gene Name
synaptotagmin I
Gene Symbol
Syt1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0043005 IEA:Ensembl C neuron projection
GO:0042734 IEA:Ensembl C presynaptic membrane
GO:0030141 IEA:Ensembl C secretory granule
GO:0030672 IEA:Ensembl C synaptic vesicle membrane
GO:0005509 IEA:Ensembl F calcium ion binding
GO:0016079 IEA:Ensembl P synaptic vesicle exocytosis

KEGG Pathway Links

KEGG Pathway ID Description
ko04721 Synaptic vesicle cycle
rno04721 Synaptic vesicle cycle

REACTOME Pathway Links

REACTOME Pathway ID Description
5954090 Acetylcholine Neurotransmitter Release Cycle
5954111 GABA synthesis, release, reuptake and degradation
5953278 Glutamate Neurotransmitter Release Cycle
5953277 Neuronal System
5953279 Neurotransmitter Release Cycle
5954116 Norepinephrine Neurotransmitter Release Cycle
5953276 Transmission across Chemical Synapses

Domain Information

InterPro Annotations

Accession Description
IPR015428 Synaptotagmin 1

UniProt Annotations

Entry Information

Gene Name
synaptotagmin I
Protein Entry
Q707P0_RAT
UniProt ID
Q707P0
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP012552 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
148356226 RefSeq NP_001028852 421 synaptotagmin-1

Identical Sequences to LMP012552 proteins

Reference Database Accession Length Protein Name
GI:148356226 EMBL CAE85101.1 421 synaptotagmin 1 [Rattus rattus]
GI:148356226 GenBank ABA00482.1 421 synaptotagmin I [Rattus norvegicus]
GI:148356226 SwissProt P21707.3 421 RecName: Full=Synaptotagmin-1; AltName: Full=Synaptotagmin I; Short=SytI; AltName: Full=p65 [Rattus norvegicus]

Related Sequences to LMP012552 proteins

Reference Database Accession Length Protein Name
GI:148356226 EMBL CAE85101.1 421 synaptotagmin 1 [Rattus rattus]
GI:148356226 GenBank ABA00482.1 421 synaptotagmin I [Rattus norvegicus]
GI:148356226 SwissProt P21707.3 421 RecName: Full=Synaptotagmin-1; AltName: Full=Synaptotagmin I; Short=SytI; AltName: Full=p65 [Rattus norvegicus]