Gene/Proteome Database (LMPD)

LMPD ID
LMP012567
Gene ID
29204
Species
Rattus norvegicus (Rat)
Gene Name
sialidase 2
Gene Symbol
Neu2
Alternate Names
sialidase-2; neuraminidase 2; cytosolic sialidase; N-acetyl-alpha-neuraminidase 2;
Chromosome
9
Map Location
9q36
Summary
cytosolic enzyme that cleaves sialic acid; involved in the degradation of glycolipids and glycoproteins [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Neu2

Proteins

sialidase-2
Refseq ID NP_058826
Protein GI 126723022
UniProt ID Q5BK97
mRNA ID NM_017130
Length 379
METCPVLQKETLFHTEVYAYRIPALLYLKKQKTLLAFAEKRASRTDEHAELIVLRRGSYNGATNHVKWQPEEVVTQAQLEGHRSMNPCPLYDKQTKTLFLFFIAVPGRVSEQHQLQTRVNVTRLCRVTSTDYGMNWSPVQDLTETTIGSTHQDWATFAVGPGHCLQLRNRAGSLLVPAYAYQKLHPVHKPTPFAFCFISLDHGHTWELGNFVSENSLECQVAEVGTGAHRVVYLNARSFIGARVQAQSPNDGLDFQDNQVVSKLVEPPHGCHGSVVAFHSPTSKPDALDMWLLYTHPTDSRNRTNLGVYLNQTPLDPTAWSEPTLLATGTCAYSDLQNMGRGPDGSPQFGCLYESGNYDEIIFLMFTLKQAFPTVHGAQ

Gene Information

Entrez Gene ID
29204
Gene Name
sialidase 2
Gene Symbol
Neu2
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0052794 IEA:Ensembl F exo-alpha-(2->3)-sialidase activity
GO:0006689 IEA:Ensembl P ganglioside catabolic process
GO:0009313 IEA:Ensembl P oligosaccharide catabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ko00511 Other glycan degradation
rno00511 Other glycan degradation
ko00600 Sphingolipid metabolism
rno00600 Sphingolipid metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
5953739 Asparagine N-linked glycosylation
5953738 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
5954485 Glycosphingolipid metabolism
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5953345 Metabolism of proteins
5953728 Post-translational protein modification
5954270 Sialic acid metabolism
5954267 Sphingolipid metabolism
5953737 Synthesis of substrates in N-glycan biosythesis

Domain Information

InterPro Annotations

Accession Description
IPR026856 Sialidase family
IPR026945 Sialidase-2
IPR011040 Sialidases

UniProt Annotations

Entry Information

Gene Name
sialidase 2
Protein Entry
Q5BK97_RAT
UniProt ID
Q5BK97
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP012567 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
126723022 RefSeq NP_058826 379 sialidase-2

Identical Sequences to LMP012567 proteins

Reference Database Accession Length Protein Name
GI:126723022 RefSeq XP_006245427.1 379 PREDICTED: sialidase-2 isoform X1 [Rattus norvegicus]
GI:126723022 RefSeq XP_008765431.1 379 PREDICTED: sialidase-2 isoform X1 [Rattus norvegicus]
GI:126723022 RefSeq XP_008765432.1 379 PREDICTED: sialidase-2 isoform X1 [Rattus norvegicus]
GI:126723022 RefSeq XP_008765433.1 379 PREDICTED: sialidase-2 isoform X1 [Rattus norvegicus]

Related Sequences to LMP012567 proteins

Reference Database Accession Length Protein Name
GI:126723022 RefSeq XP_008765431.1 379 PREDICTED: sialidase-2 isoform X1 [Rattus norvegicus]
GI:126723022 RefSeq XP_008765432.1 379 PREDICTED: sialidase-2 isoform X1 [Rattus norvegicus]
GI:126723022 RefSeq XP_008765433.1 379 PREDICTED: sialidase-2 isoform X1 [Rattus norvegicus]