Gene/Proteome Database (LMPD)

LMPD ID
LMP012616
Gene ID
29611
Species
Rattus norvegicus (Rat)
Gene Name
dihydrolipoamide branched chain transacylase E2
Gene Symbol
Dbt
Alternate Names
lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial;
Chromosome
2
Map Location
2q41
Summary
a component of the branched-chain alpha-keto acid dehydrogenase complex; involved in the catabolism of the branched-chain amino acids, isoleucine, leucine, and valine [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Dbt

Proteins

lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
Refseq ID NP_445764
Protein GI 158749632
UniProt ID Q99PU6
mRNA ID NM_053312
Length 482
MAAARVLGTWSRNAVRLTCVRYFQTYNNVHILKPQHVCSVGYPLLKSSQPRHSLRTAAVLQGQVVQFKLSDIGEGIREVTIKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKRLYYNLDDIAYVGKPLIDIETEALKDSEEDVVETPAVAHDEHTHQEIKGQKTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNFLEKQTGAILPPSPKSEITPPPPQPRDRPFPTPVSKPPVFLGKDRTEPVTGFQKAMVKTMSAALKIPHFGYCDEVDLTELVKLREELKPVALARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQSITYKASHNIGIAMDTERGLIVPNVKNVQVRSVFEIAMELNRLQKLGSLGQLSTTDLTGGTFTLSNIGSIGGTYAKPVILPPEVAIGALGAIKALPRFDQKGDVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLDLK

Gene Information

Entrez Gene ID
29611
Gene Name
dihydrolipoamide branched chain transacylase E2
Gene Symbol
Dbt
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0042645 IEA:Ensembl C mitochondrial nucleoid
GO:0016746 IEA:UniProtKB-KW F transferase activity, transferring acyl groups

KEGG Pathway Links

KEGG Pathway ID Description
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA
rno01100 Metabolic pathways
ko00280 Valine, leucine and isoleucine degradation
rno00280 Valine, leucine and isoleucine degradation

REACTOME Pathway Links

REACTOME Pathway ID Description
5953282 Branched-chain amino acid catabolism
5953250 Metabolism
5953272 Metabolism of amino acids and derivatives

Domain Information

InterPro Annotations

Accession Description
IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site
IPR000089 Biotin/lipoyl attachment
IPR004167 E3-binding domain
IPR015761 Lipoamide Acyltransferase
IPR011053 Single hybrid motif

UniProt Annotations

Entry Information

Gene Name
dihydrolipoamide branched chain transacylase E2
Protein Entry
Q99PU6_RAT
UniProt ID
Q99PU6
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP012616 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
158749632 RefSeq NP_445764 482 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

Identical Sequences to LMP012616 proteins

Reference Database Accession Length Protein Name
GI:158749632 GenBank EDL82034.1 482 dihydrolipoamide branched chain transacylase E2, isoform CRA_b [Rattus norvegicus]
GI:158749632 GenBank AAI66487.1 482 Dihydrolipoamide branched chain transacylase E2 [Rattus norvegicus]

Related Sequences to LMP012616 proteins

Reference Database Accession Length Protein Name
GI:158749632 GenBank EDL82034.1 482 dihydrolipoamide branched chain transacylase E2, isoform CRA_b [Rattus norvegicus]
GI:158749632 GenBank AAI66487.1 482 Dihydrolipoamide branched chain transacylase E2 [Rattus norvegicus]
GI:158749632 RefSeq NP_034152.2 482 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial [Mus musculus]